Автор: Senthilkumar Rajagopal; Murugavel Ponnusamy Название: Metabotropic GPCRs: TGR5 and P2Y Receptors in Health and Diseases ISBN: 9811315701 ISBN-13(EAN): 9789811315701 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book will provide current understandings about two ubiquitously expressed metabotropic GPCRs, G-coupled purinoreceptor type 2 (P2Y) and Takeda G-protein-coupled bile acid receptor 5 (TGR5). G protein coupled receptors (GPCRs) are the largest family of proteins implicated in majority of cellular responses. The two receptor sub-families play a central role in many physiological functions as well as in many pathological conditions. This book offers up-to-date information on the physiological functions, signaling pathways and regulatory mechanisms of P2Y and TGR5 receptors. In addition, this book provides a comprehensive overview about the abnormalities of P2Y/TGR5 receptors and their contribution in the development and progression of pathological conditions. It also covers the currently available natural, chemical and pharmacological agents targeting these two receptor families and their therapeutic implications in P2Y and TGR5 associated disorders. This book is a valuable source for beginners and researchers to follow the rapidly progressing field of these two GPCR subfamily members.
Автор: Andrea Strasser; Hans-Joachim Wittmann Название: Modelling of GPCRs ISBN: 9401780919 ISBN-13(EAN): 9789401780919 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This practical introduction to molecular modelling of GPCRs covers core principles, and moves on to present advanced GPCR modelling techniques. Includes data on crystal structures and essential amino acid sequences, as well as LINUX commands and examples.
Описание: Offers an insight into the approaches taken by industry and academia to address GPCRs. This book reflects the actual trends in the field of GPCR research in academia and industry. It is based on the international workshop GPCRs: From Deorphanisation to Lead Structure Identification, held in Berlin in May 2006.
Автор: Dong, Chen Название: Advances In Immunology In China - Part B,145 ISBN: 0128178787 ISBN-13(EAN): 9780128178782 Издательство: Elsevier Science Рейтинг: Цена: 24423.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Advances in Immunology in China - Part B, Volume 145, the latest release in the Advances in Immunology series, presents the latest release in a long-established and highly respected publication. The book includes current developments and comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, with this release focusing on advances in immunology in China.
Автор: Marcelo G. Kazanietz Название: Protein Kinase C in Cancer Signaling and Therapy ISBN: 1617796913 ISBN-13(EAN): 9781617796913 Издательство: Springer Рейтинг: Цена: 41787.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Protein kinase C (PKC), a family of serine-threonine kinases, rocketed to the forefront of the cancer research field in the early 1980`s with its identification as an effector of phorbol esters, natural products with tumor promoting activity.
Автор: David M. Terrian Название: Cancer Cell Signaling ISBN: 1617373419 ISBN-13(EAN): 9781617373411 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Cancer Cell Signaling: Methods and Protocols brings together several such methods in cell signaling research that are scientifically grounded within the cancer biology field.
Автор: Jian-Ying Wang Название: Polyamine Cell Signaling ISBN: 1617376795 ISBN-13(EAN): 9781617376795 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Polyamines are organic cations found in all eukaryotic cells and intimately involved in, and required for, distinct biological functions. An increasing body of evidence indicates that the regulation of cellular polyamines is a central convergence point for the multiple signaling pathways driving various cellular functions. Over the last decade, considerable progress has been made in und- standing the molecular functions of cellular polyamines. These significant findings provide a fundamental basis to not only define the exact role of polyamines in physiology, but also to develop new therapeutic approaches for cancers and other diseases. The major objective of this book is to provide a timely and long lasting guide for investigators in the fields of polyamines, physiology, pharmacology, and cancer research. It will provide a foundation based on research and address the potential for subsequent applications in clinical practice. Polyamine Cell Signaling: Physiology, Pharmacology, and Cancer Research is divided into four main parts: Part I: Polyamines in Signal Transduction of Cell Proliferation Part II: Polyamines in Cellular Signaling of Apoptosis, Carcinogenesis, and Cancer Therapy Part III: Polyamines in Cell Motility and Cell-Cell Interactions Part IV: Polyamine Homeostasis and Transport This book not only covers the current state-of-the-art findings relevant to cellular and molecular functions of polyamines, but also provides the underlying conceptual basis and knowledge regarding potential therapeutic targeting of polyamines and polyamine metabolism. These points are addressed by int- nationally recognized experts in their contributions to this book.
Автор: J. Silvio Gutkind Название: Signaling Networks and Cell Cycle Control ISBN: 089603710X ISBN-13(EAN): 9780896037106 Издательство: Springer Рейтинг: Цена: 36570.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Summarizes the findings on signal transduction and cell cycle regulation and describes the effort to design and synthesizes inhibiting molecules, as well as to evaluate their biochemical and biological activities. This book reviews the relevant cell surface receptors, their ligands, and their downstream pathways.
Автор: Martha Robles-Flores Название: Cancer Cell Signaling ISBN: 149394648X ISBN-13(EAN): 9781493946488 Издательство: Springer Рейтинг: Цена: 14673.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Cancer Cell Signaling: Methods and Protocols, Second Edition brings together the most recent advances in cancer cell signaling knowledge along with recent progress in the development of novel strategies and experimental cell models to study human cancer.
Описание: This book summarizes the roles, significance, and potential therapeutic targeting of transcriptional factors (TFs) from the perspective of signaling cascade. It details the physiologic and pathologic roles of TFs in specific representative organ systems.
Автор: Moshe Oren; Yael Aylon Название: The Hippo Signaling Pathway and Cancer ISBN: 1493901095 ISBN-13(EAN): 9781493901098 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: ГЇВїВЅ ГЇВїВЅ This book ГЇВїВЅ explores virtually all aspects of tumor biology in relation to the Hippo Pathway. It gathers wide-ranging and burgeoning information into an accessible format and features timely research from leading scientists in the field.
Автор: Daniel Johnson Название: Cell Death Signaling in Cancer Biology and Treatment ISBN: 1493901079 ISBN-13(EAN): 9781493901074 Издательство: Springer Рейтинг: Цена: 20896.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Discussing both preclinical and clinical approaches to targeted attacks on tumor cells, this is a key contribution to the fight against cancer, sharing cutting-edge research on the molecular and biological processes regulating cell death in malignant tumors.
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru
