Role of Tyrosine Kinases in Gastrointestinal Malignancies, Ganji Purnachandra Nagaraju
Автор: David Bentrem; Al B. Benson Название: Gastrointestinal Malignancies ISBN: 3319817124 ISBN-13(EAN): 9783319817125 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book comprehensively summarizes the current state of knowledge on malignancies of the gastrointestinal tract. Dedicated organ-based chapters evaluate current treatments and management and provide information on incidence, etiology and biological characteristics. The state of the art in the radiologic and endoscopic staging of gastrointestinal malignancies is described, and guidance is offered on the role of interventional radiology and interventional gastroenterology in the treatment of these challenging tumors. In addition, the book explores novel and evolving treatments, including personalized systemic therapy and minimally invasive surgical and radiology techniques, and addresses patient-reported outcomes and survivorship challenges. It closes by discussing animal models of gastrointestinal malignancies and examining the significance of the Ras superfamily of GTPases. It will be of benefit to all surgeons, oncologists and other specialists who treat these malignancies, as well as to trainees looking to increase their understanding of the field.
Автор: Marc Daeron; Eric Vivier Название: Immunoreceptor Tyrosine-based Inhibition Motifs ISBN: 3642636349 ISBN-13(EAN): 9783642636349 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Novel molecular motifs named Immunoreceptor Tyrosine-based Inhibition Motifs (ITIMs) have recently been recognized in the intracytoplasmic domains of a still-increasing number of receptors which control cell activation and proliferation.
Описание: Proceedings of the NATO Advanced Study Institute on Tyrosine Phosphorylation/Dephosphorylation and Downstream Signalling, held at Acquafredda di Maratea, Italy, September 1-12, 1992
Автор: Haojian Zhang; Shaoguang Li Название: Leukemia Stem Cells in Hematologic Malignancies ISBN: 9811373418 ISBN-13(EAN): 9789811373411 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book introduces readers to the biology of leukemia stem cells (LSCs) and emphasizes the necessity and importance of targeting LSCs in the treatment of hematopoietic malignancies. It addresses the role of leukemia stem cells in different leukemia diseases and molecular signatures, as well as the metabolic and epigenetic regulation of leukemia stem cell function. With regard to solid tumors, a significant number of blood cancers are believed to be derived from leukemia stem cells (LSCs), which are responsible for disease progression, relapse and drug resistance. Consequently, new therapeutic strategies need to be developed by focusing on the complete eradication of LSCs. Given its scope, the book offers a valuable asset for graduate students and scientists in the fields of cell biology and cancer research etc.
Описание: Receptor Tyrosine Kinase: Structure, Functions and Role in Human Disease, for the first time, systematically covers the shared structural and functional features of the RTK family.
Описание: This volume comprehensively covers the multiplicity and diversity of mechanisms underlying patient resistance to currently approved anti-cancer drugs, including tyrosine kinase inhibitors and monoclonal antibodies, blockers of growth factor receptors and their downstream pathways, which play essential functions in cancer progression.
Описание: This volume comprehensively covers the multiplicity and diversity of mechanisms underlying patient resistance to currently approved anti-cancer drugs, including tyrosine kinase inhibitors and monoclonal antibodies, blockers of growth factor receptors and their downstream pathways, which play essential functions in cancer progression. Each chapter will cover a specific group of targets and the cognate drugs, along with molecular modes of innate and evolving resistance.
Автор: Cai Qiang, Xu Hong, El-Rayes Bassel F. Название: Gastrointestinal Malignancies: New Innovative Diagnostics and Treatment ISBN: 9814618985 ISBN-13(EAN): 9789814618984 Издательство: World Scientific Publishing Рейтинг: Цена: 24869.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Gastrointestinal Malignancies: New Innovative Diagnostics and Treatment summarizes new advantages in the diagnosis and treatment of gastrointestinal malignancies
Описание: This volume will describe both growth-inhibitory and mucin-depleting effects of bromelain and N-acetylcysteine, on their own or in combination, in cancer.
Автор: N.J. Vianna Название: Lymphoreticular Malignancies ISBN: 9401180555 ISBN-13(EAN): 9789401180559 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Frequently a singular observation resulting from this type of inquiry provides the working hypothesis for the epidemiologist who again asks the same question, not of the individual but of a definable population at risk.
Автор: Joseph A. Sparano Название: HIV & HTLV-I Associated Malignancies ISBN: 1461356350 ISBN-13(EAN): 9781461356356 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Infection with the human immunodeficiency virus (HIV) and human T-cell lymphotropic virus type I (HTLV-I) is known to be associated with an increased risk of neoplastic disorders, especially Kaposi`s sarcoma and aggressive B-cell lymphoma for the former, and T-cell lymphoma for the latter.
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