Mitochondrial Regulation: Methods and Protocols, Palmeira Carlos M., Rolo Anabela P.

Автор: Orrenius
Название: Mitochondrial Signaling in Health and Disease
ISBN: 1439880026 ISBN-13(EAN): 9781439880029
Издательство: Taylor&Francis
Рейтинг:
Цена: 29093.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание:

Mitochondria have traditionally been associated with metabolic functions; however recent research has uncovered a central role for these organelles in cell signaling, cell survival, and cell death. Mitochondrial dysfunction is a factor in a myriad of pathophysiological conditions, including age-related neurodegenerative disorders, cancer, metabolic syndrome, and cardiovascular disease. Mitochondrial Signaling in Health and Disease examines themes essential for the maintenance of the mitochondrial redox (reduction-oxidation) energy axis.

Автор: Peter Sutovsky
Название: Cellular and Molecular Basis of Mitochondrial Inheritance
ISBN: 3030045692 ISBN-13(EAN): 9783030045692
Издательство: Springer
Рейтинг:
Цена: 15372.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This new volume of our successful book series Advances in Anatomy, Embryology and Cell Biology is focused on mitochondrial inheritance in humans and both vertebrate and invertrebate animals including Drosophila, C. elegans, bivalve molusc Mytilus and livestock mammals. Special consideration is given to cellular mechanisms promoting uniparental inheritance of mitochondria and mitochondrial genes, evolutionary perspectives, and biomedical and epidemiological considerations. Contributed by five distinguished mitochondrial research teams from around the world, this volume will target a wide audience of physiologists, anatomists, cell, and developmental and evolutionary biologists, as well as physicians, veterinarians, livestock specialists and biomedical researchers.

Автор: Gaetano Santulli
Название: Mitochondrial Dynamics in Cardiovascular Medicine
ISBN: 3319856308 ISBN-13(EAN): 9783319856308
Издательство: Springer
Рейтинг:
Цена: 25155.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This text covers the basic principles of mitochondrial dynamics in cardiovascular medicine, with particular emphasis on their functional roles in physiology and disease. The book will include articles pertaining to mitochondrial fitness on a global basis, providing therefore an update on the progress made in several aspects in the field. Thus, it will assist scientists and clinicians alike in furthering basic and translational research. Organized in sections focusing on: basic science, mitochondrial dysfunction in cardiac disorders, in vascular disorders, in metabolic disorders, in kidney disease, therapeutic challenges and options, this essential volume fills imperative gaps in understanding and potentially treating several cardiovascular disorders.

Автор: Volkmar Weissig; Marvin Edeas
Название: Mitochondrial Medicine
ISBN: 1493922874 ISBN-13(EAN): 9781493922871
Издательство: Springer
Рейтинг:
Цена: 20962.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This expert volume covers an interdisciplinary and rapidly growing area of biomedical research comprising genetic, biochemical, pathological, and clinical studies aimed at the diagnosis and therapy of human diseases which are either caused by or associated with mitochondrial dysfunction.

Автор: Sanders Thomas Wayne
Название: The Bonnie Code: One girl`s battle with mitochondrial disease, using joy as her armor
ISBN: 1631293672 ISBN-13(EAN): 9781631293672
Издательство: Неизвестно
Рейтинг:
Цена: 2137.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание:

"A treasure of a book.We trust it will inspireand encourage many as it did us."Jan Marie, Joni and FriendsThe Bonnie Code is based on the true story of Bonnie Codier, her family and her friendship with a Bonnie-Sitter over a four-year period. It illuminates the complexity of mitochondrial disease, while offering a heart-warming story of a families' attitude of gratitude in the face of constant physical struggle - along with real examples of how the Grace of God and His Plan can shine in our lives and in those around us - no matter our condition. Tom Sanders is the Contracts Sr. Administrator for SPVAP (Surgical & Procedural Value & Alignment Program) at Banner Health, Phoenix, Arizona. Raised in Oklahoma, he relocated to Arizona in 1986, where he currently resides, playing tennis and golf as much as work will allow, as well as spending time in the aromatic pines of Northern Arizona with his wife, Kimberly. Together, they enjoy keeping up with five grown children between them, a growing number of wonderful grandchildren and their dainty dachshund, Stella.

Автор: Minczuk Michal, Rorbach Joanna
Название: Mitochondrial Gene Expression: Methods and Protocols
ISBN: 1071608339 ISBN-13(EAN): 9781071608333
Издательство: Springer
Рейтинг:
Цена: 18167.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Authoritative and cutting-edge, Mitochondrial Gene Expression: Methods and Protocols aims to provide complementary approaches and practical guidelines. Chapter 7 is available Open Access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Автор: Carlos M. Palmeira; Anabela P. Rolo
Название: Mitochondrial Regulation
ISBN: 1493946129 ISBN-13(EAN): 9781493946129
Издательство: Springer
Рейтинг:
Цена: 13974.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание:

1. Isolation of Crud Mitochondrial Fraction from Cells

Mariusz R. Wieckowski and Lech Wojtczak

2. Isolation of Mitochondria from Liver and Extraction of Total RNA and Protein - Analyses of MicroRNA and Protein Expressions

Pedro M. Borralho, Clifford J. Steer, and Cecнlia M. P. Rodrigues

3. PCR Based Determination of Mitochondrial DNA Copy Number in Multiple Species

Rooney JP, Ryde IT, Sanders LH, Howlett EH, Colton MD, Germ KE, Mayer GD, Greenamyre JT, and Meyer JN

4. NAD⁺ Content and its Role in Mitochondria

Wei Li and Anthony A. Sauve

5. Measuring PGC-1α and its Acetylation Status in Mouse Primary Myotubes

Ana P. Gomes and David A. Sinclair

6. Measurement of Mitochondrial Oxygen Consumption Rates in Mouse Primary Neurons and Astrocytes

Sofia M. Ribeiro, Alfredo Gimйnez-Cassina, and Nika N. Danial

7. Determination Of Oxidative Phosphorylation Complexes Activities

Joгo S. Teodoro, Carlos M. Palmeira, and Anabela P. Rolo

8. Histoenzymatic Methods for Visualization of the Activity of Individual Mitochondrial Respiratory Chain Complexes in the Muscle Biopsies from Patients with Mitochondrial Defects

Agnieszka Karkucinska-Wieckowska, Maciej Pronicki, and Mariusz R. Wieckowski

9. A Method Aimed at Assessing the Functional Consequences of the Supramolecular Organization of the Respiratory Electron Transfer Chain by Time-resolved Studies

Fabrice Rappaport

10. BN-PAGE-based Approach to Study Thyroid Hormones and Mitochondrial Function

Elena Silvestri, Assunta Lombardi, Federica Cioffi, and Fernando Goglia

11. Detection of UCP1 Protein and Measurements of Dependent GDP-Sensitive Proton Leak in Non-Phosphorylating Thymus Mitochondria

Kieran J. Clarke, Audrey M. Carroll, Gemma O'Brien & Richard K. Porter

12. Exploring Liver Mitochondrial Function By ¹³c-Stable Isotope Breath Tests. Implications In Clinical Biochemistry

Ignazio Grattagliano, Leonilde Bonfrate, Michele Lorusso, Luigi Castorani, Ornella de Bari, and Piero Portincasa

13. Following Mitochondria Dynamism: Confocal Analysis of The Organelle Morphology

F. R. Mariotti, M. Corrado, and S. Campello

Автор: Carlos M. Palmeira; Anabela P. Rolo
Название: Mitochondrial Regulation
ISBN: 1493918745 ISBN-13(EAN): 9781493918744
Издательство: Springer
Рейтинг:
Цена: 19564.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Автор: Buhlman Lori M.
Название: Mitochondrial Mechanisms of Degeneration and Repair in Parkinson`s Disease
ISBN: 3319825070 ISBN-13(EAN): 9783319825076
Издательство: Springer
Рейтинг:
Цена: 25155.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This volume brings together various theories of how aberrations in mitochondrial function and morphology contribute to neurodegeneration in idiopathic and familial forms of Parkinson’s disease. Moreover, it comprehensively reviews the current search for therapies, and proposes how molecules are involved in specific functions as attractive therapeutic targets. It is expected to facilitate critical thought and discussion about the fundamental aspects of neurodegeneration in Parkinson’s disease and foster the development of therapeutic strategies among researchers and graduate students. Theories of idiopathic Parkinson’s etiology support roles for chronic inflammation and exposure to heavy metals or pesticides. Interestingly, as this project proposes, a case can be made that abnormalities in mitochondrial morphology and function are at the core of each of these theories. In fact, the most common approach to the generation of animal and cell-culture models of idiopathic Parkinson’s disease involves exposure to mitochondrial toxins. Even more compelling is the fact that most familial patients harbor genetic mutations that cause disruptions in normal mitochondrial morphology and function. While there remains to be no effective treatment for Parkinson’s disease, efforts to postpone, prevent and “cure” onset mitochondrial aberrations and neurodegeneration associated with Parkinson’s disease in various models are encouraging. While only about ten percent of Parkinson’s patients inherit disease-causing mutations, discovering common mechanisms by which familial forms of Parkinson’s disease manifest will likely shed light on the pathophysiology of the more common idiopathic form and provide insight to the general process of neurodegeneration, thus revealing therapeutic targets that will become more and more accessible as technology improves.

Автор: Carlos M. Palmeira; Ant?nio J. Moreno
Название: Mitochondrial Bioenergetics
ISBN: 1493958372 ISBN-13(EAN): 9781493958375
Издательство: Springer
Рейтинг:
Цена: 20263.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This Methods in Molecular Biology (TM) book offers practical principles and assays designed to derive quantitative assessment of each set of parameters that reflect different aspects of mitochondrial bioenergetics. Includes protocols, materials lists and tips.