Описание: We are pleased to announce that A Critical History of Financial Crises has been included in CHOICE Magazine's Outstanding Academic Title list. Only the most outstanding works have been selected for their excellence in scholarship and presentation, the significance of their contribution to the field, and their value as important — often the first — treatment of their subject.For more information on CHOICE Magazine's Outstanding Academic Title list, please visit the following link: www.choice360.org/products/magazine /remove 'While each financial crisis is unique and has its own special features, there are a lot of similarities in the dynamics leading to a crisis and also in their resolutions. Some of the financial crises are caused by the lack of appropriate regulation, but often the regulators were ignoring the signals of imminent crises, while serving implicitly or explicitly, the financial industry.In his book, Prof. Kedar-Levy is providing a fresh look at many famous financial crises around the globe, analysing their causes and effects. The special role of regulators is highlighted, including the 'Capture Theory' in practice. This book is suitable for economist as well as for those interested in economic history, and for all those concerned with the stability of current international financial markets.'Professor Dan GalaiThe Hebrew University, Jerusalem
Автор: Lorin W. Roberts; R.D. Preston; Peter B. Gahan; Ro Название: Vascular Differentiation and Plant Growth Regulators ISBN: 3642734480 ISBN-13(EAN): 9783642734489 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The vascular tissue of higher plants has been an object of continuous detailed study since the invention of the light microscope. As relevant new physical, chemical and biochemical techniques and concepts have appeared over the years, they have regularly and immediately been applied to this field of enquiry. The reasons are not far to seek. Vascular tissue provides the long-distance transport system for water and nutrients within the plant, and an understanding of the structure and development of the pathways within it is essential for an under- standing of growth in all higher plants, including crop plants. Moreover, parts of the vascular tissue - the whole of the xylem and the fibers of the proble- have been, and still are, in high demand commercially for their unique properties and as the only renewable structural material on earth. There are, in addition, more subtle ways in which xylogenesis, particularly as it allows the development of tree species, contributes to the environment. A few years ago, while walking in the foothills of the Pyrenees, I found all this expressed more elegantly than I can express it, in a plea carved in wood at the entrance to a forest: Homme Je suis la chaleur de ton foyer par les froids nuits d'hiver, l'ombrage ami lorsque brule Ie soleil d'ete, l'eau des rivieres et des sources. Je suis la charpente de ta maison, la planche de ta table.
Описание: Argues that the root cause of the financial crisis is the ambition to handle risk as a well-defined commodity that can be traded in the market. The book provides an interpretation of the crisis going beyond simple reconstructions. Finance cannot be rescued by simply referring to ethics or limiting the remuneration of managers.
Автор: Anandhakumar Chandran Название: Advancing Development of Synthetic Gene Regulators ISBN: 9811065462 ISBN-13(EAN): 9789811065460 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Herein is described a method that was developed using high-throughput sequencing to map the differential binding sites and relative enriched regions of non-cross-linked SAHA-PIPs throughout the complex human genome.
Описание: Chemistry of Plant Protection, Volume 7, provides critical review articles on new aspects of herbicide resis- tance, serving the needs of research scientists, pesticide manufacturers, government regulators, agricultural practitioners.
Автор: George G. Chen; Paul B.S. Lai Название: Novel Apoptotic Regulators in Carcinogenesis ISBN: 9400794932 ISBN-13(EAN): 9789400794931 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Our recent understanding of the cellular and molecular defects and the regulation of the apoptotic signalling pathways has resulted in rationally designed anticancer strategies and the development of novel agents that regulates apoptosis. A comprehensive review of all apoptotic-related anticancer therapies is not the purpose of this book. However, in the volume of this book with 11 chapters, we have described a number of novel apoptotic regulators that have shown promising value and also great feasibility for cancer treatment. These novel agents either occur naturally or are chemically synthesized. While we are excited about the discovery and development of these novel apoptotic regulators as potential anticancer agents, a degree of caution should be always borne in mind when interpreting the success of preclinical pro-apoptotic candidates since potential problems inevitably lie ahead. These problems usually include target specificity, unanticipated toxicity, compound stability, formulation issues, pharmacokinetic and pharmacodynamic profiles. Nevertheless, we believe that this collection of 11 chapters by established leaders in the area of apoptosis will be of great interest to not only academics working in the field of cancer research and apoptosis but also pharmaceutical and pharmacological industries that . We are looking forward to the further development to push these potential agents toward clinical stage.
Описание: The book brings together Inspection skills for frontline staff. It is a coherent framework of practice, theory, ethics and competency drawing on academic and professional sources. It contains comprehensive sections on Risk, Standards, Planning, Inspection and Improvement. The book provides a step-by-step guide through an inspection or audit using the model 'Plan, Inspect and Improve', stages designed to identify problems and to promote improvement. Authoritative and fully referenced, it is approximately 42000 words and available in paperback and e-book.'A splendid contribution', John Braithwaite, Australian National University. 'It is a very useful and distinctive contribution to the literature on regulation, a hands-on approach that will be of considerable value to front-line regulators' Neil Gunningham, Australian National University
Автор: Healy Judith Название: Improving Health Care Safety and Quality: Reluctant Regulators ISBN: 0754676447 ISBN-13(EAN): 9780754676447 Издательство: Taylor&Francis Рейтинг: Цена: 22968.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Responding to the alarm caused by recent hospital scandals and accounts of unintended harm to patients, this author draws on her experience of analyzing the health care systems of over a dozen countries and examines whether greater regulation has increased patient safety and health care quality. It will be of key interest to government actors, health care professionals and medico-legal scholars.
Автор: Anandhakumar Chandran Название: Advancing Development of Synthetic Gene Regulators ISBN: 9811348995 ISBN-13(EAN): 9789811348990 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This book focuses on an “outside the box” notion by utilizing the powerful applications of next-generation sequencing (NGS) technologies in the interface of chemistry and biology. In personalized medicine, developing small molecules targeting a specific genomic sequence is an attractive goal. N-methylpyrrole (P)–N-methylimidazole (I) polyamides (PIPs) are a class of small molecule that can bind to the DNA minor groove. First, a cost-effective NGS (ion torrent platform)-based Bind-n-Seq was developed to identify the binding specificity of PIP conjugates in a randomized DNA library. Their biological influences rely primarily on selective DNA binding affinity, so it is important to analyze their genome-wide binding preferences. However, it is demanding to enrich specifically the small-molecule-bound DNA without chemical cross-linking or covalent binding in chromatinized genomes. Herein is described a method that was developed using high-throughput sequencing to map the differential binding sites and relative enriched regions of non-cross-linked SAHA-PIPs throughout the complex human genome. SAHA-PIPs binding motifs were identified and the genome-level mapping of SAHA-PIPs-enriched regions provided evidence for the differential activation of the gene network. A method using high-throughput sequencing to map the binding sites and relative enriched regions of alkylating PIP throughout the human genome was also developed. The genome-level mapping of alkylating the PIP-enriched region and the binding sites on the human genome identifies significant genomic targets of breast cancer. It is anticipated that this pioneering low-cost, high through-put investigation at the sequence-specific level will be helpful in understanding the binding specificity of various DNA-binding small molecules, which in turn will be beneficial for the development of small-molecule-based drugs targeting a genome-level sequence.
Автор: Alexander Reznikov; Norbert Schappacher Название: Regulators in Analysis, Geometry and Number Theory ISBN: 1461270898 ISBN-13(EAN): 9781461270898 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is an outgrowth of the Workshop on "Regulators in Analysis, Geom- etry and Number Theory" held at the Edmund Landau Center for Research in Mathematical Analysis of The Hebrew University of Jerusalem in 1996. During the preparation and the holding of the workshop we were greatly helped by the director of the Landau Center: Lior Tsafriri during the time of the planning of the conference, and Hershel Farkas during the meeting itself. Organizing and running this workshop was a true pleasure, thanks to the expert technical help provided by the Landau Center in general, and by its secretary Simcha Kojman in particular. We would like to express our hearty thanks to all of them. However, the articles assembled in the present volume do not represent the proceedings of this workshop; neither could all contributors to the book make it to the meeting, nor do the contributions herein necessarily reflect talks given in Jerusalem. In the introduction, we outline our view of the theory to which this volume intends to contribute. The crucial objective of the present volume is to bring together concepts, methods, and results from analysis, differential as well as algebraic geometry, and number theory in order to work towards a deeper and more comprehensive understanding of regulators and secondary invariants. Our thanks go to all the participants of the workshop and authors of this volume. May the readers of this book enjoy and profit from the combination of mathematical ideas here documented.
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