Bovine Serum Albumin: Properties and Applications, Martin A. Masuelli
Автор: Otagiri Название: Albumin in Medicine ISBN: 9811021155 ISBN-13(EAN): 9789811021152 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents a comprehensive overview of medical and pharmaceutical applications of human serum albumin (HSA), with updates on structural aspects of albumin from the perspectives of X-ray crystallography and NMR, endogenous and exogenous ligand binding of albumin in various pathological conditions, and genetic variants and their phenotypes. Rapid progress and development of its applications have resulted in outstanding results for which albumin has clearly been proven to be a robust biomaterial. Contributions from leading international experts in this field show how HSA is applied to diagnosis, therapy, drugs, and treatment, with a comprehensive introduction of HSA. This volume will appeal to scientists in pharmaceutical and medical research including pharmaceutical chemists, pharmacokineticists, toxicologists, and biochemists not only in academia but also in industry. Readers can effectively acquire the most recent knowledge of applications of HSA and its impact on human health in a single volume.
Автор: Greening David W., Simpson Richard J. Название: Serum/Plasma Proteomics: Methods and Protocols ISBN: 1493983806 ISBN-13(EAN): 9781493983803 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Part I Updated Blood Processing and Handling Strategies
1. Direct Assessment of Plasma/Serum Sample Quality for Proteomics Biomarker Investigation
Viviana Greco, Cristian Piras, Luisa Pieroni, and Andrea Urbani
2. A Protocol for the Preparation of Cryoprecipitate and Cryo-Depleted Plasma
Rosemary L Sparrow, David W Greening, and Richard J Simpson
3. A Proteomic Protocol for the Preparation of Platelet Concentrates
David W Greening, Richard J Simpson, and Rosemary L Sparrow
Part II Updated Fractionation Strategies for In-depth Blood Proteome Analysis
4. Bead-based and Multiplexed Immunoassays for Protein Profiling via Sequential Affinity Capture
Elin Birgersson, Jochen M. Schwenk, and Burcu Ayoglu
5. Affinity Proteomics for Fast, Sensitive, Quantitative Analysis of Proteins in Plasma
John P O'Grady, Kevin W Meyer, and Derrick N Poe
6. Characterization of the Low-molecular Weight Human Plasma Peptidome
David W. Greening and Richard J. Simpson
7. In-depth, Reproducible Analysis of Human Plasma using IgY 14 and SuperMix Immunodepletion
Lynn A. Beer, Bonnie Ky, Kurt T. Barnhart, and David W. Speicher
8. Low-Molecular-Weight Plasma Proteome Analysis Using Top-Down Mass Spectrometry
Dong Huey Cheon, Eun Gyeong Yang, Cheolju Lee, and Ji Eun Lee
9. Identification of Post-Translational Modifications from Serum/Plasma by Immunoaffinity Enrichment and LC-MS/MS Analysis without Depletion of Abundant Proteins
Hongbo Gu, Jianmin Ren, Xiaoying Jia, and Matthew P. Stokes
10. Identification of Core-fucosylated Glycoproteome in Human Plasma
Qichen Cao, Qing Zhao, Xiaohong Qian, and Wantao Ying
Part III Updated Proteome Analysis of Blood Cell Components, Vesicles, and Blood-related Fluids
11. Proteomic Analysis of Blood Extracellular Vesicles in Cardiovascular Disease by LC-MS/MS Analysis
Montserrat Baldan-Martin, Fernando de la Cuesta, Gloria Alvarez-Llamas, Gema Ruiz-Hurtado, Luis M. Ruilope, and Maria G. Barderas
12. Targeted Approach For Proteomic Analysis of a Hidden Membrane Protein
Tania Martins-Marques, Sandra I. Anjo, Teresa Ribeiro-Rodrigues, Bruno Manadas, and Henrique Girao
13. Red Blood Cells in Clinical Proteomics
Ana Sofia Carvalho, Manuel S Rodriguez, and Rune Matthiesen
14. High-throughput Quantitative Lipidomics Analysis of Non-esterified Fatty Acids in Plasma by LC-MS
Nicolas Christinat, Delphine Morin-Rivron, and Mojgan Masoodi
15. Simultaneous Enrichment of Plasma Extracellular Vesicles and Glycoproteome for Studying Disease Biomarkers
Sunil S. Adav and Siu Kwan Sze
16. Lipidomics of Human Blood Plasma by High Resolution Shotgun Mass Spectrometry
Susanne Sales, Oskar Knittelfelder, and Andrej Shevchenko
17. Proteomics Analysis of Circulating Serum Exosomes
Antonius Koller, Purvi Patel, Jenny Kim Kim, and Emily I. Chen
Part IV Antibody-based Discovery and Targeted Proteomics
18. High-density Serum/Plasma Reverse Phase Protein Arrays
Cecilia Hellstrцm, Tea Dodig-Crnkovic, Mun-Gwan Hong, Jochen M. Schwenk, Peter Nilsson, and Ronald Sjцberg
19. Antibody Colocalization Microarray for Cross-reactivity free Multiplexed Protein Analysis
Vйronique Laforte, Pik-Shan Lo, Huiyan Li, and David Juncker
20. Surface Profiling of Extracellular Vesicles From Plasma or Ascites Fluid using Dotscan Antibody Microarrays
Larissa Belov, Susannah Hallal, Kieran Matic, Jerry Zhou, Sandra Wissmueller, Nuzhat Ahmed, Sumaiya Tanjil, Stephen P. Mulligan, O. Giles Best, Richard J. Simpson, and Richard I. Christopherson
Автор: Simpson Richard J., Greening David W. Название: Serum/Plasma Proteomics: Methods and Protocols ISBN: 1493958011 ISBN-13(EAN): 9781493958016 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Blood science has become a cornerstone of multiple disciplines, including clinical chemistry, disease diagnosis, and therapeutic monitoring. Over the past decade, we have witnessed the advent of increasingly powerful proteomics technologies that allow greater fundamental insights into the blood proteome. These technological improvements have, in part, fuelled the quest for the discovery of novel blood-based biomarkers of disease. Serum/Plasma Proteomics: Methods and Protocols is a comprehensive resource of protocols for areas, pre-analytical through to analytical, of plasma and serum proteomics. Divided into five convenient sections, this detailed volume covers fractionation strategies for in-depth blood proteome analysis, defined procedures for blood collection, handling and storage, detailed protocols for performing both antibody-based and non-antibody based quantitative assays, proteome analysis of blood cell compartments, circulating nanomebraneous vesicles and blood-related fluids, and finally data management, statistical design, and bioinformatic challenges. This book, contributed to by leading experts in the field, provides a valuable foundation for the development and application of blood-based proteomics. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Serum/Plasma Proteomics: Methods and Protocols, with its well-honed methodologies, seeks to serve both professionals and investigators new to the field in an effort to further our knowledge of this fundamental science.
Автор: Peter B. Gahan Название: Circulating Nucleic Acids in Plasma and Serum ISBN: 9400790414 ISBN-13(EAN): 9789400790414 Издательство: Springer Рейтинг: Цена: 30606.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: DNA and RNA fractions have been isolated from the whole blood, serum, plasma, the surface of blood cells, urine, saliva and spinal fluid from both healthy individuals and clinical patients. Recent developments are presented concerning the isolation, quantification and analysis of these molecules and their use in the identification of specific nucleic acid fragments related to a variety of clinical disorders thereby permitting their early diagnosis and prognosis.
Автор: David W. Greening; Richard J. Simpson Название: Serum/Plasma Proteomics ISBN: 1493970569 ISBN-13(EAN): 9781493970568 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Part I Updated Blood Processing and Handling Strategies
1. Direct Assessment of Plasma/Serum Sample Quality for Proteomics Biomarker Investigation
Viviana Greco, Cristian Piras, Luisa Pieroni, and Andrea Urbani
2. A Protocol for the Preparation of Cryoprecipitate and Cryo-Depleted Plasma
Rosemary L Sparrow, David W Greening, and Richard J Simpson
3. A Proteomic Protocol for the Preparation of Platelet Concentrates
David W Greening, Richard J Simpson, and Rosemary L Sparrow
Part II Updated Fractionation Strategies for In-depth Blood Proteome Analysis
4. Bead-based and Multiplexed Immunoassays for Protein Profiling via Sequential Affinity Capture
Elin Birgersson, Jochen M. Schwenk, and Burcu Ayoglu
5. Affinity Proteomics for Fast, Sensitive, Quantitative Analysis of Proteins in Plasma
John P O'Grady, Kevin W Meyer, and Derrick N Poe
6. Characterization of the Low-molecular Weight Human Plasma Peptidome
David W. Greening and Richard J. Simpson
7. In-depth, Reproducible Analysis of Human Plasma using IgY 14 and SuperMix Immunodepletion
Lynn A. Beer, Bonnie Ky, Kurt T. Barnhart, and David W. Speicher
8. Low-Molecular-Weight Plasma Proteome Analysis Using Top-Down Mass Spectrometry
Dong Huey Cheon, Eun Gyeong Yang, Cheolju Lee, and Ji Eun Lee
9. Identification of Post-Translational Modifications from Serum/Plasma by Immunoaffinity Enrichment and LC-MS/MS Analysis without Depletion of Abundant Proteins
Hongbo Gu, Jianmin Ren, Xiaoying Jia, and Matthew P. Stokes
10. Identification of Core-fucosylated Glycoproteome in Human Plasma
Qichen Cao, Qing Zhao, Xiaohong Qian, and Wantao Ying
Part III Updated Proteome Analysis of Blood Cell Components, Vesicles, and Blood-related Fluids
11. Proteomic Analysis of Blood Extracellular Vesicles in Cardiovascular Disease by LC-MS/MS Analysis
Montserrat Baldan-Martin, Fernando de la Cuesta, Gloria Alvarez-Llamas, Gema Ruiz-Hurtado, Luis M. Ruilope, and Maria G. Barderas
12. Targeted Approach For Proteomic Analysis of a Hidden Membrane Protein
Tania Martins-Marques, Sandra I. Anjo, Teresa Ribeiro-Rodrigues, Bruno Manadas, and Henrique Girao
13. Red Blood Cells in Clinical Proteomics
Ana Sofia Carvalho, Manuel S Rodriguez, and Rune Matthiesen
14. High-throughput Quantitative Lipidomics Analysis of Non-esterified Fatty Acids in Plasma by LC-MS
Nicolas Christinat, Delphine Morin-Rivron, and Mojgan Masoodi
15. Simultaneous Enrichment of Plasma Extracellular Vesicles and Glycoproteome for Studying Disease Biomarkers
Sunil S. Adav and Siu Kwan Sze
16. Lipidomics of Human Blood Plasma by High Resolution Shotgun Mass Spectrometry
Susanne Sales, Oskar Knittelfelder, and Andrej Shevchenko
17. Proteomics Analysis of Circulating Serum Exosomes
Antonius Koller, Purvi Patel, Jenny Kim Kim, and Emily I. Chen
Part IV Antibody-based Discovery and Targeted Proteomics
18. High-density Serum/Plasma Reverse Phase Protein Arrays
Cecilia Hellstrцm, Tea Dodig-Crnkovic, Mun-Gwan Hong, Jochen M. Schwenk, Peter Nilsson, and Ronald Sjцberg
19. Antibody Colocalization Microarray for Cross-reactivity free Multiplexed Protein Analysis
Vйronique Laforte, Pik-Shan Lo, Huiyan Li, and David Juncker
20. Surface Profiling of Extracellular Vesicles From Plasma or Ascites Fluid using Dotscan Antibody Microarrays
Larissa Belov, Susannah Hallal, Kieran Matic, Jerry Zhou, Sandra Wissmueller, Nuzhat Ahmed, Sumaiya Tanjil, Stephen P. Mulligan, O. Giles Best, Richard J. Simpson, and Richard I. Christopherson
Описание: This book provides a comprehensive overview of the nitrilimine 1,3-dipole, from its initial discovery in 1959 to the most recent publications.
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