Описание: This volume presents a unique comparative treatment of the role oxidative stress plays in vertebrates and invertebrates in multiple organ systems with regards to cell death, development, aging, and human diseases, and anti-oxidant therapy.
Автор: Maurya Pawan K., Dua Kamal Название: Role of Oxidative Stress in Pathophysiology of Diseases ISBN: 9811515670 ISBN-13(EAN): 9789811515675 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Chapter 1. Preface.- Chapter 2.Introduction.- Chapter 2.1. Oxidative stress and its biological significance.- Chapter 2.2. Free radicals and biological systems.- Chapter 2.3.Oxidative stress balance system.- Chapter 3. Role of oxidative stress in aging process.- Chapter 4. Oxidative stress in diseases.- Chapter 4.1. Oxidative stress in neurology and in neurodegenerative processes.- Chapter 4.2. Oxidative stress and Cardiology.- Chapter 4.3. Oxidative stress in chronic kidney disease.- Chapter 4.4.Oxidative Stress and Atherosclerosis.- Chapter 4.5. Oxidative stress and cancer.- Chapter 4.6. Oxidative stress in respiratory diseases.- Chapter 4.7. Oxidative stress and epigenetics.- Chapter 5. Oxidative stress monitoring using in vitro and in vivo models.- Chapter 6. Detection of oxidative stress biomarkers using biosensors.- Chapter 7. Pharmaceutical treatments and strategies for anti-oxidative stress.- Chapter 8. Effects of exercise training to the oxidative stress treatment.- Chapter 9. Advancements in novel drug delivery systems: Providing a challenge and threat to oxidative stress in various diseases.- Chapter 10. Future prospects and challenges.- Chapter 11. Bibliography.- Chapter 12. Glossary.
Автор: K. Okita Название: HCV/Oxidative Stress and Liver Disease ISBN: 4431670076 ISBN-13(EAN): 9784431670070 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume containing the proceedings of the 13th Yamaguchi Symposium on Liver Disease includes discussion of the direct cellular effects of hepatitis C virus (HCV) proteins on hepatocytes and reviews evidence that oxidative stress caused primarily by the HCV core protein plays a key role in disease pathogenesis.
Автор: Sajal Chakraborti; Tapati Chakraborti; Dhrubajyoti Название: Oxidative Stress in Microbial Diseases ISBN: 9811387621 ISBN-13(EAN): 9789811387623 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This book discusses recent advances in our understanding of the role of oxidants in microbial pathophysiology, providing valuable insights into the complex role of reactive oxygen species (ROS) in host-microbial interactions. The various chapters take readers through the function of ROS in infections ranging from viral to bacterial, and describe how microorganisms have developed complex strategies to not only avoid contact with phagocyte-derived oxidants, but also protect themselves from injury when oxidants are encountered. Featuring the latest research in the field of microbial diseases, this timely book is a ready reference for scientists looking to develop new anti-microbial drugs.
Автор: Chakraborti Название: Oxidative Stress in Heart Diseases ISBN: 9811382727 ISBN-13(EAN): 9789811382727 Издательство: Springer Рейтинг: Цена: 34937.00 р. Наличие на складе: Поставка под заказ.
Описание: This book bridges the gap between fundamental and translational research in the area of heart disease. It describes a multidisciplinary approach, and demonstrates biochemical mechanisms associated with dysregulation of redox signaling, which leads heart disease. Presenting recent studies on improved forms of ROS scavenging enzymes; specific inhibitors for different ROS generating enzymes; and oxidant induced signaling pathways and their antagonists that allow subtle modulation of redox signaling, it also discusses the spatial and temporal aspects of oxidative stress in the cardiovascular system, which are of vital importance in developing better strategies for treating heart disease. Each chapter offers researchers valuable insights into identifying targets for drug development for different types of heart disease.
Автор: Chakraborti Sajal, Chakraborti Tapati, Das Salil Kumar Название: Oxidative Stress in Lung Diseases: Volume 1 ISBN: 9811384126 ISBN-13(EAN): 9789811384127 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This first volume of the comprehensive, two-volume work on oxidative stress in lung disease introduces the molecular mechanisms, and the role of oxidants in the progression of different lung diseases. The lungs of humans and animals are under constant threat from oxidants from either endogenous (e.g. in situ metabolic reactions) or exogenous sources (e.g. air pollutants). Further, oxidative stress causes the oxidation of proteins, DNA and lipids, which in turn generates secondary metabolic products. The book consists of sections, each focusing on different aspects of oxidant-mediated lung diseases. As such it is a unique reference resource for postgraduate students, biomedical researchers and also for the clinicians who are interested in studying and understanding oxidant-mediated lung diseases. The second volume will incorporate other aspects of oxidant-mediated lung diseases, including prevention and therapeutics.
Автор: Chakraborti Название: Oxidative Stress in Lung Diseases ISBN: 9813293659 ISBN-13(EAN): 9789813293656 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
A. General Aspects of reactive oxygen species-mediated lung diseases
1. "Pathology of lung diseases affected by oxidative stress"
2. "Approach of smoke-related lung damage"
3. "The state of art of NADPH Oxidase-dependent oxidative stress in lung diseases"
4. "Effects of radicals on pulmonary surfactant and role of lipid in this scenario"
5. "Infection induced oxidation and DNA repair"
6. "Oxidative stress in experimental models of acute lung injury" 7. "Oxidative Lipidomics of Lung Diseases"
B. Chronic lung diseases
8. "Oxidative stress in Lung Fibrosis"
9. "Oxidative Stress Biomarkers in COPD"
10. "Oxidative stress in emphysema"
11. "Oxidative stress induced mitochondrial dysfunction and asthma"
12. "Oxidative stress in asthma and COPD"
D. Other lung diseases
13. "Oxidative stress in environmental lung diseases"
14. "Bronchopulmonary dysplasia and oxidative stress in preterm newborns"
15. "Effect of exogeneous chemical exposure on oxidative stress induced lung diseases"
16. "Pulmonary antioxidant system in acute and chronic lung injury, pulmonary fibrosis in diabetes"
17."Mitochondrial alterations and oxidative stress in cystic fibrosis"
E. Prevention and therapeutics
18. "Flagellin/Toll-like receptor 5 response was specifically attenuated by keratin sulfate disaccharide via decreased EGFR phosphorylation in human bronchial epithelial cells"\
19. "Therapeutic targeting of oxidative stress and inflammation in COPD and asthma: Pharmacological intervention with phytochemicals"
20. "ROS: modulator of therapeutic response in non-small cell lung cancer (NSCLC)"
21. "Arsenic-induced lung injury in rats and its reversal by a garlic polysulfide"
22. "The Mitochondria-targeted Drugs for Protection of Lung Damage and Pulmonary Diseases".
23. "The use of ozone as redox modulator in the treatment of chronic pulmonary disease (COPD)"
24. "Oxidative stress and therapeutic development in lung cancer"
25.The state of art of NADPH Oxidase-dependent oxidative stress in lung diseases.
26. Pharmacological modulation of ROS impairs the airway hyper responsiveness by shifting the Th1 response in allergic inflammation induced by ovalbumin
27. Flagellin/Toll-like receptor 5 response was specifically attenuated by keratin sulfate disaccharide via decreased EGFR phosphorylation in human bronchial epithelial cells.
28. Oxidative stress in experimental models of acute lung injury.
29. Pharmacokinetics, pharmacodynamics and safety of ISO1957, a preclinical candidate possessing activity against infection.
30. Rho kinase as a therapeutic target in pulmonary vascular diseases.
31. Mesenchymal stromal cell injection protects against oxidative stress in E.coli induced lung injury in mice.
32. Phosgene induced lung damage and its amelioration by cAMP elevating compounds.
Автор: Chakraborti Sajal, Chakraborti Tapati, Das Salil Kumar Название: Oxidative Stress in Lung Diseases: Volume 1 ISBN: 9811384150 ISBN-13(EAN): 9789811384158 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This first volume of the comprehensive, two-volume work on oxidative stress in lung disease introduces the molecular mechanisms, and the role of oxidants in the progression of different lung diseases. The lungs of humans and animals are under constant threat from oxidants from either endogenous (e.g. in situ metabolic reactions) or exogenous sources (e.g. air pollutants). Further, oxidative stress causes the oxidation of proteins, DNA and lipids, which in turn generates secondary metabolic products. The book consists of sections, each focusing on different aspects of oxidant-mediated lung diseases. As such it is a unique reference resource for postgraduate students, biomedical researchers and also for the clinicians who are interested in studying and understanding oxidant-mediated lung diseases. The second volume will incorporate other aspects of oxidant-mediated lung diseases, including prevention and therapeutics.
Автор: Sajal Chakraborti; Naranjan S Dhalla; Nirmal K Gan Название: Oxidative Stress in Heart Diseases ISBN: 9811382751 ISBN-13(EAN): 9789811382758 Издательство: Springer Рейтинг: Цена: 34937.00 р. Наличие на складе: Поставка под заказ.
Описание: This book bridges the gap between fundamental and translational research in the area of heart disease. It describes a multidisciplinary approach, and demonstrates biochemical mechanisms associated with dysregulation of redox signaling, which leads heart disease. Presenting recent studies on improved forms of ROS scavenging enzymes; specific inhibitors for different ROS generating enzymes; and oxidant induced signaling pathways and their antagonists that allow subtle modulation of redox signaling, it also discusses the spatial and temporal aspects of oxidative stress in the cardiovascular system, which are of vital importance in developing better strategies for treating heart disease. Each chapter offers researchers valuable insights into identifying targets for drug development for different types of heart disease.
Описание: This book represents current findings on the impact of oxidative stress in the pathogenesis of diseases and underlying mechanisms of antioxidants influencing health and disease processes. The book is divided into seven sections that describe how antioxidants defend oxidative stress-mediated diseases as well as recent developments, future opportunities, and challenges. Sections 1 analyses the role of oxidative stress in aging and associated diseases as well as the use of antioxidants in health maintenance, preventing and repairing injuries caused by oxidative stress. Section 2 represents the status of various antioxidants in cigarette smoking and antioxidant defense against exercise-induced oxidative stress. Section 3 focuses on the effect of oxidative stress in the pathogenesis of neurodegeneration and the existing status of antioxidant therapy. Section 4 covers the impact of oxidative stress at different levels of chronic degenerative diseases, as well as treatment with antioxidants to revert and diminish the cellular injury. Section 5 offers the importance of antioxidants in abating the pathological processes involved in hypertension and stroke. Section 6 presents the complexity associated with oxidative stress and metabolic disorders as well as the potential of antioxidants used in amelioration of related pathologies. Section 7 discusses the antioxidant defense against oxidative stress-mediated erectile dysfunctions and the significance of antioxidants in pregnancy. The book represents the copious set of specific research updates and diaphanous understanding of oxidative stress-mediated cellular damages and role of antioxidants in disease processes from experienced and eminent academicians, researchers, and scientists from throughout the world. Suitable for professionals, academicians, students, researchers, scientists and industrialists around the world in the biomedical, health, and life science fields.
Автор: Natan Gadoth; Hans Hilmar G?bel Название: Oxidative Stress and Free Radical Damage in Neurology ISBN: 1617797162 ISBN-13(EAN): 9781617797163 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book focuses on clinical and research issues regarding the interplay of free radicals and the human nervous system. Its comprehensive coverage extends to numerous antioxidants and their possible therapeutic role in neurological disorders.
Автор: Mohinder Bansal; Naveen Kaushal Название: Oxidative Stress Mechanisms and their Modulation ISBN: 8132220315 ISBN-13(EAN): 9788132220312 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Research over the years has demonstrated that free radicals mediated oxidative stress lies at the helm of almost all patho-physiological phenomena. These findings emphasize on the need to understand the underlying molecular mechanism(s) and their critical role in the pathogenesis. This book aims to focus on these areas to provide readers a comprehensive outlook about the major redox sensitive pathways and networks involved in various disease conditions. In the first chapter of the book, basic information about the oxidative stress, its generation, its biomarkers and its role in body are discussed. In the next three chapters, the role of oxidative stress in various pathologies ranging from neurological disorders, to cardiovascular diseases, cancers, metabolic diseases and ageing have been described. Chapter 5 cumulatively describes the most important molecular signaling pathways that are affected by reactive oxygen species (ROS). These are the mechanisms which are common denominators in various pathological states. In the next part of the book, various antioxidant strategies to target and mitigate ROS have been discussed with details on the mechanisms. Selenium, being the research focus and interest of the authors for years, the role of selenium as an antioxidant as part of selenoproteins has been included in the book. Finally, the book culminates with authors’ perspective on the future of the redox biology field. Throughout the book, efforts have been made to use simplified language and suitable figures for ease to understand the contents. Although the authors have tried to touch on all the different aspects of oxidative stress in detail, the fact that it is a continuously growing field with updates coming every day, there might be some areas which might not be described in depth. This book is designed for students, young scientists to get acquainted with the redox biology. Overall, this book is a reference to understand the redox regulation of cellular signaling pathways involved in pathogenesis.
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