Myeloid Leukemia: Methods and Protocols, Iland Harry, Hertzberg Mark, Marlton Paula
Автор: Michael Andreeff Название: Targeted Therapy of Acute Myeloid Leukemia ISBN: 1493913921 ISBN-13(EAN): 9781493913923 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides an unprecedented overview of "Targeted Therapies" for acute myeloid leukemias. It aims at an almost comprehensive coverage of the diverse therapeutic strategies that have been developed during the last decade and are now being evaluated in early clinical trials. Paired and authoritative chapters by leading research scientists and clinicians explain basic concepts and clinical translation of topics that include the underlying genetic and proteomic abnormalities of AML, the development of novel nucleoside analogues, the roles of microRNAs, apoptosis regulators Bcl-2 and p53 and of critical cell signaling proteins such as PIM, FLT3, Raf/MEK, PI3K/AKT/mTOR and aurora kinases. Chapters on epigenetic mechanisms, nuclear receptors, cell surface antigens, the hypoxic leukemia microenvironment, stem cells and leukemia metabolism provide insights into leukemia cell vulnerabilities. Cell therapies utilizing T-, NK- and mesenchymal stem cells and progress in hematopoietic transplantation strategies round up this overview of the multi-dimensional therapeutic landscape in which leukemia specialists develop treatment strategies that are expected to make "leukemia history" in the near future.
Описание: Provides information about the current status of aclacinomycin A for the treatment of haematologic malignancies. The text includes accounts of the action of aclacinomycin A in myelodysplastic syndromes and of its efficacy in acute myeloid leukemias.
Автор: Paolo Fortina; Eric Londin; Jason Y. Park; Larry J Название: Acute Myeloid Leukemia ISBN: 1493971409 ISBN-13(EAN): 9781493971404 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume describes up-to-date techniques used in understanding the molecular biology of acute myeloid leukemia (AML) and addressing advances in diagnosis, classification, prognostication, and therapeutic strategies to potentially impact overall patient survival.
Автор: Richard Greil; Lisa Pleyer; Daniel Neureiter; Vikt Название: Chronic Myeloid Neoplasias and Clonal Overlap Syndromes ISBN: 3709120039 ISBN-13(EAN): 9783709120033 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Introduction The understanding of the genetic, epigenetic, immuno- well as for practicing hematologists or oncologists. logical and biological causes of myeloproliferative dis- Each chapter follows a similar architecture and leads orders has substantially improved in the last few years. through epidemiology, genetic and molecular causes, Together with refined tools in pathology, the successful hematological and clinical findings, prognostic factors establishment of mouse models mimicking at least some and current treatment approaches of the diseases. of the myeloproliferative disorders, and murine models Effort has been made to point out the evolving field of novel drugs in this arena but simultaneously diff- allowing to carefully dissect the role of mutations and gene dosage effects of, for example JAK2, this has led to entiate between standard and experimental treatment ever increasing numbers of modified classification approaches. schemes. It is therefore important for the heamtologist Together with the co-editors and all the authors of or oncologist to keep up with this rapid change in classi- the various chapters I hope that the readers of the book fication language, the upcoming of new entities or differ- will enjoy reading and benefit from the information entiation between, or subclassification of, rare diseases provided.
Автор: Chung-Che (Jeff) Chang; Robert S. Ohgami Название: Precision Molecular Pathology of Myeloid Neoplasms ISBN: 3319621440 ISBN-13(EAN): 9783319621449 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Written by experts in the field, Precision Molecular Pathology of Myeloid Neoplasms serves as a valuable resource for pathologists, hematologists/oncologists, fellows, and researchers in understanding the molecular pathology of myeloid neoplasms.
Автор: Carella Название: Chronic Myeloid Leukaemia ISBN: 185317890X ISBN-13(EAN): 9781853178900 Издательство: Informa Рейтинг: Цена: 15886.00 р. Наличие на складе: Нет в наличии.
Описание: Drawing on the expertise of an international team of experts in chronic myeloid leukemia, this book provides insight into the latest advances and the implications those developments have for management of the disease. The editors and their panel of contributors explore many topics, including a review of molecular and cellular biology, a discussion of conventional chemotherapy and interferon therapy, and recent developments in allografting and autografting. The reader gains not only an incisive view of the biological structure of the disease, but applications of that biology to treatment modalities. The book emphasizes treatment strategies and is a guide to complex treatment options.
Автор: Grace L.C. Shen-Ong; Michael Potter; Neal G. Copel Название: Mechanisms in Myeloid Tumorigenesis 1988 ISBN: 364274625X ISBN-13(EAN): 9783642746253 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Kato Название: Pediatric Acute Lymphoblastic Leukemia ISBN: 9811505470 ISBN-13(EAN): 9789811505478 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Поставка под заказ.
Описание: This book discusses key aspects of childhood acute lymphoblastic leukemia (ALL), presenting the latest research on the biology and treatment of the disease and related issues.
Автор: Emadi Ashkan, Karp Judith E. Название: Acute Leukemia: An Illustrated Guide to Diagnosis and Treatment ISBN: 1620701006 ISBN-13(EAN): 9781620701003 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 18810.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Provides a comprehensive and concise visual reference on acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) seen in children and adults. This book addresses all aspects of AML and ALL including their risk factors, cytogenetics and mutational characteristics, diagnoses, clinical management and prognoses. It presents complex information relying predominantly on pictorial depictions.
Автор: R. Neth; R. C. Gallo; M. F. Greaves; M. A. S. Moor Название: Modern Trends in Human Leukemia V ISBN: 3540118586 ISBN-13(EAN): 9783540118589 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Organized on behalf of the Deutsche Gesellschaft fur Hamatologie und Onkologie, Wilsede, June 21-23, 1982
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