The Mechanobiology and Mechanophysiology of Military-Related Injuries, Gefen Amit, Epstein Yoram

Автор: Amit Gefen; Dafna Benayahu
Название: The Mechanobiology of Obesity and Related Diseases
ISBN: 3319376268 ISBN-13(EAN): 9783319376264
Издательство: Springer
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Цена: 14365.00 р.
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Описание: Mechanical behavior and properties of adipose tissue.- Mathematical models of adipose tissue dynamics.- Mechanical stretching and signaling pathways in adipogenesis- Role of mechanical stimulations in directing mesenchymal stem cell adipogenesis.- The vicious cycle of estrogen consumption and obesity: The role of mechanotransduction.- Extracellular matrix remodeling and mechanical stresses as modulators of adipose tissue metabolism and inflammation.- The Impact of Obesity and Weight Loss on Gait in Adults.- Excessive Weight Bearing Compromises Foot Structure and Function across the Lifespan.- Obesity, Osteoarthritis and Aging: The Biomechanical Links.- Impaired neutrophil mechanoregulation by fluid flow: A potential contributing factor for microvascular dysfunction in obesity.- Mechanotransduction and the myogenic response in diabetes.- Role of adipose cells in tumor microenvironment.

Автор: Amit Gefen; Dafna Benayahu
Название: The Mechanobiology of Obesity and Related Diseases
ISBN: 3319093355 ISBN-13(EAN): 9783319093352
Издательство: Springer
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Цена: 19591.00 р.
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Описание: Mechanical behavior and properties of adipose tissue.- Mathematical models of adipose tissue dynamics.- Mechanical stretching and signaling pathways in adipogenesis- Role of mechanical stimulations in directing mesenchymal stem cell adipogenesis.- The vicious cycle of estrogen consumption and obesity: The role of mechanotransduction.- Extracellular matrix remodeling and mechanical stresses as modulators of adipose tissue metabolism and inflammation.- The Impact of Obesity and Weight Loss on Gait in Adults.- Excessive Weight Bearing Compromises Foot Structure and Function across the Lifespan.- Obesity, Osteoarthritis and Aging: The Biomechanical Links.- Impaired neutrophil mechanoregulation by fluid flow: A potential contributing factor for microvascular dysfunction in obesity.- Mechanotransduction and the myogenic response in diabetes.- Role of adipose cells in tumor microenvironment.

Автор: Yanhang Zhang
Название: Multi-scale Extracellular Matrix Mechanics and Mechanobiology
ISBN: 3030201813 ISBN-13(EAN): 9783030201814
Издательство: Springer
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Цена: 13974.00 р.
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Описание: This book describes the current state of knowledge in the field of multi-scale ECM mechanics and mechanobiology with a focus on experimental and modelling studies in biomechanical characterization, advanced optical microscopy and imaging, as well as computational modeling. This book also discusses the scale dependency of ECM mechanics, translation of mechanical forces from tissue to cellular level, and advances and challenges in improving our understanding of cellular mechanotransduction in the context of living tissues and organisms.

Автор: Chien
Название: Molecular and Cellular Mechanobiology
ISBN: 1493956159 ISBN-13(EAN): 9781493956159
Издательство: Springer
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Цена: 21661.00 р.
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Описание: This book will cover the cutting-edge developments in molecular and cellular mechanobiology to date. Readers will have a clear understanding of mechanobiology at the molecular and cellular levels, encompassing the mechanosensors, transducers, and transcription. An integrative approach across different scales from molecular sensing to mechanotransduction and gene modulation for physiological regulation of cellular functions will be explored, as well as applications to pathophysiological states in disease. A comprehensive understanding of the roles of physicochemical microenvironment and intracellular responses in determining cellular function in health and disease will also be discussed.

Автор: Chien Shu, Engler Adam J., Wang Peter Yingxiao
Название: Molecular and Cellular Mechanobiology
ISBN: 1493981668 ISBN-13(EAN): 9781493981663
Издательство: Springer
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Цена: 23757.00 р.
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Описание: This book will cover the cutting-edge developments in molecular and cellular mechanobiology to date. Readers will have a clear understanding of mechanobiology at the molecular and cellular levels, encompassing the mechanosensors, transducers, and transcription. An integrative approach across different scales from molecular sensing to mechanotransduction and gene modulation for physiological regulation of cellular functions will be explored, as well as applications to pathophysiological states in disease. A comprehensive understanding of the roles of physicochemical microenvironment and intracellular responses in determining cellular function in health and disease will also be discussed.

Автор: Gerhard A. Holzapfel; Raymond W. Ogden
Название: Multiscale Soft Tissue Mechanics and Mechanobiology
ISBN: 9402415122 ISBN-13(EAN): 9789402415124
Издательство: Springer
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Цена: 20962.00 р.
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Описание: This volume covers aspects of multiscale modeling of the mechanics and mechanobiology of soft biological tissues. The individual contributions focus on the constitutive modeling from the micro to the macro level in addition to computational modeling and simulation. It consists of peer-reviewed papers written by leading international authorities and will serve as a major state-of-the-art source of reference for the next few years. It includes both review articles and original articles. Previously published in the Journal of Elasticity, Volume 129, Issue 1-2, December 2017.

Автор: Damien Lacroix; Marzia Brunelli; C?cile Perrault;
Название: Multiscale Mechanobiology in Tissue Engineering
ISBN: 9811340560 ISBN-13(EAN): 9789811340567
Издательство: Springer
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Цена: 13974.00 р.
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Описание: This book focuses on the mechanobiological principles in tissue engineering with a particular emphasis on the multiscale aspects of the translation of mechanical forces from bioreactors down to the cellular level. The book contributes to a better understanding of the design and use of bioreactors for tissue engineering and the use of mechanical loading to optimize in vitro cell culture conditions. It covers experimental and computational approaches and the combination of both to show the benefits that computational modelling can bring to experimentalists when studying in vitro cell culture within a scaffold. With topics from multidisciplinary fields of the life sciences, medicine, and engineering, this work provides a novel approach to the use of engineering tools for the optimization of biological processes and its application to regenerative medicine. The volume is a valuable resource for researchers and graduate students studying mechanobiology and tissue engineering. For undergraduate students it also provides deep insight into tissue engineering and its use in the design of bioreactors. The book is supplemented with extensive references for all chapters to help the reader to progress through the study of each topic.

Автор: Larry A. Taber
Название: Continuum Modeling in Mechanobiology
ISBN: 3030432076 ISBN-13(EAN): 9783030432072
Издательство: Springer
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Цена: 15372.00 р.
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Описание: This book examines key theoretical tools that are currently used to develop mathematical models as an aid in understanding the biological response of cells and tissues to mechanical stimuli. This is an ideal book for biomechanical engineers who work on problems in mechanobiology and tissue engineering.

Автор: Peter Pivonka
Название: Multiscale Mechanobiology of Bone Remodeling and Adaptation
ISBN: 3319864890 ISBN-13(EAN): 9783319864891
Издательство: Springer
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Цена: 16070.00 р.
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Описание: The book presents state-of-the-art developments in multiscale modeling and latest experimental data on multiscale mechanobiology of bone remodeling and adaptation including fracture healing applications. The multiscale models include musculoskeletal models describing bone-muscle interactions during daily activities such as walking or running, micromechanical models for estimation of bone mechanical properties, bone remodeling and adaptation models, cellular models describing the complex bone-cell interactions taking into account biochemical and biomechanical regulatory factors.Also subcellular processes are covered including arrangement of actin filaments due to mechanical loading and change of receptor configurations.

Автор: Peter Pivonka
Название: Multiscale Mechanobiology of Bone Remodeling and Adaptation
ISBN: 3319588435 ISBN-13(EAN): 9783319588438
Издательство: Springer
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Цена: 22359.00 р.
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Описание: The book presents state-of-the-art developments in multiscale modeling and latest experimental data on multiscale mechanobiology of bone remodeling and adaptation including fracture healing applications. The multiscale models include musculoskeletal models describing bone-muscle interactions during daily activities such as walking or running, micromechanical models for estimation of bone mechanical properties, bone remodeling and adaptation models, cellular models describing the complex bone-cell interactions taking into account biochemical and biomechanical regulatory factors.Also subcellular processes are covered including arrangement of actin filaments due to mechanical loading and change of receptor configurations.

Автор: Tim McGloughlin
Название: Biomechanics and Mechanobiology of Aneurysms
ISBN: 3642270751 ISBN-13(EAN): 9783642270758
Издательство: Springer
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Цена: 19589.00 р.
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Описание: This book offers new insights into aneurysm aetiology and behavior based on the most recent biomechanics research related to this important topic. It details key factors influencing aneurysm behavior and treatment.

Название: Mechanobiology Handbook
ISBN: 1138072265 ISBN-13(EAN): 9781138072268
Издательство: Taylor&Francis
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Цена: 16078.00 р.
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Описание:

Mechanobiology--the study of the effects of mechanical environments on the biological processes of cells--has evolved from traditional biomechanics via the incorporation of strong elements of molecular and cell biology. Currently, a broad range of organ systems are being studied by surgeons, physicians, basic scientists, and engineers. These mechanobiologists aim to create new therapies and further biological understanding by quantifying the mechanical environment of cells and the molecular mechanisms of mechanically induced pathological conditions.

To achieve these goals, investigators must be familiar with both the basic concepts of mechanics and the modern tools of cellular/molecular biology. Unfortunately, current literature contains numerous studies that misuse standard mechanical estimations and terminology, or fail to implement appropriate molecular analyses. Therefore, the Mechanobiology Handbook not only presents cutting-edge research findings across various fields and organ systems, but also provides the elementary chapters on mechanics and molecular analysis techniques to encourage cross-field understanding and appropriate planning.

Aided by the continuous advancement of research tools in both mechanics and biology, more sophisticated experiments and analyses are possible--thus fueling the growth of the field of mechanobiology. Considering the complexity of the mechanics and the biology of the human body, most of the world of biomechanics remains to be studied. Since the field is still developing, the Mechanobiology Handbook does not force one unified theory, but brings out many different viewpoints and approaches to stimulate further research questions.