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Human iPS Cells in Disease Modelling, Fukuda


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Автор: Fukuda
Название:  Human iPS Cells in Disease Modelling
ISBN: 9784431567394
Издательство: Springer
Классификация:

ISBN-10: 4431567399
Обложка/Формат: Soft cover
Страницы: 99
Вес: 1.96 кг.
Дата издания: 09.05.2018
Язык: English
Издание: Softcover reprint of
Иллюстрации: 12 tables, color; 2 tables, black and white; 12 illustrations, color; 1 illustrations, black and white; vii, 99 p. 13 illus., 12 illus. in color.
Размер: 235 x 155
Читательская аудитория: Professional & vocational
Основная тема: Life Sciences
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: Human iPS cells have a great potential to be cell sources for regenerative medicine because of the promise of infinite self-renewal and the capability to differentiate into multiple cell types. This book focuses on another great potential of human iPS cells, which is the establishment of human disease models using patient-specific iPS cells. Human iPS cells can be easily obtained from a patient’s somatic cells and provide the entire information on the patient’s genome. Accordingly, we can generate disease models for inheritable diseases in cell culture dishes using iPS cells. This is a quite new technique but holds tremendous potential for our increased understanding of pathogenesis, and will then be the basis for novel drug development industries. All the authors are leading researchers in this field and they have reported many kinds of patient-derived iPS cells. In this book, they introduce the aspects that could be recapitulated in terms of disease modelling as well as further innovative findings such as novel pathogenetic insights and novel therapies.
Дополнительное описание: Chapter 1 Recent Improvements and Emerging Issues in iPSC Generation for the Modeling of Disease.- Chapter 2 Cardiomyopathy.- Chapter 3 Modelling Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy with Patient-specific iPSCs.- Chapter 4 Cardiac Arr



Principles of Computational Cell Biology

Автор: Helms, Volkhard
Название: Principles of Computational Cell Biology
ISBN: 3527333584 ISBN-13(EAN): 9783527333585
Издательство: Wiley
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Цена: 11880.00 р.
Наличие на складе: Поставка под заказ.

Описание: This successful text, now in its 2nd ed. , provides an ideal introduction into the possibilities of modeling on a cell biology level. It extends the strengths of the first edition even further while keeping faithful to the trusted hands-on concept and keeping math to the minimum.

Cellular Biophysics and Modeling: A Primer on the Computational Biology of Excitable Cells

Автор: Greg Conradi Smith
Название: Cellular Biophysics and Modeling: A Primer on the Computational Biology of Excitable Cells
ISBN: 1107005361 ISBN-13(EAN): 9781107005365
Издательство: Cambridge Academ
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Цена: 15046.00 р.
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Описание: What every neuroscientist should know about the mathematical modeling of excitable cells. Combining empirical physiology and nonlinear dynamics, this text provides an introduction to the simulation and modeling of dynamic phenomena in cell biology and neuroscience. It introduces mathematical modeling techniques alongside cellular electrophysiology. Topics include membrane transport and diffusion, the biophysics of excitable membranes, the gating of voltage and ligand-gated ion channels, intracellular calcium signalling, and electrical bursting in neurons and other excitable cell types. It introduces mathematical modeling techniques such as ordinary differential equations, phase plane, and bifurcation analysis of single-compartment neuron models. With analytical and computational problem sets, this book is suitable for life sciences majors, in biology to neuroscience, with one year of calculus, as well as graduate students looking for a primer on membrane excitability and calcium signalling.

Cell-Based Assays Using iPSCs for Drug Development and Testing

Автор: Carl-Fredrik Mandenius; James A. Ross
Название: Cell-Based Assays Using iPSCs for Drug Development and Testing
ISBN: 1493994794 ISBN-13(EAN): 9781493994793
Издательство: Springer
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Цена: 16070.00 р.
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Описание: The volume presents a variety of protocols that will be useful to researchers working in the field of disease modeling, drug discovery, and the cell biology of various tissues. Chapters in this book cover topics such as requirements and preconditions for using human induced pluripotent cell lines in assay development; the culture of iPSCs and iPSC-derived cardiomyocytes by bioreactor technologies; distinctions between hepatocytes, vascular endothelial cells, cardiomyocytes, renal podocytes, and neurons; and high content assays of mitochondrial function and autophagy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cell-Based Assay using iPSCs for Drug Development and Testing: Methods and Protocols is a valuable resource for researchers working in this important and developing field of study.

Cell-Based Assays Using iPSCs for Drug Development and Testing

Автор: Carl-Fredrik Mandenius; James A. Ross
Название: Cell-Based Assays Using iPSCs for Drug Development and Testing
ISBN: 149399476X ISBN-13(EAN): 9781493994762
Издательство: Springer
Рейтинг:
Цена: 16070.00 р.
Наличие на складе: Поставка под заказ.

Описание:

The volume presents a variety of protocols that will be useful to researchers working in the field of disease modeling, drug discovery, and the cell biology of various tissues. Chapters in this book cover topics such as requirements and preconditions for using human induced pluripotent cell lines in assay development; the culture of iPSCs and iPSC-derived cardiomyocytes by bioreactor technologies; distinctions between hepatocytes, vascular endothelial cells, cardiomyocytes, renal podocytes, and neurons; and high content assays of mitochondrial function and autophagy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, Cell-Based Assay using iPSCs for Drug Development and Testing: Methods and Protocols is a valuable resource for researchers working in this important and developing field of study.
Recent Advances In Ipscs For Therapy ,9

Автор: Birbrair, Alexander
Название: Recent Advances In Ipscs For Therapy ,9
ISBN: 0128238828 ISBN-13(EAN): 9780128238820
Издательство: Elsevier Science
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Цена: 23075.00 р.
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Описание:

The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology.

iPSCs - Novel Concepts, Volume 15 addresses how important induced pluripotent stems cells are and how can they can help treat certain diseases.

Somatic cells can be reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells have been transforming biomedical research over the last 15 years. This volume will address the advances in research of how induced pluripotent stem cells are being used for treatment of different disorders, such as liver disease, type-1 diabetes, Parkinson's disease, macular degeneration of the retina and much more.

The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field.

Current Topics In Ipscs Technology,17

Автор: Birbrair, Alexander
Название: Current Topics In Ipscs Technology,17
ISBN: 0323998925 ISBN-13(EAN): 9780323998925
Издательство: Elsevier Science
Рейтинг:
Цена: 22738.00 р.
Наличие на складе: Поставка под заказ.

Описание: Luckily, the parking lot only deleted footage every three months because of the relatively heavy flow of tourism that took place at Cramond Ghost Island during the summer months. The old man in charge of the parking lot security cameras asked us why we needed the footage. Ethan told him that I met someone there at noon on a Saturday in July and that the police needed to verify that this meeting took place on that date. The old man had to review footage of the four Saturdays in July. He grumbled as he escorted us to a small viewing room at the rear end of the parking lot. Ethan and I sat down next to the old man as he began his search. He

Ipscs - State Of The Science

Автор: Birbrair, Alexander
Название: Ipscs - State Of The Science
ISBN: 0323857671 ISBN-13(EAN): 9780323857673
Издательство: Elsevier Science
Рейтинг:
Цена: 23075.00 р.
Наличие на складе: Поставка под заказ.

Описание: Luckily, the parking lot only deleted footage every three months because of the relatively heavy flow of tourism that took place at Cramond Ghost Island during the summer months. The old man in charge of the parking lot security cameras asked us why we needed the footage. Ethan told him that I met someone there at noon on a Saturday in July and that the police needed to verify that this meeting took place on that date. The old man had to review footage of the four Saturdays in July. He grumbled as he escorted us to a small viewing room at the rear end of the parking lot. Ethan and I sat down next to the old man as he began his search. He

Organoid Technology for Disease Modelling and Personalized Treatment

Автор: Yahaya Badrul Hisham
Название: Organoid Technology for Disease Modelling and Personalized Treatment
ISBN: 3030930556 ISBN-13(EAN): 9783030930554
Издательство: Springer
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Цена: 20962.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Organoid Technology for Disease Modelling and Personalised Treatment provides a comprehensive overview of current knowledge of the organoid as a human-organ-in-a-dish, a powerful new technology for studying fundamental aspects of human organ development and disease progression in the search for drugs for personalised treatment.

Cell Biology and Translational Medicine, Volume 12: Stem Cells in Development and Disease

Автор: Turksen Kursad
Название: Cell Biology and Translational Medicine, Volume 12: Stem Cells in Development and Disease
ISBN: 3030719324 ISBN-13(EAN): 9783030719326
Издательство: Springer
Цена: 23757.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание:

Anacйlia Matos, Silvia M M Magalhгes, Michael J Rauh - Immune dysregulation and recurring mutations in myelodysplastic syndromes pathogenesis.

Debojyoti De, Parimal Karmakar, Debalina Bhattacharya - Stem Cell Aging and Regenerative Medicine.

Drashti Desai, R. S. Gaud, Pravin Shende - Potential of Chimeric Antigen Receptor T-cells in cancer therapy.

Ekene Nweke, Deepak B. Thimiri Govindaraj - Drug sensitivity and drug repurposing platform for cancer precision medicine.

Fernando Faunes -Role and regulation of Lin28 in progenitor cells during central nervous system development.

Leila Taghiyar, Shahrbano Jahangir, Mojtaba Khozaei Ravari, Mohammad Amin Shamekhi, Mohamadreza Baghaban Eslaminejad -Cartilage Repair by Mesenchymal Stem Cell-Derived Exosomes: Preclinical and Clinical Trial Update and Perspectives.

Mabel Catalбn; Catalina Rodrнguez; Ivonne Olmedo; Javiera Carrasco-Rojas; Diego Rojas, Alfredo Molina-Berrнos; Mario Dнaz-Dosque Josй A. Jara - Kaempferol induce cell death and sensitizes human head and neck squamous cell carcinoma cell lines to cisplatin.

Marco Folci, Giacomo Ramponi, Enrico Brunetta - A comprehensive approach to Urticaria: from clinical presentation to modern biological treatments through pathogenesis.

Mrinal K Das, Taral R Lunavat, Hrvoje Miletic, Jubayer A Hossain - The potentials and pitfalls of using adult stem cells in cancer treatment.

Peyvand Parhizkar Roudsari, Sepideh Alavi-Moghadam, Mostafa Rezaei-Tavirani, Parisa Goodarzi, Akram Tayanloo-Beik, Forough Azam Sayahpour; Bagher Larijani, Babak Arjmand - The Outcome of Stem Cell-Based Therapies on the Immune Responses in Rheumatoid Arthritis.


Neural Stem Cells in Development, Adulthood and Disease

Автор: H. Georg Kuhn; Amelia J. Eisch
Название: Neural Stem Cells in Development, Adulthood and Disease
ISBN: 1493953613 ISBN-13(EAN): 9781493953615
Издательство: Springer
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Цена: 18284.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This comprehensive volume is the first to specifically target developing, adult and diseased neural stem cells.

Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease

Автор: Deric L. Wheeler; Yosef Yarden
Название: Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease
ISBN: 1493920529 ISBN-13(EAN): 9781493920525
Издательство: Springer
Рейтинг:
Цена: 22203.00 р.
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Описание: Receptor Tyrosine Kinase: Structure, Functions and Role in Human Disease, for the first time, systematically covers the shared structural and functional features of the RTK family.

Induced Pluripotent Stem Cells and Human Disease

Автор: Turksen
Название: Induced Pluripotent Stem Cells and Human Disease
ISBN: 1071625845 ISBN-13(EAN): 9781071625842
Издательство: Springer
Рейтинг:
Цена: 16769.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This detailed volume presents a series of protocols that are representative of recent developments and improvements in induced pluripotent stem cells (iPS cells) and corresponding human disease models.


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