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Computational Design of Ligand Binding Proteins, Stoddard Barry L.


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Автор: Stoddard Barry L.
Название:  Computational Design of Ligand Binding Proteins
ISBN: 9781493980802
Издательство: Springer
Классификация:

ISBN-10: 1493980807
Обложка/Формат: Paperback
Страницы: 375
Вес: 0.68 кг.
Дата издания: 21.04.2018
Серия: Methods in molecular biology
Язык: English
Издание: Softcover reprint of
Иллюстрации: 77 tables, color; 13 tables, black and white; 76 illustrations, color; 18 illustrations, black and white; xvi, 375 p. 94 illus., 76 illus. in color.
Размер: 25.40 x 17.78 x 2.06 cm
Читательская аудитория: General (us: trade)
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This volume provides a collection of protocols and approaches for the creation of novel ligand binding proteins, compiled and described by many of todays leaders in the field of protein engineering. Chapters focus on modeling protein ligand binding sites, accurate modeling of protein-ligand conformational sampling, scoring of individual docked solutions, structure-based design program such as ROSETTA, protein engineering, and additional methodological approaches. Examples of applications include the design of metal-binding proteins and light-induced ligand binding proteins, the creation of binding proteins that also display catalytic activity, and the binding of larger peptide, protein, DNA and RNA ligands. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Дополнительное описание: In silico Identification and Characterization of Protein-Ligand Binding Sites.- Computational Modeling of Small Molecule Ligand Binding Interactions and Affinities.- Binding Site Prediction of Proteins with Organic Compounds or Peptides Using GALAXY Web S



Computational Design of Ligand Binding Proteins

Автор: Barry L. Stoddard
Название: Computational Design of Ligand Binding Proteins
ISBN: 1493935674 ISBN-13(EAN): 9781493935673
Издательство: Springer
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Цена: 20962.00 р.
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Описание: This volume provides acollection of protocols and approaches for the creation of novel ligand bindingproteins, compiled and described by many of today`s leaders in the field ofprotein engineering.

Identification of Ligand Binding Site and Protein-Protein Interaction Area

Автор: Irena Roterman-Konieczna
Название: Identification of Ligand Binding Site and Protein-Protein Interaction Area
ISBN: 9401782849 ISBN-13(EAN): 9789401782845
Издательство: Springer
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Цена: 22201.00 р.
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Описание: This volume presents a review of the latest numerical techniques used to identify ligand binding and protein complexation sites. It offers a comparative analysis of models based on geometry versus those based on knowledge of the biological phenomenon.

Protein-Ligand Interactions

Автор: Mark A. Williams; Tina Daviter
Название: Protein-Ligand Interactions
ISBN: 1627033971 ISBN-13(EAN): 9781627033978
Издательство: Springer
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Цена: 23058.00 р.
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Описание: In its revised 2nd Edition, this Methods in Molecular Biology (TM) book provides a complete introduction to common and emerging procedures for characterizing the interactions of individual proteins. Offers materials lists, reproducible protocols, notes and more.

Integrin-Ligand Interaction

Автор: Johannes A. Elbe
Название: Integrin-Ligand Interaction
ISBN: 1475740662 ISBN-13(EAN): 9781475740660
Издательство: Springer
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Цена: 15672.00 р.
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Описание: When James Meredith enrolled as the first African American student at the University of Mississippi in 1962, the resulting riots produced more casualties than any other clash of the civil rights era. Eagles shows that the violence resulted from the university`s and the state`s long defiance of the civil rights movement and federal law. Eagles also paints a remarkable portrait of Meredith himself.

Protein-Ligand Interactions

Автор: Mark A. Williams; Tina Daviter
Название: Protein-Ligand Interactions
ISBN: 1493958739 ISBN-13(EAN): 9781493958733
Издательство: Springer
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Цена: 23058.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: In its revised 2nd Edition, this Methods in Molecular Biology (TM) book provides a complete introduction to common and emerging procedures for characterizing the interactions of individual proteins. Offers materials lists, reproducible protocols, notes and more.

DNA-Ligand Interactions

Автор: W. Guschlbauer
Название: DNA-Ligand Interactions
ISBN: 1468453858 ISBN-13(EAN): 9781468453850
Издательство: Springer
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Цена: 6986.00 р.
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Описание: This volume contains the texts of the nineteen lectures presented at the NATO-ASI - FEBS Course on "DNA - ligand interactions: from drugs to proteins." Italy in May 1981 and which was published in the NATO ASI Life Science series as volume 45. Some of the contributions at the ASI presented the most recent advances in this e>:citing field.

Death Receptors and Cognate Ligands in Cancer

Автор: Holger Kalthoff
Название: Death Receptors and Cognate Ligands in Cancer
ISBN: 3642260764 ISBN-13(EAN): 9783642260766
Издательство: Springer
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Цена: 36197.00 р.
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Описание: Death receptors play a central role in directing apoptosis in mammalian cells. This book explores the molecular basis of death receptor signaling and their role in cancer development.

Self-Assembled Molecules – New Kind of Protein Ligands

Автор: Irena Roterman; Leszek Konieczny
Название: Self-Assembled Molecules – New Kind of Protein Ligands
ISBN: 3319880713 ISBN-13(EAN): 9783319880716
Издательство: Springer
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Цена: 6986.00 р.
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Описание:

The subject of this book relates to protein ligands with particular structural and complexation properties. They are composed of self-assembled molecules, capable of penetrating as a unit into proteins outside the binding site. The ribbon-like supramolecular system only permits the penetration of self-assembled molecules into the protein-body and formation of stable complexes. Supramolecular Congo red and similar compounds fit these requirements. Destabilized protein fragments enable the penetration of such ligands, with susceptibility to supramolecular ligand binding often associated with protein function. As a result, complexation modifies their functional effects. The activity of enzymes is inhibited by arresting them in the complexed state, but “naturally irreversible” complexation as in the case of immune complexation, is enhanced instead. This property offers many attractive possibilities of using supramolecular ligands as described in this book. This book is an open access under a CC BY license.
Metal Complexes with Tetrapyrrole Ligands II

Автор: Laura A. Andersson; Johann W. Buchler; John H. Daw
Название: Metal Complexes with Tetrapyrrole Ligands II
ISBN: 3662150034 ISBN-13(EAN): 9783662150030
Издательство: Springer
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Цена: 6986.00 р.
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Computational Biophysics of Membrane Proteins

Автор: Domene Carmen
Название: Computational Biophysics of Membrane Proteins
ISBN: 1782624902 ISBN-13(EAN): 9781782624905
Издательство: Royal Society of Chemistry
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Цена: 37805.00 р.
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Описание: Exploring current themes in modern computational and membrane protein biophysics, this book is ideal for researchers in computational chemistry and computational biophysics.


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