Aging Mechanisms II: Longevity, Metabolism, and Brain Aging, Mori Nozomu
Автор: Moskalev, Alexey Название: Epigenetics of Aging and Longevity ISBN: 0128110600 ISBN-13(EAN): 9780128110607 Издательство: Elsevier Science Рейтинг: Цена: 19875.00 р. Наличие на складе: Поставка под заказ.
Описание:
Epigenetics of Aging and Longevity provides an in-depth analysis of the epigenetic nature of aging and the role of epigenetic factors in mediating the link between early-life experiences and life-course health and aging. Chapters from leading international contributors explore the effect of adverse conditions in early-life that may result in disrupted epigenetic pathways, as well as the potential to correct these disrupted pathways via targeted therapeutic interventions. Intergenerational epigenetic inheritance, epigenetic drug discovery, and the role of epigenetic mechanisms in regulating specific age-associated illnesses--including cancer and cardiovascular, metabolic, and neurodegenerative diseases--are explored in detail.
This book will help researchers in genomic medicine, epigenetics, and biogerontology better understand the epigenetic determinants of aging and longevity, and ultimately aid in developing therapeutics to extend the human life-span and treat age-related disease.
Автор: Bucala Richard & Lee Patty J Название: Aging Lungs, The: Mechanisms And Clinical Sequelae ISBN: 9814635006 ISBN-13(EAN): 9789814635004 Издательство: World Scientific Publishing Рейтинг: Цена: 26136.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume provides a comprehensive and multi-disciplinary overview of the aging lung, written by the main researchers in the field. Current physiological, cellular and molecular understanding of how the lungs age and the relationship to age-associated lung diseases will be presented.
Автор: Christian Behl; Christine Ziegler Название: Cell Aging: Molecular Mechanisms and Implications for Disease ISBN: 3642451780 ISBN-13(EAN): 9783642451782 Издательство: Springer Рейтинг: Цена: 9141.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Aging represents a physiological and per se non-pathological and multifactorial process involving a set of key genes and mechanisms being triggered by different endogenous and exogenous factors.
Автор: Nektarios Tavernarakis Название: Protein Metabolism and Homeostasis in Aging ISBN: 1489979395 ISBN-13(EAN): 9781489979391 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book examines the role of protein metabolism and homeostasis in aging. It offers an overview of the current knowledge in the area, including protein synthesis, accuracy and repair, post-translational modifications, and degradation and turnover.
Автор: Konrad Beyreuther; Gotthard Schettler Название: Molecular Mechanisms of Aging ISBN: 354052732X ISBN-13(EAN): 9783540527329 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A high-level text on the molecular and genetic aspects of human ageing with reference to cognitive functions and age-related diseases.
Автор: Carolyn M. Ecelbarger, Dharmendra Kumar Chaudhary, Hwal Lee, Swasti Tiwari Название: Molecular Mechanisms of Body Water Homeostasis ISBN: 1615047328 ISBN-13(EAN): 9781615047321 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 5016.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Discusses our intimate relationship with and dependence on water, how the body regulates its water levels, and various pathophysiological states associated with impairments in body water homeostasis. The human body consists of 70-80% water. Therefore, concise control of water homeostasis is essential to survival and involves coordination of several systems.
Описание: This book provides an overview of recent advances in the study of aging and aging related diseases, discussing the topics at individual, organ, tissue, cell, and molecular levels. It also presents studies on the biomarkers of aging and anti-aging interventions.Aging has been becoming a global health problem. However it was not possible to determine aging as we usually diagnose a disease because there are few biomarkers for age estimation. Since ancient times, people have been seeking anti-aging substances and methods for achieving immortality, while the scientific study of aging has only existed for 100 years. This book appeals to researchers both in institutes and in pharmaceutical companies interested in further studies in this field.
Описание: Maintaining good metabolic profile plays a significant role in improving the quality of life at aging. Widely recommended physical and psychological strategies include exercise, calorie restriction (such as healthy diet), anti-aging neuroprotective and anti-inflammation therapy. Most occurring risks at middle age range (45-65 years old) are obesity, insulin resistance, inflammation, alteration in the hypothalamus-hypophysis suprarenal axis activity, stress and hypertension that could increase the prevalence of metabolic syndrome. Metabolic syndrome increases with age, particularly for women. Significant associations were seen between imaging measures and cardiovascular risk factors at both baseline and 18-month follow-ups. Both baseline and longitudinal imaging analysis and correlations with neurocogntive tests as well as cardiovascular risk factors could provide distinct and confirmative perspectives relating to the pathophysiology of aging-related diseases such as dementia and diabetes. Significant baseline and longitudinal effects of age, smoking and neuropathological burdens such as amyloid, tau and glucose metabolism provide a complete imaging, neurocognitive and cardiovascular profile for better staging and differentiating different diseases. Together with accurate imaging guidance, early detection and treatment could be achieved with the ultimate goal of improving quality of life at middle age and extending longevity. The aim of this book is intended to provide both beginners and experts in biomedical imaging and health care a broad picture as well as new development in brain function and metabolism of aging using innovative neuroimaging techniques and advanced longitudinal /correlational analyses. Methods and data presented in this book with novel experimental designs and protocols, especially longitudinal investigation of multiple imaging metrics from microvascular, micro-structural to systematic functional, metabolic and neuropathological perspectives will help improving diagnosis and early prevention of common diseases at middle age such as metabolic syndrome and early dementia. Some promising prevention strategies such as arts therapy, aerobic exercise and calorie restriction will be introduced additionally with imaging evidence. Results presented will help improving diagnosis accuracy, staging, and determining phases and trajectories of disease progression with age, endothelial dysfunction and deficits in metabolic syndrome. This book will provide the current state-of-the-art and new frontiers of brain function and metabolic changes at age using multi-parametric functional, structural and molecular imaging techniques in detection, diagnosis and treatment. We will present some forefront and interesting multi-dimensional baseline and longitudinal imaging techniques to serve as a reference and resource book in neuroimaging application and research field. Several distinct detection and application perspectives, including cutting-edge imaging methods from baseline evaluations to longitudinal applications as well as multi-modal and multi-parametric quantifications will be described. The relatively new and advanced data and results together with interesting examples and application demonstrations could help facilitate the generalisation, interpretation and applications of these techniques to improve disease diagnosis, quality of life and treatment for metabolic syndrome and brain dysfunction.
Автор: Jacqueline L. Angel; Fernando Torres-Gil; Kyriakos Название: Aging, Health, and Longevity in the Mexican-Origin Population ISBN: 148999792X ISBN-13(EAN): 9781489997920 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Aging, Health, and Longevity in the Mexican-Origin Population creates a foundation for an interdisciplinary discussion of the trajectory of disability and long-term care for older people of Mexican-origin from a bi-national perspective.
Автор: Arthur V. Everitt; Suresh I. S. Rattan; David G. C Название: Calorie Restriction, Aging and Longevity ISBN: 9400791151 ISBN-13(EAN): 9789400791152 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Long-term reduction in calorie intake will delay the onset of age-related diseases such as heart disease, diabetes and cancer. This book provides the latest information on the beneficial effects of calorie restriction on health and life-span.
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru
