Mitogen-Activated Protein Kinases (MAPKs): Activation, Functions and Regulation, Charles K Hester
Автор: Francesc Posas; Angel R. Nebreda Название: Stress-Activated Protein Kinases ISBN: 3642094805 ISBN-13(EAN): 9783642094804 Издательство: Springer Рейтинг: Цена: 40389.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this book leading researchers in the field discuss the state-of-the-art of many aspects of SAPK signaling in various systems from yeast to mammals.
Описание: Describing the use of biophysical and biochemical methods to prove that calcium has a positive feedback effect on amplifying and sustaining CD3 phosphorylation and should enhance T-cell sensitivity to foreign antigens, this thesis couples the use of nuclear magnetic resonance (NMR) to the analysis of signaling phenomena in living cells.
Описание: This thesis describes the use of biophysical and biochemical methods to prove that calcium has a positive feedback effect on amplifying and sustaining CD3 phosphorylation and should enhance T-cell sensitivity to foreign antigens. The study presented shows that calcium can regulate the signal pathway in cells not only as a secondary messenger but also through direct interactions with the phospholipid bilayer. The approach used in the thesis also represents an important advance, as it couples the use of nuclear magnetic resonance (NMR) to the analysis of signaling phenomena in living cells. Moreover, the thesis optimizes the Nanodisc assembly protocol, which can broaden its range of applications in membrane protein studies. A preliminary study on the structure of dengue virus NS2B-NS3p in complex with aprotinin, which may help to develop new drugs against the dengue virus, is also included.
Автор: Sudhir Gupta; William E. Paul; Ralph Steinman Название: Mechanisms of Lymphocyte Activation and Immune Regulation X ISBN: 1441937005 ISBN-13(EAN): 9781441937001 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume is edited by Dr. Sudhir Gupta, internationally recognized expert in Immunology, Professor of Medicine, Pathology, Microbiology and Molecular Genetics. Topics include toll receptors, dendritic cells, NK cells, and complement receptors.
Автор: Hsing-Jien Kung; Peter K. Vogt Название: Retroviral Insertion and Oncogene Activation ISBN: 3642765262 ISBN-13(EAN): 9783642765261 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: An integrated retrovirus effectively becomes part of the cellular genome, but with the difference that the virus to a large extent retains control over its own expression through nontranslated sequences in the long terminal repeat (L TR).
Автор: Stephen W. Russell; Siamon Gordon Название: Macrophage Biology and Activation ISBN: 3642773796 ISBN-13(EAN): 9783642773792 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The aspects covered in this volume have been selected to provide an overview of subject areas that either have recently become much better understood or hold the promise of new levels of understanding as they are developed in the future.
Автор: T.M. Konijn; M.D. Houslay; P.J.M. van Haastert Название: Activation and Desensitization of Transducing Pathways ISBN: 3642836208 ISBN-13(EAN): 9783642836206 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the NATO Advanced Research Workshop on Activation and Desensitization of Transducing Pathways held at Noordwijkerhout, The Netherlands, May 25-27, 1989
Описание: Peroxisome Proliferator Activated Receptors (PPARs) attract great attention in light of the wide spectrum of genes of biological and medical relevance identified as under their control. This volume provides a view of the clinical and scientific developments within this area of study.
Автор: Jihan A. Youssef; Mostafa Z. Badr Название: Peroxisome Proliferator-Activated Receptors ISBN: 1627034196 ISBN-13(EAN): 9781627034197 Издательство: Springer Рейтинг: Цена: 22203.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book reviews the history of PPAR discovery and details receptor structure and its posttranslational modifications, discusses endogenous and exogenous ligands, the tissue distribution and versatile functions of PPAR subtypes in major organs and much more.
Описание: Peroxisome Proliferator Activated Receptors (PPARs) attract great attention in light of the wide spectrum of genes of biological and medical relevance identified as under their control.
Описание: Receptor Tyrosine Kinase: Structure, Functions and Role in Human Disease, for the first time, systematically covers the shared structural and functional features of the RTK family.
Автор: Jenny, Andreas Название: Protein Kinases in Development and Disease,123 ISBN: 0128015136 ISBN-13(EAN): 9780128015131 Издательство: Elsevier Science Рейтинг: Цена: 26107.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Protein Kinases in Development and Disease discusses and reviews important, but often neglected, kinases. A good representation of current model organisms from plants and C. elegans to mice are used as the basis to illustrate how we can use our understanding of normal development to learn about disease.
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