This unique advanced textbook provides a clear and comprehensive overview of gene delivery, gene therapy and genetic pharmacology, with descriptions of the main gene transfer vectors and a set of selected therapeutic applications, along with safety considerations. The second edition features new groundbreaking material on genome editing using the recently discovered CRISPR/Cas9 system and on cancer immunotherapy by CAR-T cells. It also presents the historical milestone of gene therapy application in the field of severe combined immunodeficiency, and other fields of gene therapy and molecular medicine.
The use of gene transfer is exponentially growing in the scientific and medical communities for day-to-day cell biology experiments and swift development of gene therapy, which is already revolutionizing medicine. In this advanced textbook, more than 30 leading scientists come together to explore these topics.
This educational introduction provides the background material needed to further explore the subject as well as relevant research literature. It is an invaluable resource to Master, PhD or MD students, post-doctoral scientists or medical doctors, as well as any scientist wishing to deliver a gene or synthetic nucleotide or develop a gene therapy strategy. The second edition's simple and synthetic content will be of value to any reader interested in the biological and medical revolution derived from the elucidation of the human genome.
Автор: Sheefali Mahant, Rekha Rao, Sanju Nanda Название: Advanced Drug Delivery Systems: Principles and Practice ISBN: 9386768569 ISBN-13(EAN): 9789386768568 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 3604.00 р. Наличие на складе: Нет в наличии.
Описание: Divided in eleven chapters, the book broadly deals with advanced drug delivery systems, preformulation studies, experimental design, basic experimental procedures in advanced drug delivery systems, and delivery systems designed for different routes of drug administration.
Автор: Nayak Amit Kumar, Hasnain MD Saquib Название: Advanced Biopolymeric Systems for Drug Delivery ISBN: 3030469220 ISBN-13(EAN): 9783030469221 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In the lively, but desperate world of D.C.`s underbelly, filled with back-alley deals, gentrification clashes, and unexpected encounters between politicians and bottom-rung natives-all set against a soundscape of patois, street Spanish, and D.C. slang-a Black homeless man must hone his detective skills before he is punished for a brutal crime he didn`t commit.
Автор: Brown, Dennis M. Название: Drug Delivery Systems In Cancer Therapy ISBN: 0896038882 ISBN-13(EAN): 9780896038882 Издательство: Springer Рейтинг: Цена: 30039.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Leading experts survey the currently available technologies designed to improve the delivery of today's cancer chemotherapeutic agents. The authors review both the theoretical and practical considerations governing conventional and nonconventional methods of drug administration, and identify promising opportunities for product development. In their outline and discussion of the use of novel formulation technologies-including synthetic polymers and biomaterials for prolonged or sustained drug release to achieve potentially greater therapeutic effect-they profile those technologies that have resulted in a number of approved and late-stage clinical products.
Описание: Nanotechnology-based Targeted Drug Delivery Systems for Lung Cancer is an indispensable resource that will help pharmaceutical scientists and clinical researchers design and develop novel drug delivery systems and devices for the treatment of lung cancer. As recent breakthroughs in nanomedicine are now making it possible to deliver drugs, genes and therapeutic agents to localized areas of disease to maximize clinical benefit, while also limiting unwanted side effects, this book explores promising approaches for the diagnosis and treatment of lung cancer using cutting-edge nanomedical technologies. Topics discussed include polymeric nanoparticles, solid lipid nanoparticles, liposomes, dendrimers, micelles and nanoemulsions.
Название: Nanoparticle Drug Delivery Systems for Cancer Treatment ISBN: 9814800546 ISBN-13(EAN): 9789814800549 Издательство: Taylor&Francis Рейтинг: Цена: 17762.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book compiles and details cutting-edge research in nanomedicine from an interdisciplinary team of international cancer researchers, who are currently revolutionizing drug delivery techniques through the development of nanomedicines and nanotheranostics.
Автор: Matsumura Yasuhiro, Tarin David Название: Cancer Drug Delivery Systems Based on the Tumor Microenvironment ISBN: 4431568786 ISBN-13(EAN): 9784431568780 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book proposes the importance of new systems of drug design and delivery based on cancer pathophysiology in addition to cancer molecular and cellular biology.
Bioceramics play an important role in repairing and regenerating defective or damaged bone. Annually, more than 500,000 bone graft procedures are performed in the United States and approximately 2.2 million are conducted worldwide. Advanced Bioactive Inorganic Materials for Bone Regeneration and Drug Delivery reviews the latest advances in the field of bioceramics. The book summarizes innovative concepts, bioceramic design, and methods for material synthesis and drug delivery.
Offering guidance for biomedical engineering researchers and material scientists, the book explores:
Novel mesoporous bioactive glasses and silicate-based ceramics for bone regeneration and drug delivery
Bioactive silicate ceramics, including their mechanical properties, interaction with bone-forming cells, and in vivo osteogenesis and angiogenesis
Silica nanospheres with a core-shell structure and their specific properties for controllable drug delivery
The 3D-printing technique to prepare advanced bioceramic scaffolds for bone tissue engineering applications--including the preparation, mechanical strength, and biological properties of 3D-printed porous scaffolds of calcium phosphate cement and silicate bioceramics
Biomimetic preparation and controllable crystal growth and biomineralization of bioceramics
Inorganic and organic composite materials and their unique biological, electrical, and mechanical properties that enable the design of excellent bone regeneration and gene delivery systems
A comprehensive survey of the research progress of bioceramics and their applications in bone repair and regeneration, this volume is designed to enhance study and career development for those in this field and to facilitate further research and opportunities for new solutions.
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