Molecular Mechanisms of Notch Signaling, Tilman Borggrefe; Benedetto Daniele Giaimo
Автор: Maulik Название: Molecular mechanisms and physiology of disease ISBN: 1493907050 ISBN-13(EAN): 9781493907052 Издательство: Springer Рейтинг: Цена: 32142.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In a simplified form, epigenetics refers to heritable changes in phenotype that are not due to changes in the underlying DNA sequence. In this book, epigenetic mechanisms of regulation and dysregulation in health and disease are explored in great depth. Detailed chapters on epigenetic processes including DNA methylation and chromatin post-translational modifications including potential interventions with DNA methyltransferase inhibitors and histone deacetylase inhibitors are explored in initial chapters. These provide a detailed overview and important background to the entire field. The book is then focussed on epigenetic mechanisms involved in various diseases including anti-inflammatory and autoimmune conditions. Important accounts relating to the effects of epigenetics in metabolic syndrome, cardiovascular disease and asthma are the focus of subsequent chapters. The role of epigenetic dysregulation in malignancy is a current topic of interest and represents an intense field of research. A large component of this book is dedicated to the analysis of aberrant epigenetic processes in carcinogenesis and cancer progression. Further, chapters are focused on emerging cancer prevention using nutritional components and anti-cancer therapies particularly with histone deacetylase inhibitors, which have already been approved for the treatment of cutaneous T-cell lymphoma. The emerging role of nanoparticle preparations, especially in the context of delivering potential epigenetic therapies to target cells in various diseases, is also explored in this book. Overall, this book encompasses a wide range of topics related to epigenetic mechanisms in health and disease and would appeal to anyone with an interest in epigenetics, chromatin biology and emerging epigenetic interventions and therapies.
Cellular Signal Processing offers a unifying view of cell signaling based on the concept that protein interactions act as sophisticated data processing networks that govern intracellular and extracellular communication. It is intended for use in signal transduction courses for undergraduate and graduate students working in biology, biochemistry, bioinformatics, and pharmacology, as well as medical students. The text is organized by three key topics central to signal transduction: the protein network, its energy supply, and its evolution. It covers all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal signaling, and also highlights the clinical aspects of cell signaling in health and disease. This new edition includes expanded coverage of prokaryotes, as well as content on new developments in systems biology, epigenetics, redox signaling, and small, non-coding RNA signaling.
Автор: G. Csaba; W.E.G. M?ller Название: Signaling Mechanisms in Protozoa and Invertebrates ISBN: 3642801080 ISBN-13(EAN): 9783642801082 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The new receptor era of mammalian endocrinology stimulated research on invertebrate hormone receptors, and sophisticated methods are applied also to determine hormones. About two decades ago, first observations on the presence of hormone receptors reacting to vertebrate hormones in protozoa were made.
Автор: Carlos Rosales Название: Molecular Mechanisms of Phagocytosis ISBN: 1489997636 ISBN-13(EAN): 9781489997630 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Although, Phagocytosis was first described nearly 120 year ago, we are just recently beginning to understand the molecules that phagocytic cells use to bring about this complex cell function.
Автор: Eckhard Boles; Reinhard Kr?mer Название: Molecular Mechanisms Controlling Transmembrane Transport ISBN: 3662308207 ISBN-13(EAN): 9783662308202 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: All living cells are strictly separated from their surroundings by a membranous lipid bilayer. In order to respond properly to a changing nutrient supply or demand, as well as to external stress factors, cells must be able to adapt both amount and activity of the corresponding transporters.
Автор: Karel W.A. Wirtz Название: Molecular Mechanisms of Signalling and Membrane Transport ISBN: 3642645593 ISBN-13(EAN): 9783642645594 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the NATO Study Institute on Molecular Mechanisms of Signalling and Targeting, held on the Island of Spetsai, Greece, August 18-30, 1996
Автор: T.M. Konijn; P.J.M. Van Haastert; H. Van der Starr Название: Molecular Mechanisms of Desensitization to Signal Molecules ISBN: 3642717845 ISBN-13(EAN): 9783642717840 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the NATO Advanced Research Workshop on Molecular and Cellular Processes Underlying Desensitization and Adaptation to Signal Molecules held at Noordwijkerhout, The Netherlands, 29-31 May, 1986
Автор: Green Название: Mechanisms of Biological Oxidations ISBN: 1107560101 ISBN-13(EAN): 9781107560109 Издательство: Cambridge Academ Рейтинг: Цена: 5859.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: David Ezra Green (1910-83) was an American biochemist who made important contributions to the field of enzymology. In this book, which was originally published in 1940, Green provides a detailed account of the `mechanisms of cellular oxidation`. Notes and illustrative figures are incorporated throughout.
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