Описание: Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Offering a comprehensive overview of the diagnostic surgical pathology, cytopathology, immunohistochemistry and molecular genetics of the thyroid diseases, this updated reference now incorporates recent, groundbreaking studies and major changes in the field. Global experts provide a complete guide to all diagnoses alongside major advances in tumor staging, immunohistochemistry and molecular genetics, helping you effectively evaluate thyroid tumors and non-neoplastic diseases.
Features nearly 1,200 high-quality, full-color gross photographs, microphotographs, and illustrations throughout.
Includes three new chapters to keep you completely up to date:
Noninvasive Follicular Thyroid Neoplasm with Papillary-like Nuclear Features (NIFTP)
Thyroid Tumor Staging (with new AJCC staging system)
Principles of Cytological Examination of Thyroid Nodules (with new Bethesda 2 Reporting system)
Enrich Your eBook Reading Experience with Enhanced Video, Audio and Interactive Capabilities
Read directly on your preferred device(s), such as computer, tablet, or smartphone
Easily convert to audiobook, powering your content with natural language text-to-speech
Adapt for unique reading needs, supporting learning disabilities, visual/auditory impairments, second-language or literacy challenges, and more
Автор: T. Brown Название: Genomes 4 ISBN: 0815345089 ISBN-13(EAN): 9780815345084 Издательство: Taylor&Francis Рейтинг: Цена: 9645.00 р. Наличие на складе: Поставка под заказ.
Описание:
Genomes 4 has been completely revised and updated. It is a thoroughly modern textbook about genomes and how they are investigated. As with Genomes 3, techniques come first, then genome anatomies, followed by genome function, and finally genome evolution. The genomes of all types of organism are covered: viruses, bacteria, fungi, plants, and animals including humans and other hominids.
Genome sequencing and assembly methods have been thoroughly revised including a survey of four genome projects: human, Neanderthal, giant panda, and barley. Coverage of genome annotation emphasizes genome-wide RNA mapping, with CRISPR-Cas 9 and GWAS methods of determining gene function covered. The knowledge gained from these techniques forms the basis of the three chapters that describe the three main types of genomes: eukaryotic, prokaryotic (including eukaryotic organelles), and viral (including mobile genetic elements). Coverage of genome expression and replication is truly genomic, concentrating on the genome-wide implications of DNA packaging, epigenome modifications, DNA-binding proteins, non-coding RNAs, regulatory genome sequences, and protein-protein interactions. Also included are applications of transcriptome analysis, metabolomics, and systems biology. The final chapter is on genome evolution, focusing on the evolution of the epigenome, using genomics to study human evolution, and using population genomics to advance plant breeding. Established methods of molecular biology are included if they are still relevant today and there is always an explanation as to why the method is still important.
Each chapter has a set of short-answer questions, in-depth problems, and annotated further reading. There is also an extensive glossary. Genomes 4 is the ideal text for upper level courses focused on genomes and genomics.
Автор: Craig, Nancy (professor, Department Of Molecular Biology And Genetics, Johns Hopkins University School Of Medicine) Green, Rachel (professor, Departme Название: Molecular biology ISBN: 0198788657 ISBN-13(EAN): 9780198788652 Издательство: Oxford Academ Рейтинг: Цена: 11245.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A fresh, distinctive approach to the teaching of molecular biology. With its focus on key principles, its emphasis on the commonalities that exist between the three kingdoms of life, and its integrated coverage of experimental methods and approaches, Molecular Biology is the perfect companion to any molecular biology course.
Автор: Strachan Название: Human Molecular Genetics ISBN: 0815345895 ISBN-13(EAN): 9780815345893 Издательство: Taylor&Francis Рейтинг: Цена: 12095.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Human Molecular Genetics has been carefully crafted over successive editions to provide an authoritative introduction to the molecular aspects of human genetics, genomics and cell biology.
Maintaining the features that have made previous editions so popular, this fifth edition has been completely updated in line with the latest developments in the field. Older technologies such as cloning and hybridization have been merged and summarized, coverage of newer DNA sequencing technologies has been expanded, and powerful new gene editing and single-cell genomics technologies have been added. The coverage of GWAS, functional genomics, stem cells, and disease modeling has been expanded. Greater focus is given to inheritance and variation in the context of populations and on the role of epigenetics in gene regulation.
Key features:
Fully integrated approach to the molecular aspects of human genetics, genomics, and cell biology
Accessible text is supported and enhanced throughout by superb artwork illustrating the key concepts and mechanisms
Summary boxes at the end of each chapter provide clear learning points
Annotated further reading helps readers navigate the wealth of additional information in this complex subject and provides direction for further study
Reorganized into five sections for improved access to related topics
Also new to this edition - brand new chapter on evolution and anthropology from the authors of the highly acclaimed Human Evolutionary Genetics
A proven and popular textbook for upper-level undergraduates and graduate students, the new edition of Human Molecular Genetics remains the 'go-to' book for those studying human molecular genetics or genomics courses around the world.
Автор: Domingo, Esteban Название: Rna genetics ISBN: 0367657465 ISBN-13(EAN): 9780367657468 Издательство: Taylor&Francis Рейтинг: Цена: 7195.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book describes the basic features of virus replication, and points out how these features lead into the diverse biologies and genetics of the various viruses.
Название: Molecular Biology and Genetics of the Lepidoptera ISBN: 1138111724 ISBN-13(EAN): 9781138111721 Издательство: Taylor&Francis Рейтинг: Цена: 12248.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Numerous and charismatic, the Lepidoptera is one of the most widely studied groups of invertebrates. Advances in molecular tools and genomic techniques have reduced the need for large sizes and mass-rearing, and lepidopteran model systems are increasingly used to illuminate broad-based experimental questions as well as those peculiar to butterflies and moths. Molecular Biology and Genetics of the Lepidoptera presents a wide-ranging collection of studies on the Lepidoptera, treating them as specialized insects with distinctive features and as model systems for carrying out cutting-edge research. Leading researchers provide an evolutionary framework for placing moths and butterflies on the Tree of Life.
The book covers progress in deciphering the silkworm genome and unraveling lepidopteran sex chromosomes. It features new information on sex determination, evolution, and the development of butterfly wing patterns, eyes, vision, circadian clocks, chemoreceptors, and sexual communication. The contributors discuss the genetics and molecular biology of plant host range and prospects for controlling the major crop pest genus Helicoverpa. They also explore the rise of insecticide resistance, the innate immune response, lepidopteran minihosts for testing human pathogens and antibiotics, and the use of intrahemocoelic toxins for control. The book concludes with coverage of polyDNA virus-carrying parasitoid wasps, and the cloning of the first virus resistance gene in the silkworm.
Understanding the biology and genetics of butterflies and moths may lead to new species-selective methods of control, saving billions of dollars in pesticide use and protecting environmental and human health--making the sections on strategies for pest management extremely important. This book will open up new paths to the research literature for a broad audience, including entomologists, evolutionary and systematic biologists, geneticists, physiologists, biochemists, and molecular biologists.
Автор: Rolf H. J. Schlegel Название: Rye: Genetics, Breeding, and Cultivation ISBN: 1466561432 ISBN-13(EAN): 9781466561434 Издательство: Taylor&Francis Рейтинг: Цена: 29093.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Owing to its considerable winter hardiness, rye is a cereal that played a major role in the feeding of European populations throughout the Middle Ages. Recent data shows that rye is grown on about 5.4 million hectares, with a world production of approximately 13 million tons. While still an important bread food in many countries, rye produced for bread making has decreased or stagnated, whereas production is increasing for other market segments. Particularly, rye for feeding, ethanol processing, and biogas is promoted in Europe.
The first comprehensive monograph on rye, Rye: Genetics, Breeding, and Cultivation gathers all the relevant and historic information from botany and genetics to utilization and sustainability of rye. The book covers taxonomy, morphology, and other botany-related aspects of rye. It describes its physiology, cytology, and genetics, including use for genetic improvement of other cereals. The author addresses various types of breeding such as population, hybrid, and molecular breeding. He also discusses rye cropping, including seeding techniques, fungal and viral diseases, and predators. The book examines the various uses for rye beyond bread making. This includes feeding, biomass and biogas production, ethanol production, and other important characteristics such as phytosterol content and antioxidant activity. It also explores the nutritional value of rye. Written by a leading expert in the field, this monograph compiles the most important facets of rye research, past and present.
Описание: Lecture provides an overview of the progress made in molecular medicine applying genetics and genomics to the understanding, diagnosis, and treatment of human diseases. Specifically, the methods for identifying genes involved in human diseases are described. Examples from 10 genes and diseases will be provided, drawing on the author's research. Topics include examples from simple Mendelian diseases, such as cystic fibrosis, inherited cancers, oncogenes activated by chromosomal translocations, host genes involved in infectious disease, genes identified via genomewide association studies, pathogens causing cancer, and gene families contributing to multiple diseases. For each example, historical details will be provided as background for readers to understand the context and process of the discoveries, technologies explained, and current understanding and treatment implications detailed.
Автор: Vologodskii Название: Revival: Topology and Physics of Circular DNA (1992) ISBN: 1138562815 ISBN-13(EAN): 9781138562813 Издательство: Taylor&Francis Рейтинг: Цена: 6123.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Topology and Physics of Circular DNA presents comprehensive coverage of the physical properties of circular DNA. The author examines how topological constraints arising from cyclization of DNA lead to distinctive properties that make closed molecules radically different from linear DNA.
This title includes a number of Open Access chapters.
This new volume on gene expression and epigenetics discusses environmental effects related to specific gene expression. The book also shows methods for bioinformatic analysis of the epigenome. The book is broken into two sections: the first looks at eukaryotic DNA methylation and the second addresses how to integrate genomic medicine into clinical practice.
The book includes chapters on these topics:
- Gene expression in colon cancer tissue
- Epigenetics in human acute kidney injury
- Embryologically relevant candidate genes in MRKH patients
- DNA methylation in common skeletal disorders
- Causal relationships in genomics
- Predicting severe asthma exacerbations in children
- Epigenetic understanding of gene-environment interactions in psychiatric disorders
Автор: Gerhard Gross Название: Stem Cell-dependent Therapies ISBN: 3110298260 ISBN-13(EAN): 9783110298260 Издательство: Walter de Gruyter Цена: 31603.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Multipotent mesenchymal stem cells (MSCs) are a heterogeneous population of cells which reside in a variety of tissues. They differentiate into several mesodermal lineages, secrete a multitude of trophic factors and contribute to tissue homeostasis. MSCs are able to exert immunosuppressive activities by interfering with inflammatory cytokine production and with T- and B-cell proliferation. These immunomodulating properties make MSCs promising candidates for the treatment of chronic inflammatory and autoimmune disorders. There are, however, certain caveats involved including inappropriate migration of cells in the body, immune rejection, tumor formation, or graft versus host disease (GvHD). This book investigates the current state of the MSC-dependent therapy of chronic inflammatory disorders and autoimmune diseases. Among the covered topics are GvHD, chronic kidney, liver and lung disease, ischemic heart and inflammatory bowel disease, diabetes, osteoarthritis, various rheumatic and neurological disorders and, lastly, tumors and solid organ transplantations. This book also questions the immunoprivileged status of MSCs, discusses the therapeutic role of MSCs in experimental animal disease models and their translation to the corresponding human disorders, envisions a role for MSCs in tumor interventions and, lastly, describes a systems biology approach for stem cells and inflammation.
Описание: Provides an overview of the progress made in molecular medicine applying genetics and genomics to the understanding, diagnosis, and treatment of human diseases. Specifically, the methods for identifying genes involved in human diseases are described. Examples from 10 genes and diseases are provided, drawing on the author`s research.
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru
