Emerging Concepts Targeting Immune Checkpoints in Cancer and Autoimmunity, Akihiko Yoshimura
Автор: Andras Perl Название: Autoimmunity ISBN: 149395637X ISBN-13(EAN): 9781493956371 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Continued refinement of wide-spread access to transgenic technology has allowed for new animal models have been developed that exhibit features of autoimmune disease have been developed that exhibit features of autoimmune disease.
Описание: Further, the volume examines other agents, a number of cells, receptors and signaling molecules, that are also involved in the regulation of T-cell activation and extends the concept of immune checkpoints to "molecules and cells that negatively regulate T-cell activation".
Автор: Tollefsbol, Trygve Название: The Epigenetics of Autoimmunity ISBN: 0128099127 ISBN-13(EAN): 9780128099124 Издательство: Elsevier Science Рейтинг: Цена: 23917.00 р. Наличие на складе: Поставка под заказ.
Описание: The Epigenetics of Autoimmunity covers a topic directly related to translational epigenetics. Via epigenetic mechanisms, a number of internal and external environmental risk factors, including smoking, nutrition, viral infection and the exposure to chemicals, could exert their influence on the pathogenesis of autoimmune diseases. Such factors could impact the epigenetic mechanisms, which, in turn, build relationship with the regulation of gene expression, and eventually triggering immunologic events that result in instability of immune system. Since epigenetic aberrations are known to play a key role in a long list of human diseases, the translational significance of autoimmunity epigenetics is very high. . To bridge the gap between environmental and genetic factors, over the past few years, great progress has been made in identifying detailed epigenetic mechanisms for autoimmune diseases. Furthermore, with rapid advances in technological development, high-throughput screening approaches and other novel technologies support the systematic investigations and facilitate the epigenetic identification. This book covers autoimmunity epigenetics from a disease-oriented perspective and several chapters are presented that provide advances in wide-spread disorders or diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), multiple sclerosis (MS), type 1 diabetes (T1DM), systemic sclerosis (SSc), primary Sj?gren's syndrome (pSS) and autoimmune thyroid diseases (AITDs). . These emerging epigenetic studies provide new insights into autoimmune diseases, raising great expectations among researchers and clinicians. This seminal book on this topic comprehensively covers the most recent advances in this exciting and rapidly developing new science. They might reveal not only new clinical biomarkers for diagnosis and disease progression, but also novel targets for potential epigenetic therapeutic treatment.
Описание: This book systematically reviews the most important findings on cancer immune checkpoints, sharing essential insights into this rapidly evolving yet largely unexplored research topic.
Автор: Farzaneh Rahmani; Nima Rezaei Название: Pediatric Autoimmunity and Transplantation ISBN: 3030262820 ISBN-13(EAN): 9783030262822 Издательство: Springer Рейтинг: Цена: 11878.00 р. Наличие на складе: Поставка под заказ.
Описание: Theologies on the Move examines how the experiences of migration and pilgrimage that are created as a result of the pressures of neoliberal capitalism shape theological and religious traditions. Based on these insights, the contributors examine what difference religion can make in a world dominated by the interests of the few rather than the many.
Автор: Andreas Radbruch; Peter E. Lipsky Название: Current Concepts in Autoimmunity and Chronic Inflammation ISBN: 364206745X ISBN-13(EAN): 9783642067457 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In addition, there are in?uences that are extrinsic to potentially auto-reactive lymphocytes, including the function of regulatory cells, d- ferentiation state of antigen-presenting cells, availability of self-antigen, the cytokine and chemokine milieu, as well as the traf?cking patterns involved in generating productive immune interactions.
Автор: A.G. Dalgleish; A. Albertini; Rodolfo Paoletti Название: The Impact of Biotechnology on Autoimmunity ISBN: 0792327241 ISBN-13(EAN): 9780792327240 Издательство: Springer Рейтинг: Цена: 27951.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The association with infectious diseases and autoimmunity is comprehensively covered by David Isenberg who reviews major issues, such as the association of autoantibodies appearing after infectious disease and antibacterial antibodies associated with autoimmune disease.
Автор: A. Pinchera Название: Thyroid Autoimmunity ISBN: 1461282586 ISBN-13(EAN): 9781461282587 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In 1956, three groups independently reported evidence that some thyroid disease appearing spontaneously in humans or experimentally induced in animals are related to autoimmune processes.
Автор: A.G. Dalgleish; A. Albertini; Rodolfo Paoletti Название: The Impact of Biotechnology on Autoimmunity ISBN: 9401044848 ISBN-13(EAN): 9789401044844 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The association with infectious diseases and autoimmunity is comprehensively covered by David Isenberg who reviews major issues, such as the association of autoantibodies appearing after infectious disease and antibacterial antibodies associated with autoimmune disease.
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