Vaccines: Operation Warp Speed, Regulation and Safety, Oliver Huerta

Автор: Larry J. Anderson; Barney S. Graham
Название: Challenges and Opportunities for Respiratory Syncytial Virus Vaccines
ISBN: 364238918X ISBN-13(EAN): 9783642389184
Издательство: Springer
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Цена: 27950.00 р.
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Описание: Although respiratory syncytial virus (RSV) has been a high priority for vaccine development for over 50 years now, still no vaccine is available and none has yet demonstrated sufficient promise to move to licensure.

Автор: Jacqueline MacDonald
Название: Prospects of Plant-Based Vaccines in Veterinary Medicine
ISBN: 3030079414 ISBN-13(EAN): 9783030079413
Издательство: Springer
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Цена: 20962.00 р.
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Описание:

Автор: Manmohan Singh
Название: Novel Immune Potentiators and Delivery Technologies for Next Generation Vaccines
ISBN: 1489992286 ISBN-13(EAN): 9781489992284
Издательство: Springer
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Цена: 28732.00 р.
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Описание: This book outlines the critical steps that need to be considered for successful development of various types of nanoparticulate delivery systems for vaccine antigens. Coverage includes clinical evaluations with these novel vaccine technologies.

Название: Cancer Vaccines
ISBN: 0367387557 ISBN-13(EAN): 9780367387556
Издательство: Taylor&Francis
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Описание:

Recent advances in immunology and biology have opened new horizons in cancer therapy, included in the expanding array of cancer treatment options, which are immunotherapies, or cancer vaccines, for both solid and blood borne cancers. Cancer Vaccines: Challenges and Opportunities in Translation is the first text in the field to bring immunotherapy treatments from the laboratory trial to the bedside for the practicing oncologist.

Cancer Vaccines: Challenges and Opportunities in Translation:

• Critically analyzes the most promising classes of investigational immunotherapies, integrating their scientific rationale and clinical potential
• Discusses theranostics as pertaining to immunotherapy, i.e., using molecular diagnostics to identify patients that would most likely benefit from a therapy
• Presents the new paradigm of biomarker guided R&D and clinical development in immunotherapy of cancer
• Reviews bottlenecks in translational process of immunotherapies and offers strategies to resolve them

Автор: Michael J.P. Lawman; Patricia D. Lawman
Название: Cancer Vaccines
ISBN: 1493951955 ISBN-13(EAN): 9781493951956
Издательство: Springer
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Цена: 21661.00 р.
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Описание:

Part I: Manipulation and Modification of Immune Cells: Dendritic Cells

1. Single Step Antigen Loading and Maturation of Dendritic Cells Through mRNA Electroporation of a Tumor-Associated Antigen and a TriMix of Costimulatory Molecules

Daphnй Benteyn, An M.T. Van Nuffel, Sofie Wilgenhof, and Aude Bonehill

2. Generation of Multiple Peptide Cocktail-Pulsed Dendritic Cells as a Cancer Vaccine

Hyun-Ju Lee, Nu-Ri Choi, Manh-Cuong Vo, My-Dung Hoang, Youn-Kyung Lee, and Je-Jung Lee

3. Pulsing Dendritic Cells with Whole Tumor Cell Lysates

Laura Alaniz, Manglio M. Rizzo, and Guillermo Mazzolini

4. Antigen Trapping by Dendritic Cells for Anti-Tumor Therapy

Chiranjib Pal

5. Ex Vivo Loading of Autologous Dendritic Cells with Tumor Antigens

Manglio M. Rizzo, Laura Alaniz, and Guillermo Mazzolini

6. Tumor Antigen/Cytokine-Pulsed Dendritic Cells in Therapy Against Lymphoma

Sumit K. Hira, Deepak Verma, and Partha P. Manna

7. Dendritic Cells Primed with Protein-Protein Fusion Adjuvant

Liying Wang and Yongli Yu

8. Antigen-Specific mRNA Transfection of Autologous Dendritic Cells

Fabian Benencia

9. Electroporation of Dendritic Cells with Autologous Total RNA from Tumor Material

Francesca Milano and K.K. Krishnadath

10. Dendritic Cells Transfected with Adenoviral Vectors as Vaccines

Joseph Senesac, Dmitry Gabrilovich, Samuel Pirruccello, and James E. Talmadge

11. Genetic Modification of Dendritic Cells with RNAi

Xiao-Tong Song

12. Fast Monocyte-Derived Dendritic Cells-Based Immunotherapy

Gamal Ramadan

13. Intratumoral Injection of BCG-CWS Pretreated Dendritic Cells Following Tumor Cryoablation

Naoshi Kawamura, Masaru Udagawa, Tomonobu Fujita, Toshiharu Sakurai, Tomonori Yaguchi, and Yutaka Kawakami

14. Exploiting the CD1d-iNKT Cell Axis for Potentiation of DC-Based Cancer Vaccines

Roeland Lameris, Famke L. Schneiders, Tanja D. de Gruijl, and Hans J. van der Vliet

Part II: Manipulation and Modification of Immune Cells: T Lymphocytes and NK Cells

15. Modification of T Lymphocytes to Express Tumor Antigens

Aaron E. Foster and Xiao-Tong Song

16. Genetic Modification of Mouse Effector and Helper T Lymphocytes Expressing a Chimeric Antigen Receptor

Liza B. John, Tess M. Chee, David E. Gilham, and Phillip K. Darcy

17. Genetic Modification of Cytotoxic T Lymphocytes to Express Cytokine Receptors

Serena K. Perna, Barbara Savoldo, and Gianpietro Dotti

18. Monitoring the Frequency and Function of Regulatory T Cells and Summary of the Approaches Currently Used to Inhibit Regulatory T Cells in Cancer Patients

Chiara Camisaschi, Marcella Tazzari, Licia Rivoltini, and Chiara Castelli

19. Cytokine Activation of Natural Killer Cells

Syh-Jae Lin, Pei-Tzu Lee, and Ming-Ling Kuo

Part III: Manipulation and Modification of Tumor Cells

20. Loading of Acute Myeloid Leukemia Cells with Poly(I: C) by Electroporation

Eva Lion, Charlotte M. de Winde, Viggo F.I. Van Tendeloo, and Evelien L.J.M. Smits

21. Autologous Tumor Cells Engineered to Express Bacterial Antigens

Vijayakumar K. Ramiya, Maya M. Jerald, Patricia D. Lawman, and Michael J.P. Lawman

22. Tumor Cell Transformation Using Antisense Oligonucleotide

Mohamed R. Akl and Nehad M. Ayoub

23. The Direct Display of Costimulatory Proteins on Tumor Cells as a Means of Vaccination for Cancer Immunotherapy

Haval Shirwan, Esma S. Yolcu, Rajesh K. Sharma, Hong Zaho, and Orlando Grimany-Nuno

Part IV: Manipulation of Immune/Tumor Interactions

24. Cloning Variable

Автор: Kalkum Markus, Semis Margarita
Название: Vaccines for Invasive Fungal Infections: Methods and Protocols
ISBN: 1493983857 ISBN-13(EAN): 9781493983858
Издательство: Springer
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Цена: 22359.00 р.
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Описание: This detailed volume focuses on the development of mycosis vaccines via the most common etiological agents of mycoses, such as Aspergillus and Candida species, followed by Cryptococcus, dimorphic fungi, and members of Mucoraceae family of fungi.

Автор: Guo
Название: Carbohydrate-Based Vaccines
ISBN: 0470197560 ISBN-13(EAN): 9780470197561
Издательство: Wiley
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Цена: 22168.00 р.
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Описание: Synthetic carbohydrate-based vaccines, including polysaccharides, neoglycoproteins, and neoglycolipids, have been explored to prevent and treat bacterial and viral infections, cancer, and other diseases. This book discusses these developments with a focus on glycoimmunology including the design, synthesis, and applications of these vaccines.

Автор: Andrew W. Artenstein
Название: Vaccines: A Biography
ISBN: 1489983627 ISBN-13(EAN): 9781489983626
Издательство: Springer
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Цена: 23058.00 р.
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Описание: Why another book about vaccines? There are already a few extremely well-written medical textbooks that provide comprehensive, state-of-the-art technical reviews regarding vaccine science. Additionally, in the past decade alone, a number of engrossing, provocative books have been published on various related issues ra- ing from vaccines against specific diseases to vaccine safety and policy. Yet there remains a significant gap in the literature – the history of vaccines. Vaccines: A Biography seeks to fill a void in the extant literature by focusing on the history of vaccines and in so doing, recounts the social, cultural, and scientific history of vaccines; it places them within their natural, historical context. The book traces the lineage – the “biography” – of individual vaccines, originating with deeply rooted medical problems and evolving to an eventual conclusion. Nonetheless, these are not “biographies” in the traditional sense; they do not trace an individual’s growth and development. Instead, they follow an idea as it is conceived and dev- oped, through the contributions of many. These are epic stories of discovery, of risk-takers, of individuals advancing medical science, in the words of the famous physical scientist Isaac Newton, “by standing on the shoulders of giants. ” One grant reviewer described the book’s concept as “triumphalist”; although meant as an indictment, this is only partially inaccurate.

Автор: Philip R. Dormitzer; Christian W. Mandl; Rino Rapp
Название: Replicating Vaccines
ISBN: 3034803168 ISBN-13(EAN): 9783034803168
Издательство: Springer
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Цена: 28732.00 р.
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Описание: Currently, we are witnessing a quantum leap in our technological capabilities to specifically modify the genetic make-up of viruses and bacteria, making it possible to generate improved live vaccines and to develop completely new types of replicating vaccines, such as vectored vaccines, single-round infectious vaccines and replicon vaccines.

Автор: Douglas B. Lowrie; Robert Whalen
Название: DNA Vaccines
ISBN: 0896035808 ISBN-13(EAN): 9780896035805
Издательство: Springer
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Цена: 28732.00 р.
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Описание: This collection of review articles summarize how to develop and employ DNA vaccines, what can be expected from their clinical development, and what is known about how they work. Topics include immunostimulatory sequences, cytokines, and practical advice for general and specific applications.

Автор: Linqi Zhang; Sharon R. Lewin
Название: HIV Vaccines and Cure
ISBN: 9811344280 ISBN-13(EAN): 9789811344282
Издательство: Springer
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Цена: 20962.00 р.
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Описание: This book provides a comprehensive review of the major barriers to HIV cure and vaccine. It covers the fundamental virology and immunology leading to HIV transmission, protection from infection and long term HIV persistence on antiretroviral therapy. In addition, strategies being tested to eliminate persistent HIV and the rational design of vaccines to induce protective immunity are covered. This book also discusses the challenges related to the design of clinical trials for testing the safety and efficacy of these innovative approaches. This book will provide a systematic overview and also discuss controversial issues for researchers in virology and immunology, as well as practicing physicians, and scientists in the pharmaceutical industry.

Автор: Rudolf Valenta; Robert L. Coffman
Название: Vaccines against Allergies
ISBN: 3642271006 ISBN-13(EAN): 9783642271007
Издательство: Springer
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Цена: 26120.00 р.
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Описание: Vaccines against Allergies celebrates the one hundred year anniversary of allergen-specific immunotherapy. Today allergen-specific immunotherapy is well established as the only allergen-specific and disease-modifying treatment for IgE-mediated allergies and has long-lasting effects.