Автор: Damien Lacroix; Marzia Brunelli; C?cile Perrault; Название: Multiscale Mechanobiology in Tissue Engineering ISBN: 9811340560 ISBN-13(EAN): 9789811340567 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book focuses on the mechanobiological principles in tissue engineering with a particular emphasis on the multiscale aspects of the translation of mechanical forces from bioreactors down to the cellular level. The book contributes to a better understanding of the design and use of bioreactors for tissue engineering and the use of mechanical loading to optimize in vitro cell culture conditions. It covers experimental and computational approaches and the combination of both to show the benefits that computational modelling can bring to experimentalists when studying in vitro cell culture within a scaffold. With topics from multidisciplinary fields of the life sciences, medicine, and engineering, this work provides a novel approach to the use of engineering tools for the optimization of biological processes and its application to regenerative medicine. The volume is a valuable resource for researchers and graduate students studying mechanobiology and tissue engineering. For undergraduate students it also provides deep insight into tissue engineering and its use in the design of bioreactors. The book is supplemented with extensive references for all chapters to help the reader to progress through the study of each topic.
Автор: Tim McGloughlin Название: Biomechanics and Mechanobiology of Aneurysms ISBN: 3642270751 ISBN-13(EAN): 9783642270758 Издательство: Springer Рейтинг: Цена: 19589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book offers new insights into aneurysm aetiology and behavior based on the most recent biomechanics research related to this important topic. It details key factors influencing aneurysm behavior and treatment.
Автор: Amit Gefen; Dafna Benayahu Название: The Mechanobiology of Obesity and Related Diseases ISBN: 3319093355 ISBN-13(EAN): 9783319093352 Издательство: Springer Рейтинг: Цена: 19591.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Mechanical behavior and properties of adipose tissue.- Mathematical models of adipose tissue dynamics.- Mechanical stretching and signaling pathways in adipogenesis- Role of mechanical stimulations in directing mesenchymal stem cell adipogenesis.- The vicious cycle of estrogen consumption and obesity: The role of mechanotransduction.- Extracellular matrix remodeling and mechanical stresses as modulators of adipose tissue metabolism and inflammation.- The Impact of Obesity and Weight Loss on Gait in Adults.- Excessive Weight Bearing Compromises Foot Structure and Function across the Lifespan.- Obesity, Osteoarthritis and Aging: The Biomechanical Links.- Impaired neutrophil mechanoregulation by fluid flow: A potential contributing factor for microvascular dysfunction in obesity.- Mechanotransduction and the myogenic response in diabetes.- Role of adipose cells in tumor microenvironment.
Автор: Suvranu De; Wonmuk Hwang; Ellen Kuhl Название: Multiscale Modeling in Biomechanics and Mechanobiology ISBN: 1447172299 ISBN-13(EAN): 9781447172291 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Presenting a state-of-the-art overview of theoretical and computational models that link characteristic biomechanical phenomena, this book provides guidelines and examples for creating multiscale models in representative systems and organisms.
Автор: Verbruggen, Stefaan Название: Mechanobiology in Health and Disease ISBN: 0128129522 ISBN-13(EAN): 9780128129524 Издательство: Elsevier Science Рейтинг: Цена: 22065.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Mechanobiology in Health and Disease brings together contributions from leading biologists, clinicians, physicists and engineers in one convenient volume, providing a unified source of information for researchers in this highly multidisciplinary area. Opening chapters provide essential background information on cell mechanotransduction and essential mechanobiology methods and techniques. Other sections focus on the study of mechanobiology in healthy systems, including bone, tendons, muscles, blood vessels, the heart and the skin, as well as mechanobiology studies of pregnancy. Final chapters address the nascent area of mechanobiology in disease, from the study of bone conditions, skin diseases and heart diseases to cancer. A discussion of future perspectives for research completes each chapter in the volume.. This is a timely resource for both early-career and established researchers working on mechanobiology.
Название: Mechanobiology Handbook ISBN: 1138072265 ISBN-13(EAN): 9781138072268 Издательство: Taylor&Francis Рейтинг: Цена: 16078.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Mechanobiology--the study of the effects of mechanical environments on the biological processes of cells--has evolved from traditional biomechanics via the incorporation of strong elements of molecular and cell biology. Currently, a broad range of organ systems are being studied by surgeons, physicians, basic scientists, and engineers. These mechanobiologists aim to create new therapies and further biological understanding by quantifying the mechanical environment of cells and the molecular mechanisms of mechanically induced pathological conditions.
To achieve these goals, investigators must be familiar with both the basic concepts of mechanics and the modern tools of cellular/molecular biology. Unfortunately, current literature contains numerous studies that misuse standard mechanical estimations and terminology, or fail to implement appropriate molecular analyses. Therefore, the Mechanobiology Handbook not only presents cutting-edge research findings across various fields and organ systems, but also provides the elementary chapters on mechanics and molecular analysis techniques to encourage cross-field understanding and appropriate planning.
Aided by the continuous advancement of research tools in both mechanics and biology, more sophisticated experiments and analyses are possible--thus fueling the growth of the field of mechanobiology. Considering the complexity of the mechanics and the biology of the human body, most of the world of biomechanics remains to be studied. Since the field is still developing, the Mechanobiology Handbook does not force one unified theory, but brings out many different viewpoints and approaches to stimulate further research questions.
Автор: El-hashash, Ahmed (the Zhejiang Univ - Univ Of Edinburgh Institute, China) Meguid, Eiman Abdel (queen`s Univ Belfast, Uk) Название: Lung, the: developmental morphogenesis, mechanobiology, and stem cells ISBN: 9813277068 ISBN-13(EAN): 9789813277069 Издательство: World Scientific Publishing Рейтинг: Цена: 12672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With detailed scientific background and up-to-date research, this book examines recent developmental and cell biology, mechanobiology and stem cell biology discoveries to help provide a better understanding of lung development, repair and regeneration.Lung regeneration is an urgent therapeutic priority. The current major challenge is the generation of complex vascularized structures that can ultimately support or replace impaired lung function. Recent discoveries in biomedical engineering are analysed within the structural context of the lung to help provide a better understanding of the innovative solutions that could be used for restoring normal morphogenesis and regeneration of the lung. This also includes insights from basic developmental mechanisms of human lung development through the derivation and identification of stem cells, both from the early embryo as well as from differentiated organs and tissues.Suitable for a wide range of readers, including physicians and surgeons, scientists and researchers, and undergraduate and postgraduate students, this guide is an essential read for those working in the field of lung disease and development.
Название: Modern Mechanobiology ISBN: 9814800589 ISBN-13(EAN): 9789814800587 Издательство: Taylor&Francis Рейтинг: Цена: 17762.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Modern mechanobiology converges both engineering and medicine to address personalized medicine. This book is built on the previously well-received edition, Hemodynamics and Mechanobiology of Endothelium. The central theme focuses on "omic" approaches to mechanosignal transduction underlying tissue development, injury, and repair.
Автор: Suvranu De; Wonmuk Hwang; Ellen Kuhl Название: Multiscale Modeling in Biomechanics and Mechanobiology ISBN: 1447165985 ISBN-13(EAN): 9781447165989 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Presenting a state-of-the-art overview of theoretical and computational models that link characteristic biomechanical phenomena, this book provides guidelines and examples for creating multiscale models in representative systems and organisms. It develops the reader's understanding of and intuition for multiscale phenomena in biomechanics and mechanobiology, and introduces a mathematical framework and computational techniques paramount to creating predictive multiscale models. Biomechanics involves the study of the interactions of physical forces with biological systems at all scales – including molecular, cellular, tissue and organ scales. The emerging field of mechanobiology focuses on the way that cells produce and respond to mechanical forces – bridging the science of mechanics with the disciplines of genetics and molecular biology. Linking disparate spatial and temporal scales using computational techniques is emerging as a key concept in investigating some of the complex problems underlying these disciplines. Providing an invaluable field manual for graduate students and researchers of theoretical and computational modelling in biology, this book is also intended for readers interested in biomedical engineering, applied mechanics and mathematical biology.
Автор: Damien Lacroix et al Название: Multiscale Mechanobiology in Tissue Engineering ISBN: 9811080747 ISBN-13(EAN): 9789811080746 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book focuses on the mechanobiological principles in tissue engineering with a particular emphasis on the multiscale aspects of the translation of mechanical forces from bioreactors down to the cellular level.
Автор: Gerhard A. Holzapfel; Raymond W. Ogden Название: Multiscale Soft Tissue Mechanics and Mechanobiology ISBN: 9402415122 ISBN-13(EAN): 9789402415124 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Поставка под заказ.
Описание: This volume covers aspects of multiscale modeling of the mechanics and mechanobiology of soft biological tissues. The individual contributions focus on the constitutive modeling from the micro to the macro level in addition to computational modeling and simulation. It consists of peer-reviewed papers written by leading international authorities and will serve as a major state-of-the-art source of reference for the next few years. It includes both review articles and original articles. Previously published in the Journal of Elasticity, Volume 129, Issue 1-2, December 2017.
Автор: A. Wagoner Johnson; Brendan Harley Название: Mechanobiology of Cell-Cell and Cell-Matrix Interactions ISBN: 1489973796 ISBN-13(EAN): 9781489973795 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume examines interactions between cells and their local extracellular environment, exploring how these may mediate cell behavior. Topics include integrin-ligand interactions; cooperative mechanisms of cell-matrix interactions and quantitative methods.
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