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Protein Misfolding in Neurodegenerative Diseases, Sewell, Robert D. E.


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Автор: Sewell, Robert D. E.
Название:  Protein Misfolding in Neurodegenerative Diseases
ISBN: 9780849373107
Издательство: Taylor&Francis
Классификация:
ISBN-10: 0849373107
Обложка/Формат: Hardback
Страницы: 592
Вес: 1.26 кг.
Дата издания: 03.12.2007
Язык: English
Размер: 234 x 156 x 32
Читательская аудитория: Postgraduate, research & scholarly
Подзаголовок: Mechanisms and therapeutic strategies
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Поставляется из: Европейский союз


Protein Misfolding in Neurodegenerative Diseases

Название: Protein Misfolding in Neurodegenerative Diseases
ISBN: 036738812X ISBN-13(EAN): 9780367388126
Издательство: Taylor&Francis
Рейтинг:
Цена: 9798.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание:

Research focused on protein folding, misfolding, and aggregation is leading to major advances across biochemistry and medicine. The elucidation of a folding code is proving to be of extreme importance in the postgenomic era, where a number of orphan genes have been identified for which no clear function has yet been established. This research is starting to shed light on the molecular and biochemical basis of a number of neurodegenerative diseases of dramatic impact.

Protein Misfolding in Neurodegenerative Diseases: Mechanisms and Therapeutic Strategies addresses key issues concerning protein misfolding and aggregation in neurodegenerative diseases. Building on recent developments, including the recognition of protein misfolding as both a marker and a causal agent, the text presents the work of those who are actively pursuing more effective treatments, as well as preventative measures, and a possible cure. These include the use of molecular chaperones to control misfolding and novel pharmaceuticals, as well as the potential role of various inhibitors and NSAIDS.

A Comprehensive Multifaceted Examination of the Complex Causal Agents Implicated in Protein Misfolding

Divided into five sections, this groundbreaking text provides up-to-date accounts for Alzheimer's, Parkinson's, Huntington's, Amyotrophic Lateral Sclerosis and Transmissible Spongiform Encephalitis. It also explores the highly likelihood that multiple factors, including oxidative stress, play a role in these complex diseases.

Protein Quality Control in Neurodegenerative Diseases

Автор: Richard I. Morimoto; Yves Christen
Название: Protein Quality Control in Neurodegenerative Diseases
ISBN: 3642447066 ISBN-13(EAN): 9783642447068
Издательство: Springer
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Цена: 19589.00 р.
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Описание: Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimer`s disease, Parkinson`s disease, amyotrophic lateral sclerosis, Huntington`s disease, and other diseases of protein conformation.

Quality Control of Cellular Protein in Neurodegenerative Disorders

Автор: Md. Sahab Uddin, Ghulam Md Ashraf
Название: Quality Control of Cellular Protein in Neurodegenerative Disorders
ISBN: 1799813177 ISBN-13(EAN): 9781799813170
Издательство: Mare Nostrum (Eurospan)
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Цена: 39640.00 р.
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Описание: A hallmark of neurodegenerative proteinopathies is the formation of misfolded protein aggregates that cause cellular toxicity. Though multiple factors like aging, oxidative stress, gene inconsistency, etc. are responsible for the dysfunction of the protein quality control system, targeting protein quality control has become an auspicious approach to block the propagation of neurodegeneration.

Quality Control of Cellular Protein in Neurodegenerative Disorders provides diverse aspects exploring the theoretical and practical methods of protein quality control systems and potential therapeutic approaches to halt the development and propagation of neurodegenerative disorders. Featuring coverage on a broad range of topics such as cellular chaperones, protein folding, and stress signaling, this book is ideally designed for neurobiologists, neuropsychologists, neurophysiologists, medical professionals, neuropathologists, researchers, academicians, students, and practitioners engaged in studies of the protein quality control system in neuronal cells.

Genedis 2020: Genetics and Neurodegenerative Diseases

Автор: Vlamos Panayiotis
Название: Genedis 2020: Genetics and Neurodegenerative Diseases
ISBN: 3030787869 ISBN-13(EAN): 9783030787868
Издательство: Springer
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Цена: 41925.00 р.
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Описание: 1-Attitudes and smoking prevalence among undergraduate students in central Greece.

2-Care of patients with Alzheimer's disease

3-Regulation of antioxidant enzymes levels in rat brain

4-NIRS-based assessment of cerebral oxygenation during high definition anodal transcranial direct current stimulation in patients with posttraumatic encephalopathy.

5-Cerebral critical closing pressure at concomitant traumatic brain injury.

6-The role of inflammatory biomarkers as a diagnostic tool for possible late-life cognitive decline and dementias

7-The Development of Antisense RNA Treatments using Engineered Protein Substrates

8-Biomarker-driven analysis using high-throughput approaches in neuroinflammation and neurodegenerative diseases

9-Sensitive and Stereo specific high-performance liquid chromatographic method for flurbiprofen in human plasma

10-Genotypic and Clinical Analysis of a Thalassemia Major Cohort: An Observational Study

11-Design and Validation of a New Diagnostic Tool for the Differentiation of Pathological Voices in Parkinsonian Patients

12-Effects of an 8-Week Stress Management Program in Women with Breast Cancer: A Randomized Controlled Trial

13-The Rosenberg Self-Esteem Scale: Translation and Validation in the Greek Language in Adolescents

14-Stress system activation analysis in Greek female adolescents: a bioimpedance study

15-Kisspeptin and the genetic obesity interactome

16-The importance of diagnostic and prognostic biomarkers identification and classification towards understanding ALS pathogenesis.

17-Entropy in Cardiac Autonomic Nervous System of Adolescents with General Learning Disabilities or Dyslexia

18-Ebola virus disease and current therapeutic strategies; A review

19-Hyperbaric Oxygen Therapy effect on "Kinesia Paradoxa" Brain Circuits

20-Early and Very Early GRIM19 and MCL1 Expression are Correlated to Late Acquired Prednisolone Effects in a T-Cell Acute Leukemia Cell Line

21-Phospholipid Fatty Acid Profile of Spirulina platensis

22-Chronic systemic inflammation measured by bioimpedance technology before and after sleeve gastrectomy: a feasibility study

23-Synthesis and Biological Evaluation Substituted Thiophene Derivatives

24-Force spectroscopy in mechanical protein domains unfolding

25-Investigating the genetic component of Parkinson's Disease.

26-Urticaria from the Neurodermatological Perspective: A Temporal Analysis of Urticaria and Cognition

27-Novel Low-Noise CMOS Bioamplifier for the Characterization of Neurodegenerative Diseases

28-The Kentucky Inventory of Mindfulness Skills in Greek Undergraduate and Postgraduate Students

29-Synthesis, in silico stuiesand biological evaluation of 1, 3,4 oxadiazino indole derivatives

30-Designing and screening of new schiff bases of indole derivatives for anti-bacterial activity by in-silico methods and docking studies

31-Use of vitamin D bolus in fortified juice for improving vitamin D status in children with Cerebral Palsy.

32-Microbes and the games they play

33-Impurity Profiling and Identification of 2,6 diisopropylphenol by Raman spectroscopy

34-Cultural Accommodation of the Strengthening Families Program for Parents and Young Adolescents 10-14: Greek Phase I & II Study

35-The effect of nutrients on Alzheimer's disease biomarkers: A metabolomic approach

36-The impact of exercising in the quality of life of people with Aementia-Alzheimer disease

37-Advanced Health Technologies and Nanotechnologies in Neurodegenerative Diseases

38-Phenotype and genotype study in a case of frontometaphyseal dysplasia 1

39-Craniofacial and neurological phenotype in a case of oculodentodigital syndrome

40-Clinical and molecular study of common thrombophilia mutation prothrombin G2
Neurodegenerative Diseases Biomarkers: Towards Translating Research to Clinical Practice

Автор: Peplow Philip V., Martinez Bridget, Gennarelli Thomas A.
Название: Neurodegenerative Diseases Biomarkers: Towards Translating Research to Clinical Practice
ISBN: 1071617117 ISBN-13(EAN): 9781071617113
Издательство: Springer
Цена: 27950.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This detailed book aims to provide an overview of novel bioinformatics resources for exploring diverse aspects of RNA biology. This edition focuses on methods dealing with non-coding RNA (miRNAs, circRNAs or lncRNAs), RNA modifications (m6A or RNA editing), single cell RNA-seq and statistical models to handle count data from RNA-seq experiments.

Stem Cell-based Therapy for Neurodegenerative Diseases

Автор: Han Fabin, Lu Pengzhe (Paul)
Название: Stem Cell-based Therapy for Neurodegenerative Diseases
ISBN: 9811543720 ISBN-13(EAN): 9789811543722
Издательство: Springer
Цена: 13974.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book reviews the state-of-the-art in stem-cell-based therapies for neurodegenerative diseases, and highlights advances in both animal models and clinical trials.

Biomedical Applications of Acridines

Автор: Jan Je?ek; Jan Hlav??ek; Jaroslav ?ebest?k
Название: Biomedical Applications of Acridines
ISBN: 3319876805 ISBN-13(EAN): 9783319876801
Издательство: Springer
Рейтинг:
Цена: 19564.00 р.
Наличие на складе: Нет в наличии.

Описание: This book describes applications of acridines for the treatment of various neurodegenerative diseases, such as Alzheimer`s disease, Parkinson`s disease, and various prion diseases, and discusses the potential of acridines in neuro-regenerative medicine.

Stem Cell-Based Therapy for Neurodegenerative Diseases

Автор: Han Fabin, Lu Pengzhe (Paul)
Название: Stem Cell-Based Therapy for Neurodegenerative Diseases
ISBN: 9811543690 ISBN-13(EAN): 9789811543692
Издательство: Springer
Цена: 13974.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book reviews the state-of-the-art in stem-cell-based therapies for neurodegenerative diseases, and highlights advances in both animal models and clinical trials.

Neurodegenerative Disorders as Systemic Diseases

Автор: Wada Keiji
Название: Neurodegenerative Disorders as Systemic Diseases
ISBN: 4431562982 ISBN-13(EAN): 9784431562986
Издательство: Springer
Рейтинг:
Цена: 20962.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book sheds new light on neurodegenerative disorders as systemic diseases. Classically, neuronal cell death was a hallmark of such disorders. However, it has become evident that neural dysfunction is more important in the pathophysiology of neurodegenerative disorders. More recently, the prionoid-spreading hypothesis of disease-causing molecules has attracted a great deal of attention. Therapeutic strategies thus must be reconsidered in the light that neurodegenerative disorders are indeed systemic diseases. The first part of this book introduces the concept of neurodegeneration in biology and pathophysiology. The second part focuses on clinical evaluation and biomarkers from the perspective of this new concept, while the third summarizes the risk factors of neurodegeneration. The fourth part of this work indicates future directions of treatment, and the final part discusses health promotion for prevention and quality of life. This book will be of interest to both researchers and medical personnel, and provides a fresh approach to neurodegenerative diseases, paving the way to new research and improved quality of health care for patients.

Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection

Автор: Alexzander A.A. Asea; Ian R. Brown
Название: Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection
ISBN: 9048178134 ISBN-13(EAN): 9789048178131
Издательство: Springer
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Цена: 32004.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book reviews current progress on heat shock proteins in the brain and their implications for neurodegenerative diseases, neuroprotection, aging and control of life span. It features contributions from laboratories from major universities around the world.

Molecular Biology Of Neurodegenerative Diseases,107

Автор: Teplow, David B.
Название: Molecular Biology Of Neurodegenerative Diseases,107
ISBN: 0123858836 ISBN-13(EAN): 9780123858832
Издательство: Elsevier Science
Рейтинг:
Цена: 17517.00 р.
Наличие на складе: Нет в наличии.

Описание: Neurodegenerative diseases result in progressive degeneration and/or death of nerve cells which leads to problems with movement and mental functioning. This volume reviews the research and developments in the molecular biology of neurodegenerative diseases.

Current Challenges In Cell Therapy For Neurodegenerative Diseases,166

Автор: Lane, Emma
Название: Current Challenges In Cell Therapy For Neurodegenerative Diseases,166
ISBN: 0323989373 ISBN-13(EAN): 9780323989374
Издательство: Elsevier Science
Рейтинг:
Цена: 24423.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: My experience as a State Correction Officer inside New Yorks Prisons. As you read Paul Harringtons day-to-day and month-to-month experiences within the states prison system, you will see a broken system one that is full of loopholes, lies, cover-ups and corruption. This system is full of daily violence and numerous officers are injured by violent inmates. Each officer has their unique view of the prison system. Here, Harrington wishes to share his perspective of how different administrations created changes in the daily operations at Fishkill Correctional Facility, where he was stationed after a 15-month stint at Sing Sing. Not every day was


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