The Role of Microbes in Autoimmune Diseases: New Mechanisms of Microbial Initiation of Autoimmunity, Alkhatib Ahed J.
Автор: Weber Chloe Название: Autoimmunity and Autoimmune Diseases ISBN: 1632426870 ISBN-13(EAN): 9781632426871 Издательство: Неизвестно Рейтинг: Цена: 23335.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: C. Jane Welsh; Mary Meagher; Esther Sternberg Название: Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity ISBN: 0387314113 ISBN-13(EAN): 9780387314112 Издательство: Springer Рейтинг: Цена: 22203.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides a lucid summary of behavioral, neural and endocrine regulation of immune responses and of the effects of immune system activity on neural and endocrine functions and behavior. The underlying premise is that the brain and immune system represent a single, integrated system of defense.
Автор: Fredda Ginsberg-Fellner; Robert C. McEvoy Название: Autoimmunity and the Pathogenesis of Diabetes ISBN: 1461279208 ISBN-13(EAN): 9781461279204 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Explains how immune system functions, namely, how individual cells of the immune system make the decision to respond or not to respond to foreign microbes and molecules, and how the critical molecules function to trigger the cellular reactions in an all-or-none manner. This book also explains why vaccines fail.
Автор: Tollefsbol, Trygve Название: The Epigenetics of Autoimmunity ISBN: 0128099127 ISBN-13(EAN): 9780128099124 Издательство: Elsevier Science Рейтинг: Цена: 23917.00 р. Наличие на складе: Поставка под заказ.
Описание: The Epigenetics of Autoimmunity covers a topic directly related to translational epigenetics. Via epigenetic mechanisms, a number of internal and external environmental risk factors, including smoking, nutrition, viral infection and the exposure to chemicals, could exert their influence on the pathogenesis of autoimmune diseases. Such factors could impact the epigenetic mechanisms, which, in turn, build relationship with the regulation of gene expression, and eventually triggering immunologic events that result in instability of immune system. Since epigenetic aberrations are known to play a key role in a long list of human diseases, the translational significance of autoimmunity epigenetics is very high. . To bridge the gap between environmental and genetic factors, over the past few years, great progress has been made in identifying detailed epigenetic mechanisms for autoimmune diseases. Furthermore, with rapid advances in technological development, high-throughput screening approaches and other novel technologies support the systematic investigations and facilitate the epigenetic identification. This book covers autoimmunity epigenetics from a disease-oriented perspective and several chapters are presented that provide advances in wide-spread disorders or diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), multiple sclerosis (MS), type 1 diabetes (T1DM), systemic sclerosis (SSc), primary Sj?gren's syndrome (pSS) and autoimmune thyroid diseases (AITDs). . These emerging epigenetic studies provide new insights into autoimmune diseases, raising great expectations among researchers and clinicians. This seminal book on this topic comprehensively covers the most recent advances in this exciting and rapidly developing new science. They might reveal not only new clinical biomarkers for diagnosis and disease progression, but also novel targets for potential epigenetic therapeutic treatment.
Автор: C. Jane Welsh; Mary Meagher; Esther Sternberg Название: Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity ISBN: 1489997237 ISBN-13(EAN): 9781489997234 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides a lucid summary of behavioral, neural and endocrine regulation of immune responses and of the effects of immune system activity on neural and endocrine functions and behavior. The underlying premise is that the brain and immune system represent a single, integrated system of defense.
Описание: In a fully revised second edition, this comprehensive review of clinical and experimental aspects of IL-17 and IL-22 and the cells that produce them covers the latest scientific advances, with additional chapters on processes such as receptor family signaling.
Описание: In a fully revised second edition, this comprehensive review of clinical and experimental aspects of IL-17 and IL-22 and the cells that produce them covers the latest scientific advances, with additional chapters on processes such as receptor family signaling.
Автор: Rahmani Название: Pediatric Autoimmunity and Transplantation ISBN: 3030262790 ISBN-13(EAN): 9783030262792 Издательство: Springer Рейтинг: Цена: 11878.00 р. Наличие на складе: Поставка под заказ.
Описание: Further, the volume examines other agents, a number of cells, receptors and signaling molecules, that are also involved in the regulation of T-cell activation and extends the concept of immune checkpoints to "molecules and cells that negatively regulate T-cell activation".
Автор: Moncef Zouali Название: Molecular Autoimmunity ISBN: 1461498945 ISBN-13(EAN): 9781461498940 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: - Preface -Contributors -Innate Immunity in Experimental Autoimmune Myocarditis -Toll-Like Receptor 9 and Autoimmunity -C-Reactive Protein as a Regulator of Autoimmune Disease -NKT Cells and Autoimmune Type 1 Diabetes -The Genetics of Human Autoimmune Diseases -Failure to Maintain T cell DNA Methylation and Chromatin Structure Contributes to Human Lupus -Complement Components C4A and C4B in Human Lupus -Non-MHC Genetic Polymorphisms with Functional Importance for Human Myasthenia Gravis -Rheumatic Heart Disease: Molecular Basis of Autoimmune Reactions Leading to Valvular Lesions -Autoimmunity Against Desmogleins in Pemphigus Vulgaris -The Molecular Basis of Celiac Disease -Intrathymic Expression of Neuromuscular Acetylcholine Receptors and the Immunopathogenesis of Myasthenia Gravis -Autoantiboties and Nephritis: Different Roads May Lead to Rome -Estrogen, Interferon-gamma, and Lupus -Extent of Regulatory T cell Influence on Major Histocompatibility Complex Class II Gene Control of Susceptibility in Murine Autoimmune Thyroiditis -The Role of Autoimmunity in Multiple Sclerosis -Crippled B Lymphocyte Signaling Checkpoints in Systemic Autoimmunity -Disrupted T cell Receptor Signaling Pathways in Systemic Autoimmunity -Immune cell Signaling and Gene Transcription in Human Systemic Lupus Erythematosus -Accumulation of Self-Antigens in Systemic Lupus Erythematosus -B Lymphocyte Depletion Therapy in Autoimmune Disorders: Chasing Trojan Horse? -B Lymphocyte Stimulator (BLyS) and Autoimmune Rheumatic Diseases -Control and Induction of Autoimmunity by Cytokine and Anti-Cytokine Treatments -Hematopoietic Stem Cell Transplantation for the Treatment of Severe Autoimmune Diseases -Molecular Mimicry in Autoimmune Uveitis: From Pathogenesis to Therapy -Molecular Pathogenesis of the Antiphospholipid Syndrome: Towards Novel Therapeutic Targets -A Novel Approach to the Prevention of Atherosclerosis -Antigen-SpecificRegulation of Autoimmunity -Index
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