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Anticipatory Ethics and The Use of CRISPR in Humans, Nestor


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Цена: 18167.00р.
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Автор: Nestor
Название:  Anticipatory Ethics and The Use of CRISPR in Humans
ISBN: 9783030983673
Издательство: Springer
Классификация:

ISBN-10: 3030983676
Обложка/Формат: Hardback
Страницы: 145
Вес: 0.42 кг.
Дата издания: 04.06.2022
Язык: English
Издание: 1st ed. 2022
Иллюстрации: 12 illustrations, color; 1 illustrations, black and white; xix, 145 p. 13 illus., 12 illus. in color.
Размер: 235 x 155
Читательская аудитория: Professional & vocational
Основная тема: Biomedicine
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: The future of gene editing in humans will involve the use of CRISPR. How we think about the combination of the scientific, ethical, and moral aspects of this technology is paramount to the success or failure of CRISPR in humans. Unfortunately, the current scientific discussion around CRISPR in humans has left ethics trailing behind due to the rapid pace of innovation. New modes of ethics and stakeholder participation are needed to keep pace with rapid scientific advances and provide the necessary policy and ethical frameworks necessary to help CRISPR flourish as an important health care tool to treat human disease. This requires intense interdisciplinary collaboration and discussion between scientists and philosophers, policymakers and legal scholars, and the public. Dr. Michael W. Nestor (a neuroscientist who actively uses CRISPR in pre-clinical research) and Professor Richard Wilson (a philosopher who focuses on anticipatory ethics) set out to develop a new ethical approach considering the use of CRISPR in human targeted therapies. The field of anticipatory ethics is uniquely poised to tackle questions in fast-evolving technical areas where the pace of innovation outstrips traditional philosophical approaches. Furthermore, because of its “anticipatory” nature, this type of analysis provides the opportunity to look ahead and into the future concerning potential uses of CRISPR in humans, uses that are not currently possible. Nestor and Wilson collaborate both scientifically and philosophically in this book to forecast potential outcomes as the scientific and medical community goes beyond using CRISPR to correct genes that underlie diseases where a single gene is involved. Instead, Nestor and Wilson envision CRISPR in complex, multigenic disorders with a specific focus on the use of CRISPR to edit genes involved in mental traits like IQ or other cognitive characteristics. They argue that the use of CRISPR to modify genes that are potentially important for mental traits represents a particular category for special consideration from scientists, policymakers, the public, and other stakeholders. Nestor and Wilson explain why using CRISPR to alter mental states is very different from treating a disease like cancer by combining the latest scientific advancements with anticipatory ethics and philosophical phenomenology. Their analysis considers the role that mental states play in personhood and the lived experience-as genes that can change mental/cognitive attributes like IQ have wide-ranging effects on the lived experience in ways that are categorically different from other attributes. This book was written to set a non-exhaustive framework for shared understanding and discussion across disciplines and appeal to scientists and non-scientists alike. This appeal is made inclusively, inviting all stakeholders to engage in active dialogue about the appropriate context for using CRISPR and other gene-editing technologies in humans. It provides policy analysis and recommendations for assuring the most inclusive, equitable, and ethically sound use of CRISPR in humans, concerning its positive potential to treat mental conditions like depression, schizophrenia, Alzheimer’s disease, autism, and the potential to induce other cognitive enhancements.
Дополнительное описание: Chapter 1: Brief Introduction to CRISPR Cas 9.- Chapter 2: Introduction To Anticipatory Ethics.- Chapter 3: CRISPR, Phenomenology and Lived Experience.- Chapter 4: CRISPR and the Concept of Personhood.- Chapter 5: The use and access to CRISPR in historica



CRISPR Crops: The Future of Food Security

Автор: Ahmad Aftab, Khan Sultan Habibullah, Khan Zulqurnain
Название: CRISPR Crops: The Future of Food Security
ISBN: 9811571449 ISBN-13(EAN): 9789811571442
Издательство: Springer
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Цена: 25155.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book compiles the latest applications of the cutting-edge gene editing tool CRISPR/Cas in the area of crop improvement.

CRISPR Gene Editing

Автор: Yonglun Luo
Название: CRISPR Gene Editing
ISBN: 1493991698 ISBN-13(EAN): 9781493991693
Издательство: Springer
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Цена: 25155.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This detailed volume guides readers through strategic planning and user-friendly guidelines in order to select the most suitable CRISPR-Cas system and target sites with high activity and specificity. Methods covering CRISPR gRNA design, CRISPR delivery, CRISPR activity quantification (indel quantification), and examples of applying CRISPR gene editing in human pluripotent stem cells, primary cells, gene therapy, and genetic screening are included. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and invaluable, CRISPR Gene Editing: Methods and Protocols will assist undergraduates, graduates, and researchers with detailed guidelines and methods for the vitally important CRISPR gene editing field.
Chapter 3 is available open access under a CC BY 4.0 license via link.springer.com.
Crispr Crops: The Future of Food Security

Автор: Ahmad Aftab, Khan Sultan Habibullah, Khan Zulqurnain
Название: Crispr Crops: The Future of Food Security
ISBN: 9811571414 ISBN-13(EAN): 9789811571411
Издательство: Springer
Цена: 25155.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book compiles the latest applications of the cutting-edge gene editing tool CRISPR/Cas in the area of crop improvement.

Crispr Guide RNA Design: Methods and Protocols

Автор: Fulga Tudor A., Knapp David J. H. F., Ferry Quentin R. V.
Название: Crispr Guide RNA Design: Methods and Protocols
ISBN: 1071606867 ISBN-13(EAN): 9781071606865
Издательство: Springer
Цена: 18167.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Beginning with a section on computational design of target-specific guide RNAs, the book continues by covering chemical modifications to alter guide RNA stability, specificity, and efficiency, as well as to create inducible guide RNAs, append additional functional domains, and express guide RNAs in a conditional manner.

RNA Interference and CRISPR Technologies

Автор: Mouldy Sioud
Название: RNA Interference and CRISPR Technologies
ISBN: 1071602896 ISBN-13(EAN): 9781071602898
Издательство: Springer
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Цена: 23058.00 р.
Наличие на складе: Нет в наличии.

Описание: This volume explores the uses of RNAi and CRISPR interferences as a general method for inhibiting gene expression, with focus on their biological functions, design, chemical modifications, delivery, and preclinical/clinical applications. In addition to relevant backgrounds, the chapters in this book discuss simple and accurate protocols dealing with the latest advances in RNAi and CRISPR applications and look at how these methods differ from one another. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, RNA Interference and CRISPR Technologies: Technical Advances and New Therapeutic Opportunities is a valuable resource for any scientist, teachers, graduate student, postdoc, and clinician interested in this field. This book also benefits anyone in research and development in biotech and pharmaceutical companies who want to understand more about these technologies, and their applications in biology and medicine.

Precision Medicine, Crispr, and Genome Engineering: Moving from Association to Biology and Therapeutics

Автор: Tsang Stephen H.
Название: Precision Medicine, Crispr, and Genome Engineering: Moving from Association to Biology and Therapeutics
ISBN: 3319876678 ISBN-13(EAN): 9783319876672
Издательство: Springer
Рейтинг:
Цена: 27950.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book presents descriptive overviews of gene editing strategies across multiple species while also offering in-depth insight on complex cases of application in the field of tissue engineering and regenerative medicine. Chapters feature contributions from leaders in stem cell therapy and biology, providing a comprehensive view of the application of gene therapy in numerous fields with an emphasis on ophthalmology, stem cells, and agriculture. The book also highlights recent major technological advances, including ZFN, TALEN, and CRISPR. Precision Medicine, CRISPR, and Genome Engineering is part of the highly successful Advances in Experimental Medicine and Biology series. It is an indispensable resource for researchers and students in genetics as well as clinicians.

CRISPR : methods and protocols

Автор: Magnus Lundgren
Название: CRISPR : methods and protocols
ISBN: 1493926861 ISBN-13(EAN): 9781493926862
Издательство: Springer
Рейтинг:
Цена: 23757.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This volume presents a list of cutting-edge protocols for the study of CRISPR-Cas defense systems and their applications at the genomic, genetic, biochemical and structural levels. CRISPR: Methods and Protocols guides readers through techniques that have been developed specifically for the analysis of CRISPR-Cas and techniques adapted from standard protocols of DNA, RNA and protein biology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, CRISPR: Methods and Protocols provides a broad list of tools and techniques to study the interdisciplinary aspects of the prokaryotic CRISPR-Cas defense systems.

Precision Medicine, CRISPR, and Genome Engineering

Автор: Stephen Tsang; George M. Church
Название: Precision Medicine, CRISPR, and Genome Engineering
ISBN: 331963903X ISBN-13(EAN): 9783319639031
Издательство: Springer
Рейтинг:
Цена: 22359.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book presents descriptive overviews of gene editing strategies across multiple species while also offering in-depth insight on complex cases of application in the field of tissue engineering and regenerative medicine.


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