This unique advanced textbook provides a clear and comprehensive overview of gene delivery, gene therapy and genetic pharmacology, with descriptions of the main gene transfer vectors and a set of selected therapeutic applications, along with safety considerations. The second edition features new groundbreaking material on genome editing using the recently discovered CRISPR/Cas9 system and on cancer immunotherapy by CAR-T cells. It also presents the historical milestone of gene therapy application in the field of severe combined immunodeficiency, and other fields of gene therapy and molecular medicine.
The use of gene transfer is exponentially growing in the scientific and medical communities for day-to-day cell biology experiments and swift development of gene therapy, which is already revolutionizing medicine. In this advanced textbook, more than 30 leading scientists come together to explore these topics.
This educational introduction provides the background material needed to further explore the subject as well as relevant research literature. It is an invaluable resource to Master, PhD or MD students, post-doctoral scientists or medical doctors, as well as any scientist wishing to deliver a gene or synthetic nucleotide or develop a gene therapy strategy. The second edition's simple and synthetic content will be of value to any reader interested in the biological and medical revolution derived from the elucidation of the human genome.
Описание: Chapter 1. Introduction.- Chapter 2. Synthetic Strategies for the Generation of Molecularly Imprinted Polymers.- Chapter 3. Special Control by Molecular Imprinting Materials-zero-order Sustained Release, Enantioselective MIPs and Self-regulated Drug Delivery Microdevices.- Chapter 4. Water Compatible Molecularly Imprinted Polymers.- Chapter 5. Stimuli Responsive Imprinted DDS.- Chapter 6. MIP as Drug Delivery Systems for Dermal Delivery.- Chapter 7. MIP as Drug Delivery Systems of Anticancer Agents.- Chapter 8. MIP as Dug Delivery Systems of Ophthalmic Drugs.- Chapter 9. MIP as Drug Delivery Systems for Special Application.- Chapter 10. Outlook.
Автор: Mart?n-Esteban Название: Molecularly Imprinted Polymers ISBN: 1071616315 ISBN-13(EAN): 9781071616314 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This detailed volume explores molecularly imprinted polymers (MIPs), which have attracted great interest both in fundamental research and for practical applications due to their selective molecular recognition capabilities, extraordinary stability, and ease of preparation.
Автор: Bo Mattiasson; Lei Ye Название: Molecularly Imprinted Polymers in Biotechnology ISBN: 3319371487 ISBN-13(EAN): 9783319371481 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Controlled radical polymerization techniques for molecular imprinting.- From bulk polymers to nanoparticles.- Post-imprinting and in-cavity functionalization.- Characterization of MIPs (affinity, selectivity, site heterogeneity...).- Theoretical aspects and computer modelling.- MIPs in aqueous environments, by Bin Lu.- MIPs for binding macromolecules.- Solid phase extraction.- Sensors.- MIPs for catalysis and synthesis.- Wastewater treatment.- MIPs as tools for bioassays, biotransformation and drug delivery.
Автор: Bo Mattiasson; Lei Ye Название: Molecularly Imprinted Polymers in Biotechnology ISBN: 3319207288 ISBN-13(EAN): 9783319207285 Издательство: Springer Рейтинг: Цена: 32652.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Controlled radical polymerization techniques for molecular imprinting.- From bulk polymers to nanoparticles.- Post-imprinting and in-cavity functionalization.- Characterization of MIPs (affinity, selectivity, site heterogeneity...).- Theoretical aspects and computer modelling.- MIPs in aqueous environments, by Bin Lu.- MIPs for binding macromolecules.- Solid phase extraction.- Sensors.- MIPs for catalysis and synthesis.- Wastewater treatment.- MIPs as tools for bioassays, biotransformation and drug delivery.
Автор: Martнn-Esteban Antonio Название: Molecularly Imprinted Polymers: Methods and Protocols ISBN: 1071616285 ISBN-13(EAN): 9781071616284 Издательство: Springer Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This detailed volume explores molecularly imprinted polymers (MIPs), which have attracted great interest both in fundamental research and for practical applications due to their selective molecular recognition capabilities, extraordinary stability, and ease of preparation.
Описание: This book describes the various approaches for developing novel drug delivery systems and the criteria for selection of drugs and polymers for the development of nanotechnology and targeted drug delivery systems. It also covers concepts, events and biological processes involved in drug targeting, tumour targeting and brain specific delivery. The major focus is to describe innovative approaches, types, formulation techniques, technologies, applications and evaluation of certain novel drug delivery systems such as liposomes, nanoparticles, microcapsules or microspheres, monoclonal antibodies, niosomes, aquasomes, phytosomes, and electrosomes.
The book encapsulated the change through intense analysis, new technologies, innovative evaluation of carriers and an array of practical approaches for pulmonary drug and nucleic acid based therapeutic delivery system, which will be handy for budding scientist and professional as well. Innovative techniques for drug delivery systems, applications of old theories with distinct reevaluation and well explained diagrams are the major part of this book.
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