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Therapeutic Applications of Dopamine D3 Receptor Function, Boileau


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Цена: 20962.00р.
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Автор: Boileau
Название:  Therapeutic Applications of Dopamine D3 Receptor Function
ISBN: 9783031230578
Издательство: Springer
Классификация:


ISBN-10: 3031230574
Обложка/Формат: Hardback
Страницы: 275
Вес: 0.59 кг.
Дата издания: 17.01.2023
Серия: Current Topics in Behavioral Neurosciences
Язык: English
Издание: 1st ed. 2023
Иллюстрации: 30 tables, color; 1 illustrations, black and white; viii, 275 p. 1 illus.
Размер: 235 x 155
Читательская аудитория: Professional & vocational
Основная тема: Biomedicine
Подзаголовок: New insight after 30 years of research
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: The CTBN volume Therapeutic Applications of Dopamine D3 Receptor Function reviews the state of the knowledge on the dopamine D3 receptor and its role in human behavior and disease (i.e.: neuropsychiatric illnesses including schizophrenia, mood disorders, Parkinson’s disease, restless legs syndrome, addictions and substance use disorders). The volume is written by leading experts across multidisciplinary areas (imaging, biobehavioral testing and clinical trials, preclinical models / molecular pharmacology) converging on the therapeutic implications / potential of the D3 receptor. The D3 dopamine receptor is a member of the D2-like family of G protein-coupled receptors. It was cloned and characterized almost 25 years ago. A key feature of the D3 dopamine receptor system, which has attracted considerable attention, is its anatomical localization remarkably restricted to the limbic circuitry. This has spurred the hypothesis that D3 involvement could contribute to the pathophysiology of neuropsychiatric disorders (or to some features of neuropsychiatric disorders), including but not limited to psychosis, addictions and substance abuse, mood and movement disorders.
Дополнительное описание: Preface.- A Historic Review of the D3 Dopamine System from D3 Cloning to Clinical Trials in Schizophrenia and Drug Addiction.- Location, Location, Location: The Expression of D3 Dopamine Receptors in the Nervous System.- Recent Advances in Dopamine D3 Rec



The Dopamine Receptors

Автор: Kim A. Neve (Ed.)
Название: The Dopamine Receptors
ISBN: 1603273328 ISBN-13(EAN): 9781603273329
Издательство: Springer
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Цена: 43184.00 р.
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Описание: This revised book serves as a reference work on dopamine receptors while also highlighting the areas of research that are most active today. There are new chapters on dopamine receptor-interacting proteins and on dopamine receptor oligomerization.

Behavioral Neurobiology of GABAB Receptor Function

Автор: Vlachou Styliani, Wickman Kevin
Название: Behavioral Neurobiology of GABAB Receptor Function
ISBN: 3030913341 ISBN-13(EAN): 9783030913342
Издательство: Springer
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Цена: 20962.00 р.
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Описание: It has been almost forty years since Norman G. Bowery discovered and named this “non-GABAA” receptor the GABAB receptor. It has been almost ten years since the last comprehensive book presentation focused on GABAB receptors. The main goal of this book is to provide the field with a contemporary and comprehensive perspective on the GABAB receptor, its physiological relevance, and its therapeutic potential. The volume is organized into introductory and special interest sections presented by experts who study the GABAB receptor from structural, signaling, pharmacologic, physiological, pathophysiological, and therapeutic perspectives. The book aims to appeal to a broad spectrum of biomedical and clinical scientists - any scholars with an interest in GABAB receptor. The editors hope readers find this work to be thought-provoking, instructive, and informative.

Dopamine Receptor Agonists

Автор: George Poste; Stanley T. Crooke
Название: Dopamine Receptor Agonists
ISBN: 1475703120 ISBN-13(EAN): 9781475703122
Издательство: Springer
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Цена: 16979.00 р.
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Описание: Dopamine, in addition to its importance as a precursor of norepinephrine, is now known to be an important neurotransmitter in regulating functional activities in a number of major organ systems, including the central ner- vous system.

Dopamine Receptor Technologies

Автор: Mario Tiberi
Название: Dopamine Receptor Technologies
ISBN: 149394889X ISBN-13(EAN): 9781493948895
Издательство: Springer
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Цена: 15372.00 р.
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Описание: To foster a better understanding of dopamine receptor functionality, this detailed volume creates an interface between updated classical methods and new emerging technologies heretofore not available to new or seasoned researchers.

Chemokine Receptors and NeuroAIDS

Автор: Olimpia Meucci
Название: Chemokine Receptors and NeuroAIDS
ISBN: 1489984879 ISBN-13(EAN): 9781489984876
Издательство: Springer
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Цена: 23757.00 р.
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Описание: Since their discovery as HIV co-receptors in 1996, chemokine receptors have been widely studied within the field of HIV pathogenesis, including neuroAIDS. However, though their role in infection of target cells and in inflammatory/immune responses is relatively well-characterized, their relevance with respect to neuropathogenesis is still unclear.

G-Protein-Coupled Receptor Dimers

Автор: Katharine Herrick-Davis; Graeme Milligan; Giuseppe
Название: G-Protein-Coupled Receptor Dimers
ISBN: 3319867954 ISBN-13(EAN): 9783319867953
Издательство: Springer
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Цена: 20962.00 р.
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Описание: G-protein-coupled receptors (GPCRs) are believed to be the largest family of membrane proteins involved in signal transduction and cellular responses.

Gabab Receptor

Автор: Colombo Giancarlo
Название: Gabab Receptor
ISBN: 3319834282 ISBN-13(EAN): 9783319834283
Издательство: Springer
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Цена: 20962.00 р.
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Описание: An up-to-date comprehensive overview of the GABA B receptor system with a particular focus on the most recent therapeutic applications and potential. This receptor system has recently been implicated in several diseases and disorders including gastroesophageal reflux disease, epilepsy, mood disorders, depression, and alcohol and substance use disorder. The authors, leading researchers in the field, explore a number of approaches, including medicinal chemistry, molecular biology, physiology, and preclinical and clinical pharmacology. This overview provides a translational perspective on the potential of the GABA B receptor pharmacology.

Central D1 Dopamine Receptors

Автор: M. J. Goldstein
Название: Central D1 Dopamine Receptors
ISBN: 1489927255 ISBN-13(EAN): 9781489927255
Издательство: Springer
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Цена: 6986.00 р.
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Описание: The development of a selective D1 dopamine (DA) receptor antagonist SCH 23390 stimulated a number of studies on the functions mediated by central DA receptor subtypes.

Central Functions of the Ghrelin Receptor

Автор: Jeanelle Portelli; Ilse Smolders
Название: Central Functions of the Ghrelin Receptor
ISBN: 1493908227 ISBN-13(EAN): 9781493908226
Издательство: Springer
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Цена: 23757.00 р.
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Описание: The Ghrelin receptor was identified before its natural ligand ghrelin. This receptor is found both centrally and peripherally, and has been shown to affect various processes, such as food intake, gut motility, memory, glucose and lipid metabolism, cardiovascular performances, reproduction, memory, and immunological responses, amongst others. The functions of the ghrelin receptor in the central nervous system are numerous and are still being explored. In this book we specifically focus on the various roles of the ghrelin receptor in the central nervous system. In a first set of chapters, the book will focus on the discovery and the properties of this intriguing constitutively active G-protein coupled receptor, on its multiple intracellular transduction mechanisms and the various subtypes of the currently known ghrelin receptor complexes. Next, the book will elaborate on the mitochondrial mechanisms regulated by the ghrelin receptor, its role in feeding and drug addictive mechanisms, memory, sleep and arousal. The final chapters focus on the potential of this receptor as a target for the treatment of neurological disorders including Parkinson’s disease, epilepsy, anxiety and depression.

G-Protein-Coupled Receptor Dimers

Автор: Katharine Herrick-Davis; Graeme Milligan; Giuseppe
Название: G-Protein-Coupled Receptor Dimers
ISBN: 3319601725 ISBN-13(EAN): 9783319601724
Издательство: Springer
Рейтинг:
Цена: 27950.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: G-protein-coupled receptors (GPCRs) are believed to be the largest family of membrane proteins involved in signal transduction and cellular responses.

Central Functions of the Ghrelin Receptor

Автор: Jeanelle Portelli; Ilse Smolders
Название: Central Functions of the Ghrelin Receptor
ISBN: 1493955349 ISBN-13(EAN): 9781493955343
Издательство: Springer
Рейтинг:
Цена: 19589.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: The Ghrelin receptor was identified before its natural ligand ghrelin.

Functional Selectivity of G Protein-Coupled Receptor Ligands

Автор: Kim Neve
Название: Functional Selectivity of G Protein-Coupled Receptor Ligands
ISBN: 1493961160 ISBN-13(EAN): 9781493961160
Издательство: Springer
Рейтинг:
Цена: 26120.00 р.
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Описание: In Functional Selectivity of G Protein-Coupled Receptors, experts review the work that demonstrated the existence of functional selectivity, placed it within a theoretical framework, and provided a mechanistic basis for the phenomenon.


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