Описание: This volume presents a unique comparative treatment of the role oxidative stress plays in vertebrates and invertebrates in multiple organ systems with regards to cell death, development, aging, and human diseases, and anti-oxidant therapy.
Автор: Chakraborti Sajal, Chakraborti Tapati, Das Salil Kumar Название: Oxidative Stress in Lung Diseases: Volume 1 ISBN: 9811384150 ISBN-13(EAN): 9789811384158 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This first volume of the comprehensive, two-volume work on oxidative stress in lung disease introduces the molecular mechanisms, and the role of oxidants in the progression of different lung diseases. The lungs of humans and animals are under constant threat from oxidants from either endogenous (e.g. in situ metabolic reactions) or exogenous sources (e.g. air pollutants). Further, oxidative stress causes the oxidation of proteins, DNA and lipids, which in turn generates secondary metabolic products. The book consists of sections, each focusing on different aspects of oxidant-mediated lung diseases. As such it is a unique reference resource for postgraduate students, biomedical researchers and also for the clinicians who are interested in studying and understanding oxidant-mediated lung diseases. The second volume will incorporate other aspects of oxidant-mediated lung diseases, including prevention and therapeutics.
Автор: Chakraborti Название: Oxidative Stress in Heart Diseases ISBN: 9811382727 ISBN-13(EAN): 9789811382727 Издательство: Springer Рейтинг: Цена: 34937.00 р. Наличие на складе: Поставка под заказ.
Описание: This book bridges the gap between fundamental and translational research in the area of heart disease. It describes a multidisciplinary approach, and demonstrates biochemical mechanisms associated with dysregulation of redox signaling, which leads heart disease. Presenting recent studies on improved forms of ROS scavenging enzymes; specific inhibitors for different ROS generating enzymes; and oxidant induced signaling pathways and their antagonists that allow subtle modulation of redox signaling, it also discusses the spatial and temporal aspects of oxidative stress in the cardiovascular system, which are of vital importance in developing better strategies for treating heart disease. Each chapter offers researchers valuable insights into identifying targets for drug development for different types of heart disease.
Автор: Chakraborti Sajal, Chakraborti Tapati, Chattopadhyay Dhrubajyoti Название: Oxidative Stress in Microbial Diseases ISBN: 9811387656 ISBN-13(EAN): 9789811387654 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book discusses recent advances in our understanding of the role of oxidants in microbial pathophysiology, providing valuable insights into the complex role of reactive oxygen species (ROS) in host-microbial interactions. The various chapters take readers through the function of ROS in infections ranging from viral to bacterial, and describe how microorganisms have developed complex strategies to not only avoid contact with phagocyte-derived oxidants, but also protect themselves from injury when oxidants are encountered. Featuring the latest research in the field of microbial diseases, this timely book is a ready reference for scientists looking to develop new anti-microbial drugs.
Автор: Chakraborti Sajal, Chakraborti Tapati, Das Salil Kumar Название: Oxidative Stress in Lung Diseases: Volume 1 ISBN: 9811384126 ISBN-13(EAN): 9789811384127 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This first volume of the comprehensive, two-volume work on oxidative stress in lung disease introduces the molecular mechanisms, and the role of oxidants in the progression of different lung diseases. The lungs of humans and animals are under constant threat from oxidants from either endogenous (e.g. in situ metabolic reactions) or exogenous sources (e.g. air pollutants). Further, oxidative stress causes the oxidation of proteins, DNA and lipids, which in turn generates secondary metabolic products. The book consists of sections, each focusing on different aspects of oxidant-mediated lung diseases. As such it is a unique reference resource for postgraduate students, biomedical researchers and also for the clinicians who are interested in studying and understanding oxidant-mediated lung diseases. The second volume will incorporate other aspects of oxidant-mediated lung diseases, including prevention and therapeutics.
Автор: Sajal Chakraborti; Tapati Chakraborti; Dhrubajyoti Название: Oxidative Stress in Microbial Diseases ISBN: 9811387621 ISBN-13(EAN): 9789811387623 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This book discusses recent advances in our understanding of the role of oxidants in microbial pathophysiology, providing valuable insights into the complex role of reactive oxygen species (ROS) in host-microbial interactions. The various chapters take readers through the function of ROS in infections ranging from viral to bacterial, and describe how microorganisms have developed complex strategies to not only avoid contact with phagocyte-derived oxidants, but also protect themselves from injury when oxidants are encountered. Featuring the latest research in the field of microbial diseases, this timely book is a ready reference for scientists looking to develop new anti-microbial drugs.
Автор: Maurya Pawan K., Dua Kamal Название: Role of Oxidative Stress in Pathophysiology of Diseases ISBN: 9811515670 ISBN-13(EAN): 9789811515675 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Chapter 1. Preface.- Chapter 2.Introduction.- Chapter 2.1. Oxidative stress and its biological significance.- Chapter 2.2. Free radicals and biological systems.- Chapter 2.3.Oxidative stress balance system.- Chapter 3. Role of oxidative stress in aging process.- Chapter 4. Oxidative stress in diseases.- Chapter 4.1. Oxidative stress in neurology and in neurodegenerative processes.- Chapter 4.2. Oxidative stress and Cardiology.- Chapter 4.3. Oxidative stress in chronic kidney disease.- Chapter 4.4.Oxidative Stress and Atherosclerosis.- Chapter 4.5. Oxidative stress and cancer.- Chapter 4.6. Oxidative stress in respiratory diseases.- Chapter 4.7. Oxidative stress and epigenetics.- Chapter 5. Oxidative stress monitoring using in vitro and in vivo models.- Chapter 6. Detection of oxidative stress biomarkers using biosensors.- Chapter 7. Pharmaceutical treatments and strategies for anti-oxidative stress.- Chapter 8. Effects of exercise training to the oxidative stress treatment.- Chapter 9. Advancements in novel drug delivery systems: Providing a challenge and threat to oxidative stress in various diseases.- Chapter 10. Future prospects and challenges.- Chapter 11. Bibliography.- Chapter 12. Glossary.
Автор: Chakraborti Название: Oxidative Stress in Lung Diseases ISBN: 9813293659 ISBN-13(EAN): 9789813293656 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
A. General Aspects of reactive oxygen species-mediated lung diseases
1. "Pathology of lung diseases affected by oxidative stress"
2. "Approach of smoke-related lung damage"
3. "The state of art of NADPH Oxidase-dependent oxidative stress in lung diseases"
4. "Effects of radicals on pulmonary surfactant and role of lipid in this scenario"
5. "Infection induced oxidation and DNA repair"
6. "Oxidative stress in experimental models of acute lung injury" 7. "Oxidative Lipidomics of Lung Diseases"
B. Chronic lung diseases
8. "Oxidative stress in Lung Fibrosis"
9. "Oxidative Stress Biomarkers in COPD"
10. "Oxidative stress in emphysema"
11. "Oxidative stress induced mitochondrial dysfunction and asthma"
12. "Oxidative stress in asthma and COPD"
D. Other lung diseases
13. "Oxidative stress in environmental lung diseases"
14. "Bronchopulmonary dysplasia and oxidative stress in preterm newborns"
15. "Effect of exogeneous chemical exposure on oxidative stress induced lung diseases"
16. "Pulmonary antioxidant system in acute and chronic lung injury, pulmonary fibrosis in diabetes"
17."Mitochondrial alterations and oxidative stress in cystic fibrosis"
E. Prevention and therapeutics
18. "Flagellin/Toll-like receptor 5 response was specifically attenuated by keratin sulfate disaccharide via decreased EGFR phosphorylation in human bronchial epithelial cells"\
19. "Therapeutic targeting of oxidative stress and inflammation in COPD and asthma: Pharmacological intervention with phytochemicals"
20. "ROS: modulator of therapeutic response in non-small cell lung cancer (NSCLC)"
21. "Arsenic-induced lung injury in rats and its reversal by a garlic polysulfide"
22. "The Mitochondria-targeted Drugs for Protection of Lung Damage and Pulmonary Diseases".
23. "The use of ozone as redox modulator in the treatment of chronic pulmonary disease (COPD)"
24. "Oxidative stress and therapeutic development in lung cancer"
25.The state of art of NADPH Oxidase-dependent oxidative stress in lung diseases.
26. Pharmacological modulation of ROS impairs the airway hyper responsiveness by shifting the Th1 response in allergic inflammation induced by ovalbumin
27. Flagellin/Toll-like receptor 5 response was specifically attenuated by keratin sulfate disaccharide via decreased EGFR phosphorylation in human bronchial epithelial cells.
28. Oxidative stress in experimental models of acute lung injury.
29. Pharmacokinetics, pharmacodynamics and safety of ISO1957, a preclinical candidate possessing activity against infection.
30. Rho kinase as a therapeutic target in pulmonary vascular diseases.
31. Mesenchymal stromal cell injection protects against oxidative stress in E.coli induced lung injury in mice.
32. Phosgene induced lung damage and its amelioration by cAMP elevating compounds.
Автор: Chakraborti Sajal, Dhalla Naranjan S., Dikshit Madhu Название: Modulation of Oxidative Stress in Heart Disease ISBN: 9811389454 ISBN-13(EAN): 9789811389450 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book highlights the multifaceted roles of Reactive Oxygen Species (ROS) in modulating normal cellular and molecular mechanisms during the development of different types of heart disease. Each chapter in the book deals with the role that altered redox homeostasis plays in the pathophysiology of heart disease. In addition, the book explains how reactive oxidant species interact with their targets and provides novel strategies for attenuating oxidative stress-induced types of heart disease. The book not only covers ROS-induced response in heart disease at the cellular level, but also demonstrates that an imbalance of redox states has its roots in our genes, and explains the ways gene expression is regulated. In turn, it reviews potential sources of ROS, their pathological effects on the heart, and potential sites for therapeutic interventions.
Автор: Mieczyslaw Pokorski Название: Oxidative Stress and Cardiorespiratory Function ISBN: 3319097210 ISBN-13(EAN): 9783319097213 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Cardiorespiratory function is prominently affected by oxidative stress. Cigarette smoking is the archetype of oxidative and nitrative stress and free radical formation. New adverse effects of smoking keep on propping up in research. The chapters provide the comprehensive view of new developments in this area regarding cardiovascular and lung function and muscle catabolism. Alterations in inflammatory cytokines and proteins as well as degradation of muscle proteins due to smoking, by far unrecognized, caused by oxidative stress also are presented. Much less is known about the effect of cognitive stress on vagally-mediated cardiorespiratory function and surprisingly, on vagal immune pathway. The experimental studies also show that clinically important meconium aspiration syndrome contains an oxidative trait which is amenable to antioxidative treatment. This volume creates a source of information on the damaging role of oxidative stress in cardiorespiratory function that has by far not been available.
Название: Vitamin D Oxidative Stress, Immunit ISBN: 1138199443 ISBN-13(EAN): 9781138199446 Издательство: Taylor&Francis Рейтинг: Цена: 10411.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Vitamin D insufficiency/deficiency is a worldwide, public health problem in both developed and developing countries. Rickets among infants has reemerged. Low levels of vitamin D are associated with increased risk and mortality from cancer. At the same time, the beneficial effects of vitamin D on a host of conditions have recently been discovered. Focusing on areas not extensively covered in other comparable books, Vitamin D: Oxidative Stress, Immunity, and Aging highlights the most recent research findings on the impact of this nutrient in oxidative stress, immunity, and aging.
A state-of-the-art compilation of essential information, this book explores:
Vitamin D and its genomic and nongenomic effects, the role of therapeutic analogs in treating disease, and the production of vitamin D by the body
The role vitamin D plays in modulating oxidative stress--with emphasis on cancer, stress-mediated diseases, photo-protection of the skin, and energy metabolism
Beneficial effects of vitamin D in regulating the immune response and its importance in protecting against autoimmune, infectious, and inflammatory diseases
The role vitamin D plays in the regulation of the aging process--including aspects of oxidative stress, senescence, and mortality, as well as its role in protection against cardiovascular disease and nervous system disorders
This book represents an important contribution toward understanding the mechanisms by which vitamin D promotes health, increasing awareness of the importance that vitamin D plays during development, at birth, and throughout the aging process. It is a valuable reference for researchers in academia, nutrition, medicine, and industry.
Автор: R.C. Cutler; L. Packer; J. Bertram; A. Mori Название: Oxidative Stress and Aging ISBN: 3034873395 ISBN-13(EAN): 9783034873390 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Oxidative stress and aging Over the past several years there has been an extraordinarily rapid growth in our knowledge of free radical chemistry and its possible involvement in both normal essential biology and age- related disease and dysfunction. Much of this growth in the traditionally separate sciences of chemistry and molecular gerontology occurred independently, with little interaction or communi- cation between the scientists working in these two fields. In view of the growing maturity of the two fields and the potential importance of advancing our knowledge in the area of oxidative stress and aging, we perceived a critical need to organize an international conference the "First Inter- national Conference on Oxidative Stress and Aging" in Hawaii in 1994 to bring together the world's leading scientists in the fields of reactive oxygen species and molecular gerontology. The objective of this conference was to provide a unique opportunity for scholars working in these two related and rapidly growing fields to participate in the exchange, integration, and synthesis of new concepts and ideas, to engage in constructive criticism and to initiate new collaborative research projects. The conference focused on the molecular and cellular aspects of aging as related to oxidative stress. It was one of the largest and most comprehensive international conferences held in molecular gerontology. At this conference a call was made for submission of papers to be used in the publication of a book covering the major contributions of the meeting.
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