Stem Cell-Based Therapy for Neurodegenerative Diseases, Han Fabin, Lu Pengzhe (Paul)
Автор: Daniela Galimberti; Elio Scarpini Название: Neurodegenerative Diseases ISBN: 1447172426 ISBN-13(EAN): 9781447172420 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book gives an overview of the current knowledge on the most common neurodegenerative diseases, including Alzheimer`s disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and additional neurodegenerative diseases.
Metabolic Drivers and Bioenergetic Components of Neurodegenerative Disease reviews how the different aspects of metabolic dysfunction and consequent pathology associated with neurodegenerative diseases, including Alzheimer's and Parkinson's, can be targeted by novel treatment approaches. Topics covered include Cellular Senescence in Aging and Age-Related Disorders: Implications for Neurodegenerative Diseases; Repurposing GLP1 agonists for Neurodegenerative Diseases; Ketotherapeutics for Neurodegenerative Diseases; Enhancing Mitophagy as a Therapeutic Approach for Neurodegenerative Diseases; Harnessing Neurogenesis in the Adult Brain - A Role in Type 2 Diabetes Mellitus and Alzheimer's disease; and much more.
Автор: Philip Beart; Michael Robinson; Marcus Rattray; Ni Название: Neurodegenerative Diseases ISBN: 3319860992 ISBN-13(EAN): 9783319860992 Издательство: Springer Рейтинг: Цена: 39130.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Provides a timely overview of critical advances in molecular and cellular neurobiology, covers key methodologies driving progress, and highlights key future directions for research on neuronal injury and neurodegeneration relevant to neuronal brain pathologies.
Автор: Marie-Francoise Chesselet Название: Molecular Mechanisms of Neurodegenerative Diseases ISBN: 1617371971 ISBN-13(EAN): 9781617371974 Издательство: Springer Рейтинг: Цена: 34799.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The field ofneurodegenerative diseases is undergoing an unprecedented revolution. The past decade has seen the identification of new mutation mecha- nisms, such as triplet repeat expansions, and new genes causing familial forms of common neurodegenerative diseases, such as Parkinson's and Alzheimer's diseases. Cellular and animal models based on this genetic information are now available and, importantly, common mechanisms are rapidly emerging among diseases that were once considered unrelated. The field is poised for the development of new therapies based on high throughput screenings and a bet- ter understanding of the molecular and cellular mechanisms leading to neurodegeneration. Molecular Mechanisms of Neurodegenerative Diseases reviews recent progress in this exploding field. By nature, such a book cannot be all inclu- sive. It focuses on Alzheimer's, Parkinson's, and CAG triplet repeat diseases. In the first chapter, Bill Klein reviews the role of A toxicity in the patho- physiology of Alzheimer's disease. This controversial issue is further exam- ined in the context of transgenic models of Alzheimer's disease by LaFerla and colleagues. Sue Griffin and Robert Mrak, and Caleb Finch and collabora- tors, then examine the role of glial cells and inflammation in Alzheimer's disease; a review of the role of proteolysis in the generation of abnormal pro- tein fragments by Hook and Mende-Mueller follows. Therapeutic opportuni- ties offered by a better understanding of Alzheimer's disease pathophysiology are examined by Perry Molinoff and his colleagues at Bristol-Myers Squibb.
Автор: Mathias Jucker; Yves Christen Название: Proteopathic Seeds and Neurodegenerative Diseases ISBN: 3642446965 ISBN-13(EAN): 9783642446962 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book details the latest research on prion diseases and presents developing therapies. It includes contributions from Nobel Laureates Eric Kandel and Stanley Prusiner.
Автор: Aschner, Michael Название: Environmental Factors in Neurodegenerative Diseases ISBN: 0128127643 ISBN-13(EAN): 9780128127643 Издательство: Elsevier Science Рейтинг: Цена: 25265.00 р. Наличие на складе: Поставка под заказ.
Описание:
Environmental Factors in Neurodegenerative Diseases, Volume One addresses contemporary advances in neurotoxicology, with thematic volumes providing authoritative review articles on key issues in the field. Edited by leading subject experts, volumes are designed as in-depth overviews of the latest topic developments that analyze the effect of varied chemical agents on the nervous system. As a result, this serial is an essential and unique resource for researchers and graduate students alike.
Includes, in one single publication, a selection of comprehensive reviews devoted to neurotoxicology
Edited by high-profile, leading academics in the field, ensuring a quality publication for subscribers
Aims to widen the scope for participation by international contributors, researchers and editorial board members outside North America
Serves a broad audience of university faculty, researchers and students, as well as the industry, drug development companies and the government
Описание: Neurodegenerative diseases are characterized by chronic and progressive loss of neurons in discrete areas of the brain. This book presents cutting-edge, comprehensive information on the molecular aspects of acute neural trauma and neurodegenerative diseases.
Автор: Mahendra Rai; Alka Yadav Название: Nanobiotechnology in Neurodegenerative Diseases ISBN: 3030309290 ISBN-13(EAN): 9783030309299 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book focuses on neurodegenerative diseases which have become a major threat to human health. Neurodegenerative diseases are age related disorders and have become increasingly prevalent in the elderly population in recent years. Hence, there is an urgent need to study and develop new strategies and alternative methods for the treatment of neurodegenerative diseases. This book showcases the promises that nanobiotechnology brings in research, diagnosis, and treatment of neurodegenerative diseases. It is very beneficial for varied group of readers including nanotechnologists, biotechnologists, pharmacists, medical professionals, bioengineers, biochemists and researchers working in this field. Nanobiotechnology in Neurodegenerative Diseases include various chapters including neurodegeneration and neurodegenerative diseases, nanotechnology for the rescue of neurodegenerative diseases, promising potential of nanomaterials for diagnosis and therapy of neurodegenerative diseases, nanotechnology mediated nose-to-brain drug delivery, and formulation and characterization of intranasal nanoparticles of antiretroviral drugs.
1. What is this book series about? Foreword of Book Series Editor; O. Golubnitschaja
2. Preface; S. Mandel
3. Introductory chapter; S. Mandel and O. Golubnitschaja
Part II
4. Individual predispositions in healthy vasospastic individuals: Patient profiling for targeted prevention of "down-stream" pathologies as cost-effective personalised medicine; K. Yeghiazaryan, J. Flammer, O. Golubnitschaja
5. Idiopathic REM sleep behavior disorder as a long-term predictor of neurodegenerative disorders; S. Fulda and M. Manconi
6. New animal models of progressive neurodegeneration: tools for developing predictive diagnostics and identifying presymptomatic therapeutic targets; A. L. Marriott, D. A. Gill, C. A. Shaw, R. A. Tasker
7. Tau pathology: A selected view on the current status; I. Gozes
Part III
8. The Use of Biomarkers for Prediction and Prevention of Alzheimer's and Parkinson's Diseases; S. A. Mandel & A. D. Korczyn
9. Making clinical trials of Alzheimer's disease delay-of-onset a reality by use of a prognostic genetic biomarker; Iris Grossman
10. An update on CSF biomarkers of Parkinson's disease; Peter LeWitt, B Russell Huber, Jing Zhang
Part IV
11. Glaucomatous optic neuropathy: Risk assessment and potential targets for effective prevention and treatments tailored to the patient; O. Golubnitschaja, K. Yeghiazaryan, J. Flammer
Part V
12. Toward a personalized approach in amyotrophic lateral sclerosis: new developments in diagnosis, genetics, pathogenesis and therapies; B. Nefussy & V. E. Drory
13. Recent advances in ALS research: perspectives for personalized clinical application; C. Benkler, D. Offen, E. Melamed, T. Amit, S. Mandel, M. B.H. Youdim, O. Weinreb
Part VI
14. Exercise in Multiple Sclerosis - an Integral Component of Disease Management; A. Dцring, C. F. Pfueller, F. Pau, J. Dцrr
15. Bridging the Informatics Gap between Bench and Bedside: Implications to Neurodegenerative Diseases; A. Shabo (Shvo) & M. Scarpa
Part VII
16. Personalized Medicine In Rare Paediatric Neurometabolic Diseases; R. Tomanin, C. M. Bellettato, F. D'Avanzo, A. Zanetti, A. Ceci, D. Begley, M. Scarpa
Автор: Judit Ov?di; Ferenc Orosz Название: Protein folding and misfolding: neurodegenerative diseases ISBN: 9048181275 ISBN-13(EAN): 9789048181278 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Offering all the latest in the study of neurodegenerative diseases, this book reviews the molecular events initiated by unfolded or misfolded proteins leading to conformational human diseases, especially those found in Parkinson`s and Alzheimer`s diseases.
Автор: Essa M. Mohamed, Akbar Mohammed, Guillemin Gilles Название: The Benefits of Natural Products for Neurodegenerative Diseases ISBN: 3319803409 ISBN-13(EAN): 9783319803401 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Focuses on the effects of natural products and their active components on brain function and neurodegenerative disease prevention. Phytochemicals such as alkaloids, terpenes, flavanoids, isoflavones, saponins etc are known to possess protective activity against many neurological diseases. The molecular mechanisms behind the curative effects rely mainly on the action of phytonutrients on distinct signaling pathways associated with protein folding and neuro-inflammation. The diverse array of bioactive nutrients present in these natural products plays a pivotal role in prevention and cure of various neurodegenerative diseases, disorders, or insults, such as Alzheimer's Disease, Parkinson's Disease, Huntington's Disease, traumatic brain injury, and other neuronal dysfunctions. However, the use of these antioxidants in the management of neurodegenerative conditions has so far been not well understood. This is a comprehensive collection addressing the effects on the brain of natural products and edible items such as reservatrol, curcumin, gingerol, fruits, vegetables, nuts, and marine products.
Описание: Researchers seeking problems that offer more hope of success often avoid subjects that seem to be difficult to approach experimentally, or subjects for which experimental results are difficult to interpret.
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