Описание: In The Alchemy of Disease, John Whysner offers an accessible and compelling history of toxicology and its key findings. He details the experiments and discoveries that revealed the causal connections between chemical exposures and diseases.
Автор: K. Aktories; I. Just Название: Bacterial Protein Toxins ISBN: 3642085407 ISBN-13(EAN): 9783642085406 Издательство: Springer Рейтинг: Цена: 78365.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With contributions by numerous experts
Автор: Gian Paolo Rossini Название: Toxins and biologically active compounds from microalgae ISBN: 1482231468 ISBN-13(EAN): 9781482231465 Издательство: Taylor&Francis Рейтинг: Цена: 29093.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Toxins and Biologically Active Compounds from Microalgae: Volume 2: Biological Effects and Risk Management is devoted to the effects toxic microalgae and their poisonous products exert on living systems and how they may affect human activities. The most advanced information regarding the molecular mechanisms of action of major groups of toxins is presented, to frame for the description of toxic responses found in living systems exposed to microalgal toxins. Accounts of the recognized environmental effects of harmful algal blooms and the existing therapeutic applications of some toxins have been included.
The picture is completed by the description of current initiatives to manage the risks posed by toxic microalgae, including strategies for the detoxification of contaminated seafood and the efforts to use most advanced informatic tools for the development of models for robust predictions regarding the appearance and the dynamics of harmful algal blooms. The complexity of risk management in the field is presented from a global perspective by highlighting major issues approached in world regions whose economic importance with regard to the production and commercialization of seafood is undeniable.
Автор: Salem Harry, Katz Sidney A., Marrs Tim Название: Aerobiology: The Toxicology of Airborne Pathogens and Toxins ISBN: 1849735948 ISBN-13(EAN): 9781849735940 Издательство: Royal Society of Chemistry Рейтинг: Цена: 37805.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book focusses on the toxicological aspects of aerobiology, considering the adverse health effects associated with the inhalation of airborne biological particulates.
This book discusses the decoding of the lytic mechanism of an ?-helical pore-forming toxin, YaxAB, composed of two different subunits. Pore-forming toxins (PFTs) are among the most common bacterial toxins. They are produced by a variety of pathogens, which infect a wide range of organisms including plants, insects and humans. Yet the maturation of these particles and the structural changes required for pore formation are still poorly understood for many PFT families.
Using a diverse panel of biochemical and structural techniques, including X-ray crystallography and cryo-electron microscopy, Dr. Br?uning and colleagues have succeeded in identifying the mechanistic contributions of the two toxin components and elucidating the lytic state of the pore complex. The results of this thesis on the YaxAB system are applicable to orthologues from agriculturally relevant insect pathogens, and offer valuable structural and mechanistic insights to inform future bioengineering efforts.
Автор: Hassan Areej Название: Everyday Environmental Toxins: Children S Exposure Risks ISBN: 1771881011 ISBN-13(EAN): 9781771881012 Издательство: Taylor&Francis Рейтинг: Цена: 18374.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This title includes a number of Open Access chapters.
This collection of timely chapters presents a nuanced study of environmental toxins and the risks they pose to children's development. The book details the impact of a number of commonplace environmental toxins, focusing on everyday exposure to tobacco smoke, lead, pesticides, and flame retardants. There is growing recognition that the impact of the environment on children's health is of critical importance for both current and future generations. In the last half-century, thousands of chemicals have been introduced into the environment with limited--although growing--research on the consequences of exposure. It has been proven that children and adolescents are far more vulnerable than adults to these environmental toxins by virtue of children's behaviors, higher metabolic rate, greater skin area relative to their volume, and still developing organ systems. Increased number of ear infections, poor asthma control, and learning disabilities are just some of the adverse outcomes that have been noted.
This well-researched book:
- Presents detailed information on why children are more vulnerable to everyday toxins
- Discusses why new approaches to medical care are necessary that take into account children's unique physiology and development
- Offers well-defined research on tobacco smoking on prenatal development as well as children's exposure to tobacco smoke during their early years, particularly the evidence of asthma and asthma-like symptoms
- Examines the possible health effects of children born to mothers living in areas of natural gas development
- Looks at the health effects of childhood exposure to environmental lead, using GIS technology to study areas of potentially high lead concentrations
- Discusses the possible effects of agricultural pesticides on children's health during gestation
- Presents studies on prenatal and adolescent exposure to PBDEs used as flame retardants in many household and commercial products to prevent fire
This valuable book, edited by a pediatric clinician at Boston's Children's Hospital, provides a wealth of information on this important issue. The book concludes with an article by the World Health Organization, which offers a practical and comprehensive summary of a series of action steps. The book aims to create greater awareness to spur additional research, provide vital information to clinicians, and send a powerful message to government officials, putting pressure on them to develop policies that improve the quality of the environment and spare children the detrimental effects of such exposures.
Автор: Moss, Название: Handbook of Natural Toxins, Volume 8 ISBN: 0367401835 ISBN-13(EAN): 9780367401832 Издательство: Taylor&Francis Рейтинг: Цена: 9798.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume describes the structure and function of bacterial toxins and presents a comprehensive review of virulence factors, providing recent information concerning cell physiology and biochemistry, as well as new toxin tools for experimental studies and clinical therapy. A wide variety of toxic proteins, including the toxins that cause diptheria, cholera, pertussis, shigellosis, tetanus, botulism and anthrax, are discussed.;The work is aimed at microbiologists, biochemists, endocrinologists, toxicologists, infectious disease specialists, pathologists, public health officials, and upper-level undergraduate and graduate students in these disciplines.
Описание: Poisonous mushrooms have fascinated scientists and laypersons alike for thousands of years. Almost all mushroom fatalities are due to the genus Amanita, whose poetic common names (death cap, destroying angel) attest to their lethality. In his classic 1986 book, Theodor Wieland covered the state of our knowledge about the chemistry and biochemistry of the toxins of Amanita mushrooms up until that time, with a particular focus on the decades of chemical research by him and the Wieland dynasty (including his father, brother, brother-in-law, and cousin). Wieland’s book is now mainly of historical interest, with its exhaustive overview of the early chemical studies done without benefit of methods taken for granted by modern chemists.
This book is a complete top-to-bottom revision of Wieland’s 1986 book. The material covers history, chemistry, and biology with equal thoroughness. It should be of interest to natural products chemists and biologists, professional and amateur mycologists, and toxicologists.
The three scientific fields that are most relevant to the book are natural products chemistry, mycology, and fungal molecular genetics. Dr. Walton is an expert in all three. To maximize the broad utility and appeal of the book, care has been taken to define all technical terms specific to a particular discipline, so that, for example, mycologists will be able to understand the relevant chemistry, and chemists will be able to understand the relevant fungal biology.
Автор: K. Aktories; I. Just Название: Bacterial Protein Toxins ISBN: 3540661255 ISBN-13(EAN): 9783540661252 Издательство: Springer Рейтинг: Цена: 78366.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With contributions by numerous experts
Автор: V.R. Jr. Dowell; A.E. Pohland; J.L. Richard Название: Microbial Toxins in Foods and Feeds ISBN: 146127916X ISBN-13(EAN): 9781461279167 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Although toxigenic fungi have been known since ancient times, modern mycotoxinology probably began with the early work of Joseph Forgacs and his colleagues in the 1950s. This science grew tremendously with the discovery of aflatoxins and aflatoxicoses in the early 1960s, particulorly following the finding of the carcinogenicity of aflatoxins in test animol species. The discovery and identification of new mycotoxins and mycotoxi- coses, development of analytical procedures, attempted measurement of human and animal exposure, evaluation of toxicological effects, estimotiol' of risk due to human exposure, and development of regulatory control programs have been the major research goals over the past 30 years. In recent years there has also been an explosive growth in our knowledge of the metabolites produced by the algae, especially the dinoflagellate-produced toxins, and the transmission of such toxins up, e food chain to reef fish and shellfish. This knowledge has been invalualdl' in understanding and controlling human illness resulting from ingestion of seafood. We are now, for the first time, able to deal with such common seafood-related human diseases as paralytic, neurotoxic and amnesic shellfish and ciguatera poisoning.
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