Molecular Profiling: Methods and Protocols, Espina Virginia
Автор: Virginia Espina Название: Molecular Profiling ISBN: 1493969897 ISBN-13(EAN): 9781493969890 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
1. Tumor Staging and Grading: A Primer
Stacy M. Telloni
2. Innovations in Clinical Trial Design in the Era of Molecular Profiling
Julia D. Wulfkuhle, Alexander Spira, Kirsten H. Edmiston, and Emanuel F. Petricoin
3. Personalized Medicine: Ethical Aspects
G. Terry Sharrer 4. Antibody Validation by Western Blotting
Michele Signore, Valeria Manganelli and Alex Hodge
5. Scanning Electron Microscopy Sample Preparation and Imaging
Jenny Ngoc Tran Nguyen and Amanda M. Harbison
Claudius Mueller, Michael G. Harpole, and Virginia Espina
7. Application of Hydrogel Nanoparticles for the Capture, Concentration, and Preservation of Low-Abundance Biomarkers
Ruben Magni and Alessandra Luchini
8. Using Laser Capture Microdissection to Isolate Cortical Laminae in Non-human Primate Brain
Brian A. Corgiatand Claudius Mueller
9. Western Blot Techniques
Brianna Kim
10. ELISA for Monitoring Nerve Growth Factor
Justin B. Davis
11. Reverse Phase Protein Microarrays
Elisa Baldelli, Valerie Calvert, Alex Hodge, Amy VanMeter, Emanuel F. Petricoin III, and Mariaelena Pierobon
12. Clustering and Network Analysis of Reverse-Phase Protein Array Data
Adam Byron
13. PCR: Identification of Genetic Polymorphisms
Amanda M. Harbison and Jenny Ngoc Tran Nguyen
14. Microsatellite Analysis for Identification of Individuals Using Bone from the Extinct Steller's Sea Cow (Hydrodamalis gigas)
Jeffery F. Warner, Michael G. Harpole, and Lorelei D. Crerar
15. Somatic DNA Mutation Analysis
Anthony O'Grady and Robert Cummins
16. Optimization of Immunostaining for Prospective Image Analysis
Scott M. Lawrence and Yelena G. Golubeva
17. Fluorescence in situ Hybridization of Cells, Chromosomes, and Formalin Fixed Paraffin Embedded Tissues
Ahmad Alamri, Jun Yeb Nam, and Jan K. Blancato
18. High-Resolution Image Stitching as a Tool to Assess Tissue-Level Protein Distribution and Localization
Bryan A. Millis and Matthew J. Tyska
19. Mass Spectrometry Based Biomarker Discovery
Weidong Zhou, Emanuel F. Petricoin III, and Caterina Longo
20. Quantitative Mass Spectrometry by Isotope-Dilution and Multiple Reaction Monitoring (MRM)
Paul Russo, Brian L. Hood, Nicholas W. Bateman, Thomas P. Conrads
21. LC-Mass Spectrometry for Metabolomics Allyson L. Dailey
22. Metabolomic Bioinformatic Analysis
Allyson L. Dailey
23. Stable Isotope Quantitative N-glycan Analysis by Liquid Separation Techniques and Mass Spectrometry
Stefan Mittermayr, Simone Albrecht, Csaba Vбradi, Silvia Millбn-Martнn, and Jonathan Bones
24. Grant Writing Tips for Translational Research
Lindsay Wescott, Michael Laskofski, Donna Senator, and Carly Curran
25. Inventions and Patents: A Practical Tutorial
Hina Mehta, Lille Tidwell, and Lance A. Liotta
26. Product Development and Commercialization of Diagnostic or Life Science Products for Scientists and Researchers
Описание: In Cellular Cardiomyoplasty: Methods and Protocols, expert researchers in the field detail many of the methods which are now commonly used to study cellular cardiomyoplasty, only adult stem cells or adult progenitor cells are included.
Автор: Nagamoto-Combs Kumi Название: Animal Models of Allergic Disease: Methods and Protocols ISBN: 1071610007 ISBN-13(EAN): 9781071610008 Издательство: Springer Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume in the Encyclopedia of Sustainability Science and Technology, Second Edition, describes the breadth of science and engineering knowledge critical to advancing sustainable built environments, from architecture and design, mechanical engineering, lighting, and materials to water and energy, public policy, and economics.
Название: Clinical proteomics: Methods and Protocols ISBN: 158829837X ISBN-13(EAN): 9781588298379 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Covers methodologies on protein profiling and identification of disease biomarkers in tissues, microdissected cells and body fluids. This book also details experimental approaches involving the application of two-dimensional electrophoresis, multi-dimensional liquid chromatography, and SELDI/MALDI mass spectrometry and protein arrays.
Описание: This volume is a compendium of cutting-edge molecular methods for the successful transplantation of hematopoietic stem cells. They describe promising tools for stem cell transplant research models, such as in vivo bioluminescence imaging. They discuss HLA typing, PCR-SSP typing, and HLA antigens.
Автор: Virginia Espina; Lance A. Liotta Название: Molecular Profiling ISBN: 1493956841 ISBN-13(EAN): 9781493956845 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Contents
Preface
Contributors
1. Tumor Staging and Grading: A Primer
Stacy M. Cowherd
2. Clinical Trial Design in the Age of Molecular Profiling
Alexander Spira and Kirsten H. Edmiston
3. Personalized Medicine: Ethics for Clinical Trials
G. Terry Sharrer
4. Reduction of Preanalytical Variability in Specimen Procurement for Molecular Profiling
Virginia Espina and Claudius Mueller
5. The Human Side of Cancer Biobanking
Eoin Gaffney, Deirdre Madden, and Geraldine A. Thomas
6. Introduction to Genomics
Luca Del Giacco and Cristina Cattaneo
7. Genomic Profiling: cDNA arrays and oligoarrays
Francesco Gorreta, Walter Carbone, Dagania Barzhagi
23. Structure-based functional design of drugs: from target to lead compound
Amy C. Anderson
24. Personalized Medicine: Changing the Paradigm of Drug Development
Robin Couch and Bryan T. Mott
25. Grant Writing Tips for the First Time Applicant
Lindsay Wescott and Michael Laskofski
26. Inventions and Patents: A practical tutorial
J. Lille Tidwell and Lance Liotta
27. Regulatory Approval Pathways for Molecular Diagnostic Technology
Lance Liotta and Emanuel Petricoin
28. Small business development for molecular diagnostics
Athanasia Anagnostou and Lance Liotta
Автор: Sarah S. Murray Название: Tumor Profiling ISBN: 1493990020 ISBN-13(EAN): 9781493990023 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides a practical guide to current methods for profiling and interpreting genomic alterations in tumors. Chapters detail methods to interrogate DNA variation, RNA expression, and epigenetic changes using both next-generation sequencing and microarray techniques, common bioinformatics and annotation tools to glean relevant driver genomic events, and different performance characteristics as well as quality metrics necessary for the robust validation of tumor profiling as a diagnostic test for medical laboratories. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Tumor Profiling: Methods and Protocols aims to be a useful resource for learning about technical details, applications, and strengths and limitations of the latest technologies as applied to this increasingly important field.
Описание: This book presents a series of protocols in multiple disease areas affected by the aging process along with several methods which have shown progress in nutrient- or intervention-based approaches to maximize the healthspan. Of interest to researchers in the areas of chronic disease, gerontology, physical exercise, and nutrition as well as to clinical scientists, physicians, and pharmacologists, this volume also provides important information on disease mechanisms and novel drug targets as each protocol will be presented in the context of specific chronic diseases or different therapeutic areas. Written for the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Clinical and Preclinical Models for Maximizing Healthspan: Methods and Protocols is an ideal guide for preclinical and clinical researchers working toward the discoveries needed to lead to a world society in which individuals are not only living longer lives but more productive and healthier ones.
Автор: Ishikawa Kiyotake Название: Cardiac Gene Therapy: Methods and Protocols ISBN: 1493982435 ISBN-13(EAN): 9781493982431 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Newer vectors and more efficient vector delivery methods have the potential to dramatically improve gene transduction efficacy, while novel gene manipulation techniques enforce the therapeutic power and broaden disease targets.
Автор: Trabalzini Lorenza, Finetti Federica, Retta Saverio Francesco Название: Cerebral Cavernous Malformations (CCM): Methods and Protocols ISBN: 1071606395 ISBN-13(EAN): 9781071606391 Издательство: Springer Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume provides experimental approaches aimed to characterize the Cerebral Cavernous Malformations (CCM) disease and to define the cellular and molecular mechanisms underlying this pathology.
Автор: Costa Cristina Название: Xenotransplantation: Methods and Protocols ISBN: 1071602543 ISBN-13(EAN): 9781071602546 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Поставка под заказ.
Автор: Lion Thomas Название: Human Fungal Pathogen Identification: Methods and Protocols ISBN: 1493982222 ISBN-13(EAN): 9781493982226 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Part I: Introductory Chapters
1. Current Challenges in the Diagnosis of Fungal Infections
Cornelia Lass-Flцrl
2. The Changing Epidemiology of Invasive Fungal Infections
David A. Enoch, Huina Yang, Sani H. Aliyu, and Christianne Micallef
3. Current Algorithms in Fungal Diagnosis in the Immunocompromised Host
Thomas Lehrnbecher, Karsten Becker, and Andreas H. Groll
4. Commercial Molecular Tests for Fungal Diagnosis from a Practical Point of View
Michaela Lackner and Cornelia Lass-Flцrl
5. Systemic Antifungal Agents: Current Status and Projected Future Developments
Seyedmojtaba Seyedmousavi, Haleh Rafati, Macit Ilkit, Mohammad T. Hedayati, and Paul Verweij
6. Fungal-Grade Reagents and Materials for Molecular Analysis
Michael G. Lorenz, Michael Lustig, and Marina Linow
Part II: Host Susceptibility and Defense
7. Host-Derived Biomarkers for Risk Assessment of Invasive Fungal Diseases
Cristina Cunha, Samuel M. Gonзalves, and Agostinho Carvalho
8. Assessment of Immune Responses to Fungal Infections: Identification and Characterization of Immune Cells in the Infected Tissue
Florian Sparber and Salomй LeibundGut-Landmann
Part III: Screening Approaches to Fungal Pathogen Detection
9. Histopathology
Renate Kain
10. Culture-Based Techniques
Birgit Willinger
11. Serological Approaches
Barbora Weinbergerova, Iva Kocmanova, Zdenek Racil, and Jiri Mayer
12. Isolation of Nucleic Acids for Fungal Diagnosis
P. Lewis White and Rosemary A. Barnes
13. Prerequisites for Control of Contamination in Fungal Diagnosis
Stefan Czurda and Thomas Lion
14. Broad-Spectrum Molecular Detection of Fungal Nucleic Acids by PCR-Based Amplification Techniques
Stefan Czurda and Thomas Lion
15. Genus- and Species-Specific PCR Detection Methods
Jan Springer and Jьrgen Lцffler
16. Identification of Fungal Pathogens in Tissue Samples from Patients with Proven Invasive Infection by Fluorescence In Situ Hybridization
Ilka McCormick Smith and Volker Rickerts
17. Nuclear Magnetic Resonance Spectroscopy-Based Identification of Yeast
Uwe Himmelreich, Tania C. Sorrell, and Heide-Marie Daniel
18. T2 Magnetic Resonance for Fungal Diagnosis
Fainareti N. Zervou, Ioannis M. Zacharioudakis, Jaclynn Kurpewski, and Eleftherios Mylonakis
Part IV: Identification of Fungal Species
19. Fungal Species Identification by MALDI-ToF Mass Spectrometry
Oliver Bader
20. Immunological Identification of Fungal Species
Filomena Nogueira, Fabian Istel, Leonel Pereira, Michael Tscherner, and Karl Kuchler
21. The Molecular Blueprint of a Fungus by Next-Generation Sequencing (NGS)
Christian Grumaz, Philipp Kirstahler, and Kai Sohn
22. Microarray Technologies in Fungal Diagnostics
Steffen Rupp
Part V: Drug Resistance Testing
23. Molecular Detection of Resistance to Echinocandins
Brunella Posteraro, Antonietta Vella, Elena De Carolis, and Maurizio Sanguinetti
24. Molecular Detection of Resistance to Azole Components
Brunella Posteraro, Antonietta Vella, Elena De Carolis, and Maurizio Sanguinetti
Part VI: Novel Experimental Approaches
25. Immune Cell-Supplemented Human Skin Model for Studying Fungal Infections
Andreas Kьhbacher, Kai Sohn, Anke Burger-Kentischer, and Steffen Rupp
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