Автор: Frank-Michael Matysik Название: Advances in Chemical Bioanalysis ISBN: 3319343130 ISBN-13(EAN): 9783319343136 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Expert authors provide critical, in-depth reviews of available methods for retrieving selective information out of complex biological systems. Coverage of this volume includes sensor development for the detection of small analytes, monitoring of biomolecular interactions, analysis of cellular function, development of diagnostic tools.
Автор: Bernhard Sonnleitner Название: Bioanalysis and Biosensors for Bioprocess Monitoring ISBN: 3662156385 ISBN-13(EAN): 9783662156384 Издательство: Springer Рейтинг: Цена: 36570.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is intended for non-specialists and students, presenting a unique introduction to the field of DNA nanotechnology. The primary focus is on the extraordinary advantages of specificity and sensitivity obtained by integrating DNA nanostructures in bioanalytical devices.DNA Nanotechnology for Bioanalysis provides a concise and rigorous description for the fabrication of various types of functional nanostructures by optimized software-aided high-yield synthesis. Following this is the explanation of methods to decorate these nanostructures with molecules such as proteins, metal nanoparticles or bioorganic moieties covalently bonded onto DNA via self-assemblage processes. Also provided is a concise review on non-canonical DNA structures (such as G-quadruplexes) and their targeting by small molecules for applications in pharmacology. Finally, it describes the exciting applications of DNA nanostructures in life sciences and nanomedicine, including ultraspecific molecular delivery, control of cell behavior, analysis of cell lysate and DNA-based nano-tools for super-resolution sub-cellular imaging.
Автор: Bernhard Sonnleitner Название: Bioanalysis and Biosensors for Bioprocess Monitoring ISBN: 3540660526 ISBN-13(EAN): 9783540660521 Издательство: Springer Рейтинг: Цена: 45712.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With contributions by numerous experts
Автор: Wenkui Li, Wenying Jian, Yunlin Fu Название: Sample Preparation in LC–MS Bioanalysis ISBN: 111927429X ISBN-13(EAN): 9781119274292 Издательство: Wiley Рейтинг: Цена: 22168.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Revised and Expanded Handbook Provides Comprehensive Introduction and Complete Instruction for Sample Preparation in Vital Category of Bioanalysis
Following in the footsteps of the previously published Handbook of LC-MS Bioanalysis, this book is a thorough and timely guide to all important sample preparation techniques used for quantitative Liquid Chromatography-Mass Spectrometry (LC-MS) bioanalysis of small and large molecules. LC-MS bioanalysis is a key element of pharmaceutical research and development, post-approval therapeutic drug monitoring, and many other studies used in human healthcare.
While advances are continually being made in key aspects of LC-MS bioanalysis such as sensitivity and throughput, the value of research/study mentioned above is still heavily dependent on the availability of high-quality data, for which sample preparation plays the critical role. Thus, this text provides researchers in industry, academia, and regulatory agencies with detailed sample preparation techniques and step-by-step protocols on proper extraction of various analyte(s) of interest from biological samples for LC-MS quantification, in accordance with current health authority regulations and industry best practices. The three sections of the book with a total of 26 chapters cover topics that include:
Current basic sample preparation techniques (e.g., protein precipitation, liquid-liquid extraction, solid-phase extraction, salting-out assisted liquid-liquid extraction, ultracentrifugation and ultrafiltration, microsampling, sample extraction via electromembranes)
Crucial aspects of LC-MS bioanalytical method development (e.g., pre-analytical considerations, derivation strategies, stability, non-specific binding) in addition to sample preparation techniques for challenging molecules (e.g., lipids, peptides, proteins, oligonucleotides, antibody-drug conjugates)
Sample Preparation in LC-MS Bioanalysis will prove a practical and highly valuable addition to the reference shelves of scientists and related professionals in a variety of fields, including pharmaceutical and biomedical research, mass spectrometry, and analytical chemistry, as well as practitioners in clinical pharmacology, toxicology, and therapeutic drug monitoring.
Описание: Based on the proceedings of the forum on [title]. Discusses eicosanoids and related analytes, antiflammatory drugs, cardiovascular drugs, ace inhibitors and calcium antagonists as well as detection, identification, and instrumentation. Extensive use of drawings and graphs. Annotation copyright Book News, Inc. Portland, Or.
Описание: the hallowed GC term `FID` means free induction decay to NMR practi tione:ts, who may pardon the term `Fid` as introduced editorially.
Автор: Patel, Bhavik A. (reader In Clinical Bioanalytical Chemistry, Centre For Stress And Age-related Diseases, University Of Brighton, Uk) Название: Electrochemistry for bioanalysis ISBN: 0128212039 ISBN-13(EAN): 9780128212035 Издательство: Elsevier Science Рейтинг: Цена: 29476.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Electrochemistry for Bioanalysis provides a comprehensive understanding of the benefits and challenges of the application of electrochemical and electroanalytical techniques for measurement in biological samples. The book presents detailed information on measurement in a host of various biological samples from single cells, tissues and in vivo. Sections cover real insights surrounding key experimental design and measurement within multiple complex biological environments. Finally, users will find discussions on emerging topics such as electrogenerated chemiluminescence and the use of additive manufacturing for biosensor fabrication. Continuous learning reinforcement throughout the book, including problems for self-assessment, make this an ideal resource.
Автор: Q. Alan Xu; Timothy L. Madden Название: LC-MS in Drug Bioanalysis ISBN: 1489990895 ISBN-13(EAN): 9781489990891 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Internal standards for quantitative LC-MS bioanalysis.- Method development, validation and sample analysis for regulated quantitative bioanalysis using LC-MS/MS.- Impact of sampling paper/cards on bioanalytical quantitation via dried blood spots by liquid chromatography - mass spectrometry.- Highly sensitive pharmaceutical and clinical analysis using selective solid-phase extraction coupled to microflow liquid chromatography and isotope-dilution mass spectrometry.- Pitfalls of LC-MS/MS in the clinical laboratory.- Therapeutic drug monitoring to support clinical pharmacogenomics.- Liquid chromatography - mass spectrometry for the determination of antidepressants and some of their major metabolites in human biological matrices.- The analysis of antipsychotic drugs in human biosamples by LC-MS.- Therapeutic drug monitoring of targeted anticancer therapy - tyrosine kinase inhibitors and selective oestrogen receptor modulators: a clinical pharmacology laboratory perspective.- Applications of mass spectrometry in analyses of steroid hormones.- Liquid chromatography - mass spectrometric analysis of tropane alkaloids in mammalian samples: techniques and applications.- Analysis of illicit drugs in human biological samples by LC-MSn.- Use of matrix assisted laser desorption/ionization imaging mass spectrometry (MALDI-IMS) in the development of novel small molecule drugs.- A planar integrated micro mass spectrometer.
Автор: Stephen J Meltzer Название: PCR in Bioanalysis ISBN: 1617370525 ISBN-13(EAN): 9781617370526 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Examines the evolution of US federal education policy and outlines a bold and controversial vision for its future. Jack Jennings offers a vivid analysis of federal efforts in the education arena and reveals some of the factors that shaped their enactment. His rich descriptions and lively anecdotes provide pointed lessons about the partisan climate that stymies much federal policy making today.
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