Advances in Stem Cell Therapy: Bench to Bedside, El-Badri Nagwa
Автор: El-Badri Название: Advances in Stem Cell Therapy ISBN: 3319291475 ISBN-13(EAN): 9783319291475 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The book reviews the main approaches for generation of differentiated cells from various types of stem cells, including embryonic, placental and cord blood stem cells through marrow, adipose tissue and dental pulp. The book starts with an overview of experimental protocols applied to generate insulin secreting cells, neural cells, heart cells, and other tissue specific cells ex vivo and in experimental animals. This is followed by exhaustive review of clinical trials in these pathologies. It continues with a comparison of the merits of successful transplantation in humans versus animal experimentation, and highlights the most promising clinical applications in the field. Special chapters are devoted to the topic of tissue engineering and modern synthetic and biological scaffolds. It is essential reading for scientists and researchers in tissue engineering and stem cell research as well as clinicians who are involved in developing or testing stem cell therapies.
Автор: Indumathi Somasundaram Название: Stem Cell Therapy for Organ Failure ISBN: 8132221095 ISBN-13(EAN): 9788132221098 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The book “STEM CELL THERAPY FOR ORGAN FAILURES” edited by Dr. S. Indumathi demonstrates the In Vitro and In vivo therapeutic strategies and applications of pre- and post-natal stem cells for treating the failures of various organ systems of our body in a wide perspective. It explores the past, present and the futuristic approach of the exciting field of stem cells and its intriguing properties involved in tissue repair and regeneration. The prime focus of this volume is to unravel the basic, advanced, therapeutic and translational approaches put-forth so far in the field of stem cells and regenerative medicine at research, pre-clinical and clinical levels. Stem cells has ushered in widespread interest and exciting possibilities for cell based therapies, albeit failures do prevail and small uncontrolled phase I/II studies are only signals generating, rather than definite proof of concept thereby limiting its applicability in curative therapeutics. Despite certain initiatives and meticulous untiring efforts, bringing this basic bench side research into advanced transitional bedside remained a challenge. Thus, this book embarked upon the expanding researches in these areas that seem decisive in improvising regenerative medical therapeutics, thereby leading to further path-breaking studies that cure all health challenges facing mankind. Overall, this book reveals the imperativeness of various stem cell sources and its utility in curative therapeutics.
Автор: Mohamed Al-Rubeai; Mariam Naciri Название: Stem Cells and Cell Therapy ISBN: 9400771959 ISBN-13(EAN): 9789400771956 Издательство: Springer Рейтинг: Цена: 19591.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: It includes chapters on neural and vascular stem vascular stem cell therapy, expansion engineering of embryonic stem cells, stem cell based production of blood cells and separation technologies for stem cells and cell therapy products.
Автор: Jaap Jan Boelens; Robert Wynn Название: Stem Cell Therapy in Lysosomal Storage Diseases ISBN: 1493948881 ISBN-13(EAN): 9781493948888 Издательство: Springer Рейтинг: Цена: 19589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume discusses the history, current practice and future perspectives of stem cell in inborn errors of metabolism and provides an international perspective on progress, limitations, and future directions in the field.
Автор: Han Fabin, Lu Pengzhe (Paul) Название: Stem Cell-Based Therapy for Neurodegenerative Diseases ISBN: 9811543690 ISBN-13(EAN): 9789811543692 Издательство: Springer Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book reviews the state-of-the-art in stem-cell-based therapies for neurodegenerative diseases, and highlights advances in both animal models and clinical trials.
Автор: Boelens Jaap Jan Название: Stem Cell Therapy in Lysosomal Storage Diseases ISBN: 1461483565 ISBN-13(EAN): 9781461483564 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume discusses the history, current practice and future perspectives of stem cell in inborn errors of metabolism and provides an international perspective on progress, limitations, and future directions in the field.
Автор: Pandey Tarun Название: Imaging in Stem Cell Transplant and Cell-Based Therapy ISBN: 331984752X ISBN-13(EAN): 9783319847528 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides a review of imaging techniques and applications in stem cell transplantation and other cell-based therapies. Essential reading for radiologists and physicians who are interested in developing a basic understanding of stem cell imaging and applications of stem cells and cell based therapies.
Автор: Tarun Pandey Название: Imaging in Stem Cell Transplant and Cell-based Therapy ISBN: 3319518313 ISBN-13(EAN): 9783319518312 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides a review of imaging techniques and applications in stem cell transplantation and other cell-based therapies. Essential reading for radiologists and physicians who are interested in developing a basic understanding of stem cell imaging and applications of stem cells and cell based therapies.
Автор: Brian G. Ballios; Michael J. Young Название: Regenerative Medicine and Stem Cell Therapy for the Eye ISBN: 3319980793 ISBN-13(EAN): 9783319980799 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This book provides an overview of the types, sources, and applications of stem cells in regenerating various ocular tissues, with a perspective on both potential applications of stem cells and possible challenges. The scope of the chapters include both preclinical and clinical applications, including stem cell-derived therapies based on endogenous tissue repair; stem cell transplantation and cell replacement therapy; gene therapy; and in vitro disease modelling. Additionally, the volume presents applications in both anterior and posterior ocular disease, with a particular focus on diseases of the ocular surface, cornea, limbus, and retina, including inherited retinal dystrophies as well as acquired diseases, such as age-related macular degeneration. Regenerative Medicine and Stem Cell Therapy for the Eye is an ideal book for advanced researchers in stem cell and ocular biology as well as clinical ophthalmologists, and will be of interest to readers with backgrounds in developmental biology and bioengineering.
This book also
Skillfully reviews cutting-edge advances in stem cell biology as applied to regenerative medicine and ocular diseaseProvides expert viewpoints on key hurdles and challenges to successful implementation of stem cell-derived therapies in the clinical domainOffers a multi-disciplinary, broad understanding of cell-based therapies for ocular diseases by incorporating perspectives from biomedical scientists, physicians, and engineersExamines the connection between cell therapy and gene editing, in particular relation to ocular disease
Автор: Nicole I. Nieden Название: Embryonic Stem Cell Therapy for Osteo-Degenerative Diseases ISBN: 1493957236 ISBN-13(EAN): 9781493957231 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this dependable and cutting-edge book, accomplished investigators provide detailed descriptions on how to expand ESCs from the most commonly used species ex vivo, i.e. mouse and human, in static culture as well as in controllable bioreactor processes.
Автор: Hossein Baharvand; Nasser Aghdami Название: Advances in Stem Cell Research ISBN: 1627039589 ISBN-13(EAN): 9781627039581 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume covers biomanufacturing iPS cells for therapeutic applications, techniques for controlling stem cell fate decisions, along with current basic research in such areas as germ line stem cells, genomics and proteomics in stem cell research.
Автор: Lucas G. Chase; Mohan C Vemuri Название: Mesenchymal Stem Cell Therapy ISBN: 1627039147 ISBN-13(EAN): 9781627039147 Издательство: Springer Рейтинг: Цена: 21661.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field.
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