Practical application of supercritical fluid chromatography for pharmaceutical research and development, Garg, Sumit, Md (vice Chair Of Clinical Ophthalmology Medical Director Professor - Cataract, Corneal, And Refractive Surgery Garvin Herbert Eye Instit
Автор: Rossй Gйrard Название: Supercritical Fluid Chromatography: Volume 1 ISBN: 3110500752 ISBN-13(EAN): 9783110500752 Издательство: Walter de Gruyter Рейтинг: Цена: 13008.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Poole, Colin F Название: Supercritical Fluid Chromatography ISBN: 0128092076 ISBN-13(EAN): 9780128092071 Издательство: Elsevier Science Рейтинг: Цена: 24423.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Supercritical fluid chromatography (SFC) is a rapidly developing laboratory technique for the separation and identification of compounds in mixtures. Significant improvements in instrumentation have rekindled interest in SFC in recent years and enhanced its standing in the scientific community. Many scientists are familiar with column liquid chromatography and its strengths and weaknesses, but the possibilities brought to the table by SFC are less well-known and are underappreciated.
Supercritical Fluid Chromatography is a thorough and encompassing reference that defines the concept of contemporary practice in SFC and how it should be implemented in laboratory science. Given the changes that have taken place in SFC, this book presents contemporary aspects and applications of the technique and introduces SFC as a natural solution in the larger field of separation science. The focus on state-of-the-art instrumental SFC distinguishes this work as the go-to reference work for those interested in implementing the technique at an advanced level.
Edited and authored by world-leading chromatography experts
Provides comprehensive coverage of SFC in a single source
Extensive referencing facilitates identification of key research developments
More than 200 figures and tables aid in the retention of key concepts
Explains why modern supercritical fluid chromatography (SFC) is the leading "green" analytical and purification separations technology.
Modern supercritical fluid chromatography (SFC) is the leading method used to analyze and purify chiral and achiral chemical compounds, many of which are pharmaceuticals, pharmaceutical candidates, and natural products including cannabis-related compounds. This book covers current SFC instrumentation as it relates to greater robustness, better reproducibility, and increased analytical sensitivity.
Modern Supercritical Fluid Chromatography: Carbon Dioxide Containing Mobile Phases covers the history, instrumentation, method development and applications of SFC. The authors provided readers with an overview of analytical and preparative SFC equipment, stationary phases, and mobile phase choices. Topics covered include: Milestones of Supercritical Fluid Chromatography; Physical Properties of Supercritical Fluids; Instrumentation for SFC; Detection in SFC; Achiral SFC Method Development; Chiral SFC Method Development; and Preparative Scale SFC. The book also includes highlights of modern applications of SFC in the final chapters--namely pharmaceuticals, consumer products, foods, polymers, petroleum-related mixtures, and cannabis--and discusses the future of SFC.
Provides a clear explanation of the physical and chemical properties of supercritical fluids, which gives the reader a better understanding of the basis for improved performance in SFC compared to HPLC and GC
Describes the advantages of SFC as a green alternative to HPLC and GC for the analysis of both polar, water-soluble, and non-polar analytes
Details both achiral and chiral SFC method development, including modifiers, additives, the impact of temperature and pressure, and stationary phase choices
Details why SFC is the premier modern preparative chromatographic technique used to purify components of mixtures for subsequent uses, both from performance and economic perspectives
Covers numerous detectors, with an emphasis on SFC-MS, SFC-UV, and SFC-ELSD (evaporative light scattering detection)
Describes the application of SFC to numerous high-value application areas
Modern Supercritical Fluid Chromatography: Carbon Dioxide Containing Mobile Phases will be of great interest to professionals, students, and professors involved in analytical, bioanalytical, separations science, medicinal, petroleum, and environmental chemistries. It will also appeal to pharmaceutical scientists, natural-product scientists, food and consumer-products scientists, chemical engineers, and managers in these areas.
Автор: Rossй Gйrard Название: Supercritical Fluid Chromatography: Volume 2 ISBN: 3110618931 ISBN-13(EAN): 9783110618938 Издательство: Walter de Gruyter Цена: 11861.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The use of supercritical fluids in analytical chemistry is still grow- ing. The advantages of supercritical CO , such as having dif- 2 fusivity like a gas and solvating power depending on temperature and pressure, are also valid for other fluids and modified fluids.
Автор: Inamuddin, Asiri Abdullah M. Название: Advanced Nanotechnology and Application of Supercritical Fluids ISBN: 3030449866 ISBN-13(EAN): 9783030449865 Издательство: Springer Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Globalization and industrialization involve a number of reactions, products, extractions, and separations that require the use of organic solvents. These solvents are responsible for a number of ecological concerns, including atmospheric and land toxicity. Conventional organic solvents are regarded as volatile organic compounds; some are even limited due to their potential for ozone layer depletion. While supercritical liquids exhibit physical properties that could make them ideal substitutes for these volatile compounds, there is particular interest in the use of carbon dioxide as a solvent of crude material. In particular, carbon dioxide has apparent 'green' properties, like its noncombustible nature, the fact that it is generally nonpoisonous, and its relative inertness. Thus, the use of supercritical carbon dioxide can provide practical improvements to the sustainability of industrial products and processes.
This book provides in-depth literature in the area of industrial green processes, focusing on the separation, purification, and extraction of compounds utilizing supercritical carbon dioxide as a green solvent.
Industrial Scale Application of Subcritical and Supercritical Fluids for Design of Products fills the gap between fundamentals and industrial implantation of various high-pressure process technologies. The book covers the design, start-up and maintenance of real industrial plants, also providing readers with insights on their construction and operational essentials. It is ideal for chemical engineers who operate high pressure units and different researchers who create supercritical fluid technology to solve problems surrounding product fractionation, product formulation, synthesis in SCF, and product development using supercritical fluids technologies.
There are some books that describe high pressure technologies and research in the area of sub- and supercritical fluids, but this book presents fundamental data on thermodynamics and mass transfer, topics that are absolutely essential for the design of industrial plants.
Автор: Inamuddin, Asiri Abdullah M. Название: Advanced Nanotechnology and Application of Supercritical Fluids ISBN: 3030449831 ISBN-13(EAN): 9783030449834 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Globalization and industrialization involve a number of reactions, products, extractions, and separations that require the use of organic solvents. These solvents are responsible for a number of ecological concerns, including atmospheric and land toxicity. Conventional organic solvents are regarded as volatile organic compounds; some are even limited due to their potential for ozone layer depletion. While supercritical liquids exhibit physical properties that could make them ideal substitutes for these volatile compounds, there is particular interest in the use of carbon dioxide as a solvent of crude material. In particular, carbon dioxide has apparent ‘green’ properties, like its noncombustible nature, the fact that it is generally nonpoisonous, and its relative inertness. Thus, the use of supercritical carbon dioxide can provide practical improvements to the sustainability of industrial products and processes. This book provides in-depth literature in the area of industrial green processes, focusing on the separation, purification, and extraction of compounds utilizing supercritical carbon dioxide as a green solvent.
Описание: Illustrates the state of the art in supercritical water cooled reactor (SCWR) research and development. This is a key supporting publication to researchers and engineers pursuing the development of SCWRs or equipment/components operating at supercritical pressures.
Описание: The rapid pace of technological change constantly gives rise to new ethical dilemmas. This provides a practical introduction for engineering students that emphasizes ethical decision-making. The authors situate engineering ethics in the wider context of business and environmental ethics and guide students through case studies emphasizing value conflicts often encountered in engineering.
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