The Role of Glycosylation in Health and Disease, Lauc Gordan, Trbojevic-Akmačic Irena

Автор: Davey Gavin
Название: Glycosylation: Methods and Protocols
ISBN: 1071616846 ISBN-13(EAN): 9781071616840
Издательство: Springer
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Цена: 18167.00 р.
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Описание: This volume explores the latest techniques and methods used for performing up-to-date glycosylation research. The chapters in this book are organized into four parts. Part One looks at the latest analytical and bioinformatics technologies that enable the characterization of glycosylation complexity. Part Two details the importance of synthetic chemistry and glycoengineering in the fields of bioprocessing and biotherapeutic development. Part Three discusses systems biology and computational technologies used by scientists to analyze glycosylation events in the cell. Part Four focuses on how cellular glycosylation biomarkers can be identified and used to characterize human clinical datasets. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Glycosylation: Methods and Protocols is a valuable resource for any scientist or researcher interested in learning more about this exciting and developing field.

Автор: Walter H. Horl
Название: PROTEASES: Potential Role in Health and Disease
ISBN: 1461593573 ISBN-13(EAN): 9781461593577
Издательство: Springer
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Цена: 6986.00 р.
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Автор: Michelle L. Gumz
Название: Circadian Clocks: Role in Health and Disease
ISBN: 1493980548 ISBN-13(EAN): 9781493980543
Издательство: Springer
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Цена: 16070.00 р.
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Описание: This book sheds new light on the molecular mechanisms that generate circadian rhythms. It examines how biological rhythms influence physiological processes such as sleep, hormone synthesis and secretion, immunity, kidney function, the cardiovascular system, blood pressure, and the digestive system. Clinical implications are considered while exploring the impact of rhythms on neuropsychiatric disorders and chronotherapy’s potential for reducing cardiovascular risk. Offering a cross-section of expertise in both basic and translational (bench-to-bedside) research, this book serves as a guide for physicians and scientists who wish to learn more about the impact of circadian rhythms on physiological processes in health and disease.

Автор: Praetorius Jeppe, Blazer-Yost Bonnie, Damkier Helle
Название: Role of the Choroid Plexus in Health and Disease
ISBN: 1071605356 ISBN-13(EAN): 9781071605356
Издательство: Springer
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Цена: 13974.00 р.
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Описание: This book highlights the importance of the choroid plexus, which forms the blood-cerebrospinal fluid barrier and is the site of the major production of the cerebrospinal fluid (CSF).

Автор: Mohammed Al-Rubeai
Название: Glycosylation
ISBN: 9048160685 ISBN-13(EAN): 9789048160686
Издательство: Springer
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Цена: 23508.00 р.
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Описание: This book provides a unique and up-to-date insight into the biopharmaceutical industry. Largely written by industrial authors, its scope is multidisciplinary, rendering it an ideal reference source for students undertaking advanced undergraduate or postgraduate courses in biotechnology, pharmaceutical science, biochemistry, or medicine.

Автор: Roslyn M. Bill; Leigh Revers; Iain B.H. Wilson
Название: Protein Glycosylation
ISBN: 0792383370 ISBN-13(EAN): 9780792383376
Издательство: Springer
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Цена: 36570.00 р.
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Описание: Presents an overview of the chemical structures of mono- and oligosaccharides. This book includes discussions on the purification, function, and enzyme kinetics of selected glycosidases and glycotransferases, as well as a review of the roles of oligosaccharides in glycoprotein function and the in vivo role of glycoproteins themselves.

Автор: Harold Rifkin; Margo Panush Cohen
Название: Diabetes and Protein Glycosylation
ISBN: 1461293669 ISBN-13(EAN): 9781461293668
Издательство: Springer
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Цена: 14673.00 р.
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Описание: In addition to reviewing a wealth of investigative possibilities in the area of these chronic complications-including eye, kidney, nerve, and vascular disease-Dr. Cohen indicates how enhanced nonenzymatic glycosylation in uncontrolled diabetes underscores the pressing need for maintenance of long-term euglycemia.

Автор: Roslyn M. Bill; Leigh Revers; Iain B.H. Wilson
Название: Protein Glycosylation
ISBN: 1461372410 ISBN-13(EAN): 9781461372417
Издательство: Springer
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Цена: 27950.00 р.
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Описание: Protein Glycosylation provides clear, up-to-date, and integrated coverage of key topics in this field.

Автор: Beck Alain
Название: Glycosylation Engineering of Biopharmaceuticals
ISBN: 1627033262 ISBN-13(EAN): 9781627033268
Издательство: Springer
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Цена: 23757.00 р.
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Описание: This Methods in Molecular Biology(TM) book offers protocols for glycoproteins and glyco-engineered biopharmaceuticals with a focus on mAbs. Covers glyco-engineering of therapeutic proteins, glycoanalytics, glycoprotein complex characterization and PK/PD assays.

Автор: Richard R Drake
Название: Glycosylation and Cancer,126
ISBN: 0128013818 ISBN-13(EAN): 9780128013816
Издательство: Elsevier Science
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Цена: 19875.00 р.
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Описание:

Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics.

Автор: Alain Beck
Название: Glycosylation Engineering of Biopharmaceuticals
ISBN: 1493962663 ISBN-13(EAN): 9781493962662
Издательство: Springer
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Цена: 16769.00 р.
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Описание: Glyco-engineering is being developed as a method to control the composition of carbohydrates and to enhance the pharmacological properties of monoclonal antibodies (mAbs) and other proteins. In Glycosylation Engineering of Biopharmaceuticals: Methods and Protocols, experts in the field provide readers with production and characterization protocols of glycoproteins and glyco-engineered biopharmaceuticals with a focus on mAbs. The volume is divided in four complementary parts dealing with glyco-engineering of therapeutic proteins, glycoanalytics, glycoprotein complexes characterization, and PK/PD assays for therapeutic antibodies. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Glycosylation Engineering of Biopharmaceuticals: Methods and Protocols serves as an ideal guide for scientists striving to push forward the exciting field of engineered biopharmaceuticals.