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Proteases: Functions, Mechanisms and Uses, Nelson PA©rez Guerra


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Автор: Nelson PA©rez Guerra
Название:  Proteases: Functions, Mechanisms and Uses
ISBN: 9781536158540
Издательство: Nova Science
Классификация:
ISBN-10: 1536158542
Обложка/Формат: Hardback
Страницы: 322
Вес: 0.56 кг.
Дата издания: 01.10.2019
Серия: Biology
Язык: English
Размер: H 229 X W 152
Ключевые слова: Biochemistry
Подзаголовок: Functions, mechanisms and uses
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Поставляется из: Англии
Описание: Proteases or proteinases have a wide application in different industrial processes including cheese production, meat tenderization, production of protein hydrolysates, silver recovery and silk; in many other fields including biotechnological, baking, textiles, pharmaceutical and leather industries and also, as an additive to detergents and in bioremediation procedures. These enzymes are present in plants, animals and microorganisms (protozoa, bacteria, fungus and some types of algae and viruses). Considering the wide applications of these enzymes, it is necessary to know their functions, origin (plants, animals, bacteria and fungus), classification and characteristics, action mechanisms, their specific target substrates and products obtained in the reactions that these enzymes catalyze, as well as their optimal temperature and pH of activity and stability. The book provides an overview of the latest knowledge about the functions and action mechanisms of protease enzymes and their applications in different industrial fields. It addresses four important aspects: the main characteristics of proteases of different origins, the design of emerging technologies for production of novel proteases with enhanced specificity, stability and catalytic activity for a wide industrial application, utilization of proteases to produce functional foods and the use of protease inhibitors to control or block the activity of these enzymes for preventing diseases in humans and animals. It was felt necessary to include a chapter based on the use of bioinformatics resources (databases, tools, visualization and data analysis) to provide a better understanding of proteases and their functions at the molecular level. Although production and application of bacterial and fungal proteases have long been reported, little is known about the proteases produced by insects (mainly those economic and medically important species), organisms inhabiting marine environments and protozoa, their action mechanisms, properties and physiology. This knowledge is important for designing new strategies for herbivory insect control to avoid the transmission or development of pathogens in their corresponding entity hosts (in case of insect digestive proteases), or designing specific antiparasitic drugs to block the action of proteases and avoid colonization and imminent parasitism (in case of protozoa proteases). In addition, the knowledge about the integrity and function of marine proteases under extreme reaction conditions could facilitate their application in a wider processing conditions than the terrestrial proteases.


PROTEASES: Potential Role in Health and Disease

Автор: Walter H. Horl
Название: PROTEASES: Potential Role in Health and Disease
ISBN: 1461593573 ISBN-13(EAN): 9781461593577
Издательство: Springer
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Цена: 6986.00 р.
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Proteases in Health and Disease

Название: Proteases in Health and Disease
ISBN: 1461492327 ISBN-13(EAN): 9781461492320
Издательство: Springer
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Цена: 23508.00 р.
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Описание: In view of rapidly growing research in the deregulation of proteases and their impact in human health and diseases, this book will highlight existing and emerging research in this exciting area.

The ADAM Family of Proteases

Автор: Nigel M Hooper; Uwe Lendeckel
Название: The ADAM Family of Proteases
ISBN: 1441937757 ISBN-13(EAN): 9781441937759
Издательство: Springer
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Цена: 26120.00 р.
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Описание: The ADAM Family of Proteases provides the first comprehensive review of the roles of ADAMs and the related ADAMTS proteases in biology and disease.

Proteases and Their Receptors in Inflammation

Автор: Nathalie Vergnolle; Michel Chignard
Название: Proteases and Their Receptors in Inflammation
ISBN: 3034803427 ISBN-13(EAN): 9783034803427
Издательство: Springer
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Цена: 26120.00 р.
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Описание:

Proteases are everywhere from prokaryotes to eukaryotes, from virus to bacteria and in all human tissues, playing a role in many biological functions. Among these functions, the inflammatory reaction is of particular interest. In inflamed tissues, proteases can have a microbial and/or host origin and are involved not only in tissue remodeling, but also in specific signaling to resident or inflammatory cells, thereby contributing to the innate immune response.

This volume presents all advances in our knowledge of the role proteases and their inhibitors play in various diseases associated with inflammatory response. Mechanisms involved in protease signaling to cells are presented, and the different types of proteases that are present at inflammatory sites and their effects on the course of inflammation are discussed. Finally, the evidence for considering proteases and their receptors as potential molecular targets for therapeutic interventions in the treatment of inflammatory diseases is discussed in the context of specific organ inflammatory pathologies (the lung, gastrointestinal tract, skin, joints, etc.).

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Proteases in Health and Disease

Автор: Sajal Chakraborti; Naranjan S. Dhalla
Название: Proteases in Health and Disease
ISBN: 1493948539 ISBN-13(EAN): 9781493948536
Издательство: Springer
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Цена: 20896.00 р.
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Описание: In view of rapidly growing research in the deregulation of proteases and their impact in human health and diseases, this book will highlight existing and emerging research in this exciting area.

Enzymology at the Membrane Interface: Intramembrane Proteases,584

Автор: Gelb, Michael H
Название: Enzymology at the Membrane Interface: Intramembrane Proteases,584
ISBN: 0128122137 ISBN-13(EAN): 9780128122136
Издательство: Elsevier Science
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Цена: 24423.00 р.
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Описание:

Enzymology at the Membrane Interface: Intramembrane Proteases, Volume 584, the latest release in the Methods in Enzymology series, covers a subset of enzymes that work in the environment of the biological cell membrane. This field, called interfacial enzymology, involves a special series of experimental approaches for the isolation and study of these enzymes.

Activation of Viruses by Host Proteases

Автор: B?ttcher-Friebertsh?user
Название: Activation of Viruses by Host Proteases
ISBN: 3319754734 ISBN-13(EAN): 9783319754734
Издательство: Springer
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Цена: 25155.00 р.
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Описание: The third part will contain a chapter on protease inhibitors that are promising tools for antiviral therapy. This book will engage scholars in virology and medical microbiology as well as researchers with an interest in enzymology and protein structure and function relationship.

Serine Proteases and Their Serpin Inhibitors in the Nervous System

Автор: Barry W. Festoff
Название: Serine Proteases and Their Serpin Inhibitors in the Nervous System
ISBN: 1468483595 ISBN-13(EAN): 9781468483598
Издательство: Springer
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Цена: 6986.00 р.
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Описание: Proceedings of a NATO ARW held in Maratea, Italy, July 2-8, 1989

Role of Proteases in Cellular Dysfunction

Автор: Naranjan S. Dhalla; Sajal Chakraborti
Название: Role of Proteases in Cellular Dysfunction
ISBN: 149394634X ISBN-13(EAN): 9781493946341
Издательство: Springer
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Цена: 23508.00 р.
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Описание: This volume explores the role of proteases in various diseases. It provides information on the pathogenesis of cellular dysfunction, with strong emphasis on identifying proteases and their endogenous inhibitors as targets for drug development.

Role of Proteases in Cellular Dysfunction

Автор: Chakraborti Sajal
Название: Role of Proteases in Cellular Dysfunction
ISBN: 1461490987 ISBN-13(EAN): 9781461490982
Издательство: Springer
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Цена: 28734.00 р.
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Описание: This volume explores the role of proteases in various diseases. It provides information on the pathogenesis of cellular dysfunction, with strong emphasis on identifying proteases and their endogenous inhibitors as targets for drug development.

Proteases New Perspectives

Автор: Vito Turk
Название: Proteases New Perspectives
ISBN: 3034897502 ISBN-13(EAN): 9783034897501
Издательство: Springer
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Цена: 13974.00 р.
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Описание: This book provides an account of the recent advances in our understanding of the role of proteases under physiological and pathological conditions.

Proteases as Targets for Therapy

Автор: Klaus, von der Helm; Bruce D. Korant; John C. Cher
Название: Proteases as Targets for Therapy
ISBN: 3642630235 ISBN-13(EAN): 9783642630231
Издательство: Springer
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Цена: 18284.00 р.
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Описание: With contributions by numerous experts


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