Автор: Jerzy Be?towski Название: Vascular Effects of Hydrogen Sulfide ISBN: 1493995278 ISBN-13(EAN): 9781493995271 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Поставка под заказ.
Описание: This book explores techniques for exploring hydrogen sulfide (H2S) and its effects on the vascular system through numerous experimental animal models and vascular preparations. Alterations of vascular H2S generation/signaling may be involved in the pathogenesis of systemic and pulmonary arterial hypertension, ischemic heart disease, ischemic stroke, preeclampsia, and erectile dysfunction, and H2S also serves as an attractive target for pharmacotherapy of cardiovascular diseases, as well as possible effects on cancer, wound healing, and diabetic retinopathy, among other pathologies. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Vascular Effects of Hydrogen Sulfide: Methods and Protocols is an ideal aid for scientists working to extend our knowledge in this valuable and wide-ranging field of study.
Автор: Thomas Dittmar; Kurt S. Z?nker Название: Cell Fusion in Health and Disease ISBN: 9400735715 ISBN-13(EAN): 9789400735712 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This 2-volume set covers the processes of cell fusion in health and disease, including fertilization, placentation, and cell fusion in cellular reprogramming and cancer vaccine development, and on the role of cell fusion in cancer development and progression.
Автор: Thomas Dittmar; Kurt S. Z?nker Название: Cell Fusion in Health and Disease ISBN: 9400735960 ISBN-13(EAN): 9789400735965 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In these volumes, leading experts present up-to-date overviews about cell fusion in physiological and patho-physiological processes. Volume 1 deals with Cell Fusion in Health, Volume 2 focuses on Cell Fusion in Disease.
Автор: Jensen Название: RNA Exosome ISBN: 1441978402 ISBN-13(EAN): 9781441978400 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Поставка под заказ.
Описание: Assembling work by prominent researchers in the field of RNA exosomes, this excellent introduction to the fascinating protein complex provides a comprehensive account of the proteins` many functions as well as a historical account of the field`s development.
Автор: Cheng Название: Molecular Mechanisms in Spermatogenesis ISBN: 0387799907 ISBN-13(EAN): 9780387799902 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Поставка под заказ.
Описание: Includes chapters on the development in the field of molecular mechanisms in spermatogenesis using genomic and proteomic approaches to study spermatogenesis, as well as different mechanisms and/or molecules including environmental toxicants and transcription factors that regulate and/or affect spermatogenesis.
Автор: Fallon, Padraic G. (Ed.) Название: Pathogen-Derived Immunomodulatory Molecules ISBN: 1441916008 ISBN-13(EAN): 9781441916006 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Examining the molecules that pathogens produce, this volume studies how those pathogens either regulate or usurp the functions of the immune system. In short, these chapters explore the use of pathogen-derived immune modulating molecules as a therapy.
Автор: June E. Ayling; M. Gopal Nair; Charles M. Baugh Название: Chemistry and Biology of Pteridines and Folates ISBN: 1461362873 ISBN-13(EAN): 9781461362876 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the Tenth International Symposium held in Orange Beach, Alabama, March 21-26, 1993
Автор: Zhu Yi-Chun Название: Advances in Hydrogen Sulfide Biology ISBN: 981160990X ISBN-13(EAN): 9789811609909 Издательство: Springer Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is intended for periodontal residents and practicing periodontists who wish to incorporate the principles of moderate sedation into daily practice. Comprehensive airway management and rescue skills are then documented in detail so that the patient may be properly managed in the event that the sedation progresses beyond the intended level.
Автор: Jerzy Be?towski Название: Vascular Effects of Hydrogen Sulfide ISBN: 1493995308 ISBN-13(EAN): 9781493995301 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Поставка под заказ.
Автор: Philip K. Moore; Matt Whiteman Название: Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide ISBN: 3319181432 ISBN-13(EAN): 9783319181431 Издательство: Springer Рейтинг: Цена: 41925.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book puts hydrogen sulfide in context with other gaseous mediators such as nitric oxide and carbon monoxide, reviews the available mechanisms for its biosynthesis and describes its physiological and pathophysiological roles in a wide variety of disease states. Hydrogen sulfide has recently been discovered to be a naturally occurring gaseous mediator in the body. Over a relatively short period of time this evanescent gas has been revealed to play key roles in a range of physiological processes including control of blood vessel caliber and hence blood pressure and in the regulation of nerve function both in the brain and the periphery. Disorders concerning the biosynthesis or activity of hydrogen sulfide may also predispose the body to disease states such as inflammation, cardiovascular and neurological disorders. Interest in this novel gas has been high in recent years and many research groups worldwide have described its individual biological effects. Moreover, medicinal chemists are beginning to synthesize novel organic molecules that release this gas at defined rates with a view to exploiting these new compounds for therapeutic benefit.
Автор: Hideo Kimura Название: Hydrogen Sulfide and its Therapeutic Applications ISBN: 370911974X ISBN-13(EAN): 9783709119747 Издательство: Springer Рейтинг: Цена: 16070.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The metabolism of sulfur especially by sulfurtransferases had been intensively studied in mid 1900’s. Three enzymes, cystathionine ?–synthase (CBS), cystathionine ?–lyase (CSE) and 3-mercaptopyruvate sulfurtransferase (3MST) were found to have the capacity to produce H2S in vitro. However, H2S was recognized simply as a by-product of the metabolic pathways or as a marker for evaluating the activity of enzymes rather than as a physiological active molecule. In the late 1980’s relatively high concentrations of sulfide were measured in the brain that led to the successive studies of identifying the physiological functions of H2S. Recently, the steady-state concentrations of H2S have been re-evaluated and found to be much less than that initially measured. However, despite these differences, such re-evaluations served to further confirm the existence of H2S in mammalian tissues. H2S is produced in almost every organ and plays various roles such as neuromodulation, vasodilation, insulin release, inflammation, angiogenesis and cytoprotection. The unregulated production of H2S and improper responses of target molecules are involved in the pathogenesis of various diseases. This book focuses on these topics as well as on the recent progress in the biology and the therapeutic development of this molecule.
Автор: Philip K. Moore; Matt Whiteman Название: Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide ISBN: 3319359096 ISBN-13(EAN): 9783319359090 Издательство: Springer Рейтинг: Цена: 41925.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book puts hydrogen sulfide in context with other gaseous mediators such as nitric oxide and carbon monoxide, reviews the available mechanisms for its biosynthesis and describes its physiological and pathophysiological roles in a wide variety of disease states. Hydrogen sulfide has recently been discovered to be a naturally occurring gaseous mediator in the body. Over a relatively short period of time this evanescent gas has been revealed to play key roles in a range of physiological processes including control of blood vessel caliber and hence blood pressure and in the regulation of nerve function both in the brain and the periphery. Disorders concerning the biosynthesis or activity of hydrogen sulfide may also predispose the body to disease states such as inflammation, cardiovascular and neurological disorders. Interest in this novel gas has been high in recent years and many research groups worldwide have described its individual biological effects. Moreover, medicinal chemists are beginning to synthesize novel organic molecules that release this gas at defined rates with a view to exploiting these new compounds for therapeutic benefit.
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