Vaccine Design: Methods and Protocols, Vol. 1. Vaccines for Human Diseases, Thomas Sunil
Автор: Reich Jennifer A. Название: Calling the Shots: Why Parents Reject Vaccines ISBN: 1479874833 ISBN-13(EAN): 9781479874835 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 3762.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Winner, 2018 Donald W. Light Award for Applied Medical Sociology, American Sociological Association Medical Sociology Section Winner, 2018 Distinguished Scholarship Award presented by the Pacific Sociology Association Honorable Mention, 2017 ESS Mirra Komarovsky Book Award presented by the Eastern Sociological Society Outstanding Book Award for the Section on Altruism, Morality, and Social Solidarity presented by the American Sociological Association A rich, multi-faceted examination into the attitudes and beliefs of parents who choose not to immunize their children The measles outbreak at Disneyland in December 2014 spread to a half-dozen U.S. states and sickened 147 people. It is just one recent incident that the medical community blames on the nation’s falling vaccination rates. Still, many parents continue to claim that the risks that vaccines pose to their children are far greater than their benefits. Given the research and the unanimity of opinion within the medical community, many ask how such parents—who are most likely to be white, college educated, and with a family income over $75,000—could hold such beliefs.For over a decade, Jennifer Reich has been studying the phenomenon of vaccine refusal from the perspectives of parents who distrust vaccines and the corporations that make them, as well as the health care providers and policy makers who see them as essential to ensuring community health. Reich reveals how parents who opt out of vaccinations see their decision: what they fear, what they hope to control, and what they believe is in their child’s best interest. Based on interviews with parents who fully reject vaccines as well as those who believe in “slow vax,” or altering the number of and time between vaccinations, the author provides a fascinating account of these parents’ points of view. Placing these stories in dialogue with those of pediatricians who see the devastation that can be caused by vaccine-preventable diseases and the policy makers who aim to create healthy communities, Calling the Shots offers a unique opportunity to understand the points of disagreement on what is best for children, communities, and public health, and the ways in which we can bridge these differences.
Автор: Rees, Anthony Robert (founder Of Rees Consulting Ab, Stockholm, Sweden) Название: New history of vaccines for infectious diseases ISBN: 0128127546 ISBN-13(EAN): 9780128127544 Издательство: Elsevier Science Рейтинг: Цена: 13136.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A journey into ones mind is an exploration of the universe itself. A schizophrenic galaxy is a reality we live in. My thoughts led me into a walk down the electric roads in my mind, it was the winter that kept our love warm, Elysian fields of our extraterrestrial love. I hold you closer near the Arc de Triomphe where you justify the essence of a French kiss. We swift down Victor Hugo as my collar dances with your hair. We lay dazzled in Sainte-Chapelle screaming for your music, mesmerized by immortal trees, by weak leaves. Just like the soul you rescued, an infinite soul. A journey into ones mind is an exploration of our souls
Автор: Sara Cohen; Avigdor Shafferman Название: Novel Strategies in the Design and Production of Vaccines ISBN: 0306452111 ISBN-13(EAN): 9780306452116 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the 39th OHOLO Conference held in Eilat, Israel, May 7-11, 1995.
Автор: Sara Cohen; Avigdor Shafferman Название: Novel Strategies in the Design and Production of Vaccines ISBN: 148991384X ISBN-13(EAN): 9781489913845 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the 39th OHOLO Conference held in Eilat, Israel, May 7-11, 1995.
Автор: Dushyant Varshney; Manmohan Singh Название: Lyophilized Biologics and Vaccines ISBN: 1493955683 ISBN-13(EAN): 9781493955688 Издательство: Springer Рейтинг: Цена: 16070.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides a detailed account of the most recent developments, challenges and solutions to seamlessly advance and launch a lyophilized biologics or vaccine product, based on diverse modalities, ranging from antibodies (e.g., monoclonal, fused), complex biologics (e.g., antibody drug conjugate, PEGylated proteins), and vaccines (e.g., recombinant-protein based). The authors adeptly guide the reader through all crucial aspects, from biophysical and chemical stability considerations of proteins, analytical methods, advances in controlled ice nucleation and quality-by-design approaches, alternate drying technology, to latest regulatory, packaging and technology transfer considerations to develop a stable, safe and effective therapeutic protein, vaccine and biotechnology products. Lyophilized Biologics and Vaccines: Modality-Based Approaches is composed of four sections with a total of 17 chapters. It serves as a reference to all critical assessments and steps from early pre-formulation stages to product launch: * Provides recent understanding of heterogeneity of protein environment and selection of appropriate buffer for stabilization of lyophilized formulations * Details the latest developments in instrumental analysis and controlled ice nucleation technology * Explains in-depth lyophilized (or dehydrated) formulation strategies considering diverse modalities of biologics and vaccines, including plasmid DNA and lipid-based therapeutics * Details an exhaustive update on quality-by-design and process analytical technology approaches, illustrated superbly by case studies and FDA perspective * Provides the latest detailed account of alternate drying technologies including spray drying, bulk freeze-drying and crystallization, supported exceptionally by case studies * Provides a step-by-step guide through critical considerations during process scale-up, technology transfer, packaging and drug delivery device selection, for a successful lyophilization process validation, regulatory submission and product launch Chapters are written by one or more world-renowned leading authorities from academia, industry or regulatory agencies, whose expertise cover lyophilization of the diverse modalities of biopharmaceuticals. Their contributions are based on the exhaustive review of literature coupled with excellent hands-on experiences in laboratory or GMP setup, making this an exceptional guide to all stages of lyophilized or dehydrated product development.
Автор: Almeida de Sousa Название: DNA Vaccines: Methods and Protocols ISBN: 1071608711 ISBN-13(EAN): 9781071608715 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume details practical procedures on the latest DNA vaccine technology. Chapters guide readers through methods and protocols on DNA vaccine design, the adjuvant influence, production and purification methodologies, delivery systems, and approaches of the influence of DNA vaccines in the immunological response performance and in the cancer immunotherapy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, DNA Vaccines: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Автор: Bagnoli Fabio, Rappuoli Rino Название: Advanced Vaccine Research: Methods for the Decade of Vaccines ISBN: 1910190039 ISBN-13(EAN): 9781910190036 Издательство: Неизвестно Рейтинг: Цена: 45980.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Timo Vesikari; Pierre Van Damme Название: Pediatric Vaccines and Vaccinations ISBN: 3319867423 ISBN-13(EAN): 9783319867427 Издательство: Springer Рейтинг: Цена: 11179.00 р. Наличие на складе: Поставка под заказ.
Описание: This graduate textbook serves as a highly readable guide on vaccines and vaccination in infants, children and adolescents from an European perspective. The first part of the book is dedicated to childhood and adolescent vaccine schedules, maternal and neonatal immunization and safety of vaccines.
Автор: Kramps Thomas, Elbers Knut Название: RNA Vaccines: Methods and Protocols ISBN: 1493982141 ISBN-13(EAN): 9781493982141 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
1. Introduction to RNA Vaccines
Thomas Kramps and Knut Elbers
Part I: Self-replicating RNA Vectors
2. Self-replicating RNA
Birke A. Tews and Gregor Meyers
3. Self-replicating RNA Vaccine Delivery to Dendritic Cells
Thomas Dйmoulins, Pavlos C. Englezou, Panagiota Milona, Nicolas Ruggli, Nicola Tirelli, Chantal Pichon, Cйdric Sapet, Thomas Ebensen, Carlos A. Guzmбn, and Kenneth C. McCullough
4. Plant Expression of Trans-encapsidated Viral Nanoparticle Vaccines with Animal RNA Replicons
Yiyang Zhou, Alison A. McCormick, and Christopher M. Kearney
Part II: Non-replicating mRNA Vectors
5. RNActive(R) Technology: Generation and Testing of Stable and Immunogenic mRNA Vaccines
Susanne Rauch, Johannes Lutz, Aleksandra Kowalczyk, Thomas Schlake, and Regina Heidenreich
6. Nucleoside Modified mRNA Vaccines for Infectious Diseases
Norbert Pardi and Drew Weissman
7. Generation and Evaluation of Prophylactic mRNA Vaccines against Allergy
Richard Weiss, Sandra Scheiblhofer, and Josef Thalhamer
Part III: Adjuvantation and Delivery
8. Measuring the Adjuvant Activity of RNA Vaccines
Norbert Pardi and Drew Weissman
9. Generation of Immunostimulating 130 nm Protamine-RNA Nanoparticles
Marina Tusup and Steve Pascolo
10. Electroporation of mRNA as Universal Technology Platform to Transfect a Variety of Primary Cells with Antigens and Functional Proteins
Kerstin F. Gerer, Stefanie Hoyer, Jan Dцrrie, and Niels Schaft
11. Adjuvant-Enhanced mRNA Vaccines
Lukasz Bialkowski, Kevin Van der Jeught, Dries Renmans, Alexia van Weijnen, Carlo Heirman, Marleen Keyaerts, Karine Breckpot, and Kris Thielemans
12. Enhanced Delivery of DNA or RNA Vaccines by Electroporation
Kate E. Broderick and Laurent M. Humeau
Part IV: Preclinical and Clinical Development
13. The European Regulatory Environment of RNA-Based Vaccines
Thomas Hinz, Kajo Kallen, Cedrik M. Britten, Bruno Flamion, Ulrich Granzer, Axel Hoos, Christoph Huber, Samir Khleif, Sebastian Kreiter, Hans-Georg Rammensee, Ugur Sahin, Harpreet Singh-Jasuja, Цzlem Tьreci, and Ulrich Kalinke
14. Discovery and Subtyping of Neo-Epitope Specific T-cell Responses for Cancer Immunotherapy: Addressing the Mutanome
Mustafa Diken, Mathias Vormehr, Christian Grunwitz, Sebastian Kreiter, Цzlem Tьreci, and Ugur Sahin
15. Considerations for Producing mRNA Vaccines for Clinical Trials
Andreas Schmid
16. Nonclinical Safety Testing of RNA Vaccines
Gundel Hager
17. Immunotherapy of Uveal Melanoma: Vaccination Against Cancer
Mirko Kummer and Beatrice Schuler-Thurner
Автор: Kalkum Markus, Semis Margarita Название: Vaccines for Invasive Fungal Infections: Methods and Protocols ISBN: 1493983857 ISBN-13(EAN): 9781493983858 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This detailed volume focuses on the development of mycosis vaccines via the most common etiological agents of mycoses, such as Aspergillus and Candida species, followed by Cryptococcus, dimorphic fungi, and members of Mucoraceae family of fungi.
Автор: Ferran Maureen C., Skuse Gary R. Название: Recombinant Virus Vaccines: Methods and Protocols ISBN: 1493983237 ISBN-13(EAN): 9781493983230 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Preface... Table of Contents... Contributing Authors...
Part I Double-Stranded DNA Viruses
1. Development of Novel Vaccines Against Infectious Diseases Based on Chimpanzee Adenoviral Vector Chao Zhang, Yudan Chi, and Dongming Zhou
2. Development of Recombinant Canarypox Viruses Expressing Immunogens Dйbora Garanzini, Marнa Paula Del Mйdico-Zajac, and Gabriela Calamante
3. Fowl Adenovirus-Based Vaccine Platform Juan C. Corredor, Yanlong Pei, and Йva Nagy
4. Development of Recombinant HSV-Based Vaccine Vectors Richard Voellmy and David Bloom
5. Generating Recombinant Pseudorabies Virus for Use as a Vaccine Platform Feifei Tan, Xiangdong Li, and Kegong Tian
6. Generation and Production of Modified Vaccinia Virus Ankara (MVA) as a Vaccine Vector Vincent Pavot, Sarah Sebastian, Alison V. Turner, Jake Matthews, and Sarah C. Gilbert
7. Poxvirus Safety Analysis in the Pregnant Mouse Model, Vaccinia and Raccoonpox Viruses Rachel L. Roper
Part II Negative Sense Single-Stranded RNA viruses
8. Development of Recombinant Arenavirus-Based Vaccines Luis Martнnez-Sobrido and Juan Carlos de la Torre
9. Development of Recombinant Measles Virus-Based Vaccines Michael D. Mьhlebach and Stefan Hutzler
10. Recombinant Tri-Segmented Pichinde Virus as a Novel Live Viral Vaccine Platform Rekha Dhanwani, Hinh Ly, and Yuying Liang
11. Human Rhinovirus-A1 as an Expression Vector Khamis Tomusange, Danushka Wijesundara, Eric James Gowans, and Branka Grubor-Bauk
12. Generating Recombinant Vesicular Stomatitis Viruses for Use as Vaccine Platforms John B. Ruedas and John H. Connor
Part III Positive Sense Single-Stranded RNA viruses
13. Alphavirus-Based Vaccines Kenneth Lundstrom
Part IV Bacteriophage
14. Display of HIV-1 Envelope Protein on Lambda Phage Scaffold as a Vaccine Platform Jonelle L. Mattiacio, Matt Brewer, and Stephen Dewhurst
15. Bacteriophage T4 as a Nanoparticle Platform to Display and Deliver Pathogen Antigens: Construction of an Effective Anthrax Vaccine Pan Tao, Qin Li, Sathish Shivachandra, and Venigalla B. Rao
Описание: Genetically Engineered Plants as a Source of Vaccines Against Wide Spread Diseases: An Integrated View provides an integrated outlook of the disciplines involved in the development of plant-based vaccines as well as an updated compilation of the successful developments in the field. The volume covers immunological aspects of mucosal vaccine design, molecular approaches to attain high levels of the recombinant antigens, the rationale of using bioreactor to expand plant biomass, and pharmaceutical technology approaches that have been applied to the development of plant-based vaccine formulations. Practical figures and tables are presented to facilitate reading and identification of key points. Perspectives for this field are also discussed. Written by authorities in the field, Genetically Engineered Plants as a Source of Vaccines Against Wide Spread Diseases: An Integrated View is a comprehensive resource for researchers and students interested in plant genetics and breeding, immunology, and genetic engineering.
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