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Human caspases and neuronal apoptosis in neurodegenerative diseases, Gupta, Anil


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Автор: Gupta, Anil
Название:  Human caspases and neuronal apoptosis in neurodegenerative diseases
ISBN: 9780128201220
Издательство: Elsevier Science
Классификация:
ISBN-10: 0128201223
Обложка/Формат: Paperback
Страницы: 242
Вес: 0.51 кг.
Дата издания: 01.12.2021
Язык: English
Размер: 192 x 235 x 15
Читательская аудитория: Professional & vocational
Ссылка на Издательство: Link
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Поставляется из: Европейский союз
Описание:

Human Caspases and Neuronal Apoptosis in Neurodegenerative Diseases elucidates elaborately the role of caspase enzymes implicated in the initiation of molecular events leading to neuronal apoptosis in the neurodegenerative disease. The book starts with introduction to neuropathology, neurogenetics, and epidemiology of neurodegenerative disease and illustrates the involvement of human caspases, neuronal apoptosis, apoptotic pathways, genetic polymorphisms, and several other factors and underlying mechanisms in the pathology of Alzheimers disease, Parkinsons disease, and Huntingtons disease. An important focus in all chapters is the intricate mechanisms and interplay that occur during or leading to neuron death in neurodegenerative diseases, along with disease pathobiology.




Genotype - Proteotype - Phenotype Relationships in Neurodegenerative Diseases

Автор: Cummings
Название: Genotype - Proteotype - Phenotype Relationships in Neurodegenerative Diseases
ISBN: 3642063950 ISBN-13(EAN): 9783642063954
Издательство: Springer
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Цена: 32004.00 р.
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Описание: Recent advances in understanding the role of protein dysmetabolism in neurodegeneration was the theme of the Fondation IPSEN meeting addressing Genotype-Proteotype-Phenotype relationships.

Neurodegenerative Disorders as Systemic Diseases

Автор: Wada Keiji
Название: Neurodegenerative Disorders as Systemic Diseases
ISBN: 4431562982 ISBN-13(EAN): 9784431562986
Издательство: Springer
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Цена: 20962.00 р.
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Описание: This book sheds new light on neurodegenerative disorders as systemic diseases. Classically, neuronal cell death was a hallmark of such disorders. However, it has become evident that neural dysfunction is more important in the pathophysiology of neurodegenerative disorders. More recently, the prionoid-spreading hypothesis of disease-causing molecules has attracted a great deal of attention. Therapeutic strategies thus must be reconsidered in the light that neurodegenerative disorders are indeed systemic diseases. The first part of this book introduces the concept of neurodegeneration in biology and pathophysiology. The second part focuses on clinical evaluation and biomarkers from the perspective of this new concept, while the third summarizes the risk factors of neurodegeneration. The fourth part of this work indicates future directions of treatment, and the final part discusses health promotion for prevention and quality of life. This book will be of interest to both researchers and medical personnel, and provides a fresh approach to neurodegenerative diseases, paving the way to new research and improved quality of health care for patients.

Neuroglia in Neurodegenerative Diseases

Автор: Verkhratsky
Название: Neuroglia in Neurodegenerative Diseases
ISBN: 9811399123 ISBN-13(EAN): 9789811399121
Издательство: Springer
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Цена: 23757.00 р.
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Описание: This book provides a comprehensive overview of the role of neuroglia in neurodegenerative diseases. Neuroglia are the most abundant cells in the nervous system and consist of several distinct cell types, such as astrocytes, oligodendrocytes,and microglia. Accumulating evidence suggests that neuroglia participate in the neurodegenerative process, and as such are essential players in a variety of diseases, including Alzheimer’s, Parkinson’s, and Huntington’s. Intended for researchers and students, the book presents recent advances concerning the biology of neuroglia as well as their interaction with neurons during disease progression. In addition, to highlight the function of neuroglia in different types of neurodegenerative disease, it also discusses their mechanisms and effects on protecting or damaging neurons.

Adenosine Receptors in Neurodegenerative Diseases

Автор: Blum, David
Название: Adenosine Receptors in Neurodegenerative Diseases
ISBN: 0128037245 ISBN-13(EAN): 9780128037249
Издательство: Elsevier Science
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Цена: 17685.00 р.
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Описание:

Adenosine Receptors in Neurodegenerative Diseases covers the role of adenosine receptors in brain function, also focusing on related methodologies and perspectives in therapeutics. The book provides an up-to-date overview by the best specialists in the field, helping readers consider the importance of adenosine and expand the global impact and visibility of adenosine research in the CNS field.

Chapters include adenosine biology and signaling, gene regulation, control of motor function, and novel adenosine-based therapies in the CNS. It is an ideal resource for researchers, advanced graduate students, clinicians, and industry scientists working in the fields of clinical neuroscience and molecular and cellular neuroscience.

Genedis 2020: Genetics and Neurodegenerative Diseases

Автор: Vlamos Panayiotis
Название: Genedis 2020: Genetics and Neurodegenerative Diseases
ISBN: 3030787869 ISBN-13(EAN): 9783030787868
Издательство: Springer
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Цена: 41925.00 р.
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Описание: 1-Attitudes and smoking prevalence among undergraduate students in central Greece.

2-Care of patients with Alzheimer's disease

3-Regulation of antioxidant enzymes levels in rat brain

4-NIRS-based assessment of cerebral oxygenation during high definition anodal transcranial direct current stimulation in patients with posttraumatic encephalopathy.

5-Cerebral critical closing pressure at concomitant traumatic brain injury.

6-The role of inflammatory biomarkers as a diagnostic tool for possible late-life cognitive decline and dementias

7-The Development of Antisense RNA Treatments using Engineered Protein Substrates

8-Biomarker-driven analysis using high-throughput approaches in neuroinflammation and neurodegenerative diseases

9-Sensitive and Stereo specific high-performance liquid chromatographic method for flurbiprofen in human plasma

10-Genotypic and Clinical Analysis of a Thalassemia Major Cohort: An Observational Study

11-Design and Validation of a New Diagnostic Tool for the Differentiation of Pathological Voices in Parkinsonian Patients

12-Effects of an 8-Week Stress Management Program in Women with Breast Cancer: A Randomized Controlled Trial

13-The Rosenberg Self-Esteem Scale: Translation and Validation in the Greek Language in Adolescents

14-Stress system activation analysis in Greek female adolescents: a bioimpedance study

15-Kisspeptin and the genetic obesity interactome

16-The importance of diagnostic and prognostic biomarkers identification and classification towards understanding ALS pathogenesis.

17-Entropy in Cardiac Autonomic Nervous System of Adolescents with General Learning Disabilities or Dyslexia

18-Ebola virus disease and current therapeutic strategies; A review

19-Hyperbaric Oxygen Therapy effect on "Kinesia Paradoxa" Brain Circuits

20-Early and Very Early GRIM19 and MCL1 Expression are Correlated to Late Acquired Prednisolone Effects in a T-Cell Acute Leukemia Cell Line

21-Phospholipid Fatty Acid Profile of Spirulina platensis

22-Chronic systemic inflammation measured by bioimpedance technology before and after sleeve gastrectomy: a feasibility study

23-Synthesis and Biological Evaluation Substituted Thiophene Derivatives

24-Force spectroscopy in mechanical protein domains unfolding

25-Investigating the genetic component of Parkinson's Disease.

26-Urticaria from the Neurodermatological Perspective: A Temporal Analysis of Urticaria and Cognition

27-Novel Low-Noise CMOS Bioamplifier for the Characterization of Neurodegenerative Diseases

28-The Kentucky Inventory of Mindfulness Skills in Greek Undergraduate and Postgraduate Students

29-Synthesis, in silico stuiesand biological evaluation of 1, 3,4 oxadiazino indole derivatives

30-Designing and screening of new schiff bases of indole derivatives for anti-bacterial activity by in-silico methods and docking studies

31-Use of vitamin D bolus in fortified juice for improving vitamin D status in children with Cerebral Palsy.

32-Microbes and the games they play

33-Impurity Profiling and Identification of 2,6 diisopropylphenol by Raman spectroscopy

34-Cultural Accommodation of the Strengthening Families Program for Parents and Young Adolescents 10-14: Greek Phase I & II Study

35-The effect of nutrients on Alzheimer's disease biomarkers: A metabolomic approach

36-The impact of exercising in the quality of life of people with Aementia-Alzheimer disease

37-Advanced Health Technologies and Nanotechnologies in Neurodegenerative Diseases

38-Phenotype and genotype study in a case of frontometaphyseal dysplasia 1

39-Craniofacial and neurological phenotype in a case of oculodentodigital syndrome

40-Clinical and molecular study of common thrombophilia mutation prothrombin G2
Neurodegenerative Diseases

Автор: Gary Fiskum
Название: Neurodegenerative Diseases
ISBN: 1489902112 ISBN-13(EAN): 9781489902115
Издательство: Springer
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Цена: 28734.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Proceedings of the Fifteenth Washington International Spring Symposium held at The George Washington University, Washington, D.C., May 15-17, 1995

Neuroglia in Neurodegenerative Diseases

Автор: Verkhratsky Alexei, Ho Margaret S., Zorec Robert
Название: Neuroglia in Neurodegenerative Diseases
ISBN: 9811399158 ISBN-13(EAN): 9789811399152
Издательство: Springer
Рейтинг:
Цена: 23757.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book provides a comprehensive overview of the role of neuroglia in neurodegenerative diseases. In addition, to highlight the function of neuroglia in different types of neurodegenerative disease, it also discusses their mechanisms and effects on protecting or damaging neurons.

Neurodegenerative Diseases

Автор: Philip Beart; Michael Robinson; Marcus Rattray; Ni
Название: Neurodegenerative Diseases
ISBN: 3319860992 ISBN-13(EAN): 9783319860992
Издательство: Springer
Рейтинг:
Цена: 39130.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Provides a timely overview of critical advances in molecular and cellular neurobiology, covers key methodologies driving progress, and highlights key future directions for research on neuronal injury and neurodegeneration relevant to neuronal brain pathologies.

Neurochemical Aspects of Neurotraumatic and Neurodegenerative Diseases

Автор: Akhlaq A. Farooqui
Название: Neurochemical Aspects of Neurotraumatic and Neurodegenerative Diseases
ISBN: 1489982566 ISBN-13(EAN): 9781489982568
Издательство: Springer
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Цена: 28732.00 р.
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Описание: Neurodegenerative diseases are characterized by chronic and progressive loss of neurons in discrete areas of the brain. This book presents cutting-edge, comprehensive information on the molecular aspects of acute neural trauma and neurodegenerative diseases.

Metabolic And Bioenergetic Drivers Of Neurodegenerative Disease: Neurodegenerative Disease Research And Commonalities With Metabolic Diseases,154

Автор: Soderbom, Grazyna
Название: Metabolic And Bioenergetic Drivers Of Neurodegenerative Disease: Neurodegenerative Disease Research And Commonalities With Metabolic Diseases,154
ISBN: 0128200766 ISBN-13(EAN): 9780128200766
Издательство: Elsevier Science
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Цена: 26107.00 р.
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Описание:

Metabolic Drivers and Bioenergetic Components of Neurodegenerative Disease summarizes recent developments in intervention trials in neurodegenerative diseases, particularly Alzheimer's and Parkinson's, as well as increasing evidence for the overlap between drivers of metabolic and neurodegenerative disease that impact mitochondrial function and bioenergetics, and subsequently cellular function and pathophysiology. Topics covered include Brain Glucose and Ketone Utilization in Brain Ageing and Neurodegenerative Diseases; the Mitochondrial Hypothesis: Dysfunction, Bioenergetic Defects, and the Metabolic Link to Alzheimer's Disease; the Metabolic Impact on Neuroinflammation and Microglial Modulation in Neurodegenerative Diseases, the Impact of Circadian and Diurnal Rhythms on Cellular Metabolic Function and Neurodegenerative Diseases, and much more.

  • Summarizes the current status of and future research in Alzheimer's and Parkinson's diseases
  • Reviews the impact of the metabolic hypothesis on underlying mechanisms of neurodegenerative diseases.
Turmeric and curcumin for neurodegenerative diseases

Автор: Obulesu, Magisetty (regional Agricultural Research Station, Acharya N.g. Ranga Agricultural University, Tirupati, India)
Название: Turmeric and curcumin for neurodegenerative diseases
ISBN: 0128224487 ISBN-13(EAN): 9780128224489
Издательство: Elsevier Science
Рейтинг:
Цена: 19370.00 р.
Наличие на складе: Поставка под заказ.

Описание: Discover new places with fully updated road atlases from Collins. Full colour map of Ireland at 9 miles to 1 inch (1:570,240), with clear, detailed road network and counties and new administrative areas shown in colour. This double-sided map covers the whole of Ireland, and is ideal for reference or route planning.

RNA Metabolism in Neurodegenerative Diseases

Автор: Rita Sattler; Christopher J. Donnelly
Название: RNA Metabolism in Neurodegenerative Diseases
ISBN: 3030078329 ISBN-13(EAN): 9783030078324
Издательство: Springer
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Цена: 13974.00 р.
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Описание: It has become evident over the last years that abnormalities in RNA processing play a fundamental part in the pathogenesis of neurodegenerative diseases. Cellular viability depends on proper regulation of RNA metabolism and subsequent protein synthesis, which requires the interplay of many processes including transcription, pre--?mRNA splicing, mRNA editing as well as mRNA stability, transport and translation. Dysfunction in any of these processes, often caused by mutations in the coding and non--? coding RNAs, can be very destructive to the cellular environment and consequently impair neural viability. The result of this RNA toxicity can lead to a toxic gain of function or a loss of function, depending on the nature of the mutation. For example, in repeat expansion disorders, such as the newly discovered hexanucleotide repeat expansion in theC9orf72 gene found in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), a toxic gain of function leads to the formation of RNA foci and the sequestration of RNA binding proteins (RBPs). This in return leads to a loss of function of those RBPs, which is hypothesized to play a significant part in the disease progression of ALS and FTD. Other toxicities arising from repeat expansions are the formation of RNA foci, bi--?directional transcription and production of repeat associated non--?ATG (RAN) translation products.This book will touch upon most of these disease mechanisms triggered by aberrant RNA metabolism and will therefore provide a broad perspective of the role of RNA processing and its dysfunction in a variety of neurodegenerative disorders, including ALS, FTD, Alzheimer’s disease, Huntington’s disease, spinal muscular atrophy, myotonic dystrophy and ataxias. The proposed authors are leading scientists in the field and are expected to not only discuss their own work, but to be inclusive of historic as well as late breaking discoveries. The compiled chapters will therefore provide a unique collection of novel studies and hypotheses aimed to describe the consequences of altered RNA processing events and its newest molecular players and pathways.


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