Serum/Plasma Proteomics: Methods and Protocols, Simpson Richard J., Greening David W.

Автор: David W. Greening; Richard J. Simpson
Название: Serum/Plasma Proteomics
ISBN: 1493970569 ISBN-13(EAN): 9781493970568
Издательство: Springer
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Описание:

Part I Updated Blood Processing and Handling Strategies

1. Direct Assessment of Plasma/Serum Sample Quality for Proteomics Biomarker Investigation

Viviana Greco, Cristian Piras, Luisa Pieroni, and Andrea Urbani

2. A Protocol for the Preparation of Cryoprecipitate and Cryo-Depleted Plasma

Rosemary L Sparrow, David W Greening, and Richard J Simpson

3. A Proteomic Protocol for the Preparation of Platelet Concentrates

David W Greening, Richard J Simpson, and Rosemary L Sparrow

Part II Updated Fractionation Strategies for In-depth Blood Proteome Analysis

4. Bead-based and Multiplexed Immunoassays for Protein Profiling via Sequential Affinity Capture

Elin Birgersson, Jochen M. Schwenk, and Burcu Ayoglu

Автор: Peter B. Gahan
Название: Circulating Nucleic Acids in Plasma and Serum
ISBN: 9400790414 ISBN-13(EAN): 9789400790414
Издательство: Springer
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Описание: DNA and RNA fractions have been isolated from the whole blood, serum, plasma, the surface of blood cells, urine, saliva and spinal fluid from both healthy individuals and clinical patients. Recent developments are presented concerning the isolation, quantification and analysis of these molecules and their use in the identification of specific nucleic acid fragments related to a variety of clinical disorders thereby permitting their early diagnosis and prognosis.

Автор: Martin A. Masuelli
Название: Bovine Serum Albumin: Properties and Applications
ISBN: 1536167878 ISBN-13(EAN): 9781536167870
Издательство: Nova Science
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Описание: Serum albumin is a large protein present in cow serum protein (BSA, Bovine Serum Albumin) rich in essential amino acids and compounds with disulfide bridges and thiol groups. This protein passes into breast milk from the bloodstream by diffusion, has antioxidant capacity and protects fats from oxidation. Albumin has the ability to inhibit tumor factors and bind to fat, mobilize them in the body to perform other functions such as obtaining energy or forming membranes. It is also able to block the conversion of angiotensin I into angiotensin II (vasoconstrictor) which gives it antihypertensive action. In addition, it has the ability to reduce cholesterol absorption, complex heavy metals and is an opioid agonist (acts on opioid receptors and promotes analgesia). BSA is the most studied and produced protein worldwide in the last 80 years. This protein brings large dividends to the world economy with a very prominent and favorable annual growth at a cost of 100 USD per gram. This book brings new contributions to the science and industry of this biopolymer. The audience of this book is very wide from students, teachers and researchers (doctors, pharmacists, biochemists and industrialists of this sector). Therefore, this book has a great future and many readers to whom it is addressed.

Автор: Swaminathan
Название: Circulating Nucleic Acids in Plasma and Serum IV: Annals of the New York Academy of Sciences Volume 1075
ISBN: 157331627X ISBN-13(EAN): 9781573316279
Издательство: Wiley
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Описание: An accurate, inexpensive, and noninvasive method for the early diagnosis of cancer has been something of a holy grail among cancer researchers, but until recently a method meeting all three criteria has been elusive.