Автор: Simon Название: Design and Analysis of DNA Microarray Investigations ISBN: 0387001352 ISBN-13(EAN): 9780387001357 Издательство: Springer Рейтинг: Цена: 20896.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book
discusses the analysis of gene expression profile data from DNA micorarray studies and the design of such studies. The book will address design and analysis issues for both of the
major classes of DNA microarrays, the cDNA microarrays and the oligonucleotide arrays. DNA microarrays are a new technology that is revolutionizing biological and biomedical
research.
Most biologists are trying to analyze their own data using a variety of commercial and public domain software. This book will provide an authoritative review of the
methods available and present it in a manner that is intelligible to biologists.
Автор: Bilge Sener Название: Innovations in Chemical Biology ISBN: 9048177766 ISBN-13(EAN): 9789048177769 Издательство: Springer Рейтинг: Цена: 33401.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This proceedings volume of the 9th Eurasia Conference details advances in chemical biology. It includes coverage of analytical chemistry, biochemical technology, bioinformatics, catalysis and nanotechnology, bioorganic and bioinorganic chemistry.
Описание: This new book provides insight with scientific evidence on the use of medicinal plants in the treatment of certain diseases. It describes bioactive compounds of marine and plant origin that have been discovered to be advantageous for human health.
Автор: Mahapatra, Debarshi Kar Название: Handbook of Research on Medicinal Chemistry ISBN: 177463662X ISBN-13(EAN): 9781774636626 Издательство: Taylor&Francis Рейтинг: Цена: 12707.00 р. Наличие на складе: Поставка под заказ.
Описание: <em>Innovations in Data Methodologies and Computational Algorithms for Medical Applications</em> offers the most cutting edge research in the field, offering insights into case studies and methodologies from around the world. The text details the latest developments and will serve as a vital resource to practitioners and academics alike in the burgeoning field of medical applications of technologies. As security and privacy improve, Electronic Health Records and informatics in the medical field are becoming ubiquitous, and staying abreast of the latest information can be difficult. This volume serves as a reference handbook and theoretical framework for the future of the field.
Название: Microarray Innovations ISBN: 0367385813 ISBN-13(EAN): 9780367385811 Издательство: Taylor&Francis Рейтинг: Цена: 9798.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
In recent years, high-density DNA microarrays have revolutionized biomedical research and drug discovery efforts by the pharmaceutical industry. Their efficacy in identifying and prioritizing drug targets based on their ability to confirm a large number of gene expression measurements in parallel has become a key element in drug discovery. Microarray Innovations: Technology and Experimentation examines the incredibly powerful nature of array technology and the ways in which it can be applied to understanding the genomic basis of disease.
Explores a myriad of applications in use today
This volume explores recent innovations in the microarray field and tracks the evolution of the major platforms currently used. The international panel of contributors presents a survey of the past five years' research and advancements in microarray methods and applications and their usage in drug discovery and biomedical research. The contributions discuss improvements in automation (array fabrication and hybridization), new substrates for printing arrays, platform comparisons and contrasts, experimental design, and data normalization and mining schemes. They also review epigenomic array studies, electronic microarrays, comparative genomic hybridization, microRNA arrays, and mutational analyzes. In addition, the book provides coverage of important clinical diagnostic arrays, protein arrays, and neuroscience applications.
Examines improved methodologies
As microarrays have evolved steadily over time from archetypical in-house complementary DNA (cDNA) arrays to robust commercial oligonucleotide platforms, there has been a migration to higher density biochips with increasing content and better analytical methodologies. This compendium summarizes the vast advances that have been made in this technology, highlighting the supreme advantages of microarray-based appro
Автор: Uwe R. M?ller; Miguel Nicolau Название: Microarray Technology and Its Applications ISBN: 3642061826 ISBN-13(EAN): 9783642061820 Издательство: Springer Рейтинг: Цена: 30606.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Ten years ago micro- ray technology emerged as a new and powerful tool to study nucleic acid - quences in a highly multiplexed manner, and has since found equally exciting and useful applications in the study of proteins, metabolites, toxins, viruses, whole cells and even tissues.
Автор: Jang B. Rampal Название: Microarrays ISBN: 1617376639 ISBN-13(EAN): 9781617376634 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: These two volumes present information in designing and fabricating arrays and binding studies with biological analytes. This is done while providing the reader with a broad description of microarray technology tools and their potential applications.
Автор: Pokorski Mieczyslaw Название: Advancements and Innovations in Health Sciences ISBN: 3030327906 ISBN-13(EAN): 9783030327903 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book focuses on recent advances regarding clinical conditions and ailments whose mechanisms remain unclear, limiting our ability to treat them. The respective chapters address a range of multidisciplinary topics related to timely or emergent research areas, such as osteoporosis in postmenopausal women, the optimal surgical procedures for vertebral compression fractures, novel rehabilitative approaches in pelvic muscle training in case of urinary incontinence, and a rational approach to balneotherapy not only for the skin but also other organ systems disorders. Alterations in the endocrine function during strenuous physical activity at high altitude – a multi-stressor environment comprising hypobaric hypoxia, exercise, and nutritional changes – are presented as well. Other articles provide evidence-based insights into the diagnosis, mechanisms, and clinical course of respiratory infections in children such as bronchiolitis, pneumonia, and influenza. Finally, the pros and cons of e-health are discussed; a rapidly growing area based on the use of information and communication technology to streamline the flow of health information and patient-healthcare provider connections. The content is a well-structured blend of research and practical aspects, as well as updates on cutting-edge developments. All these essential topics are presented in a format suitable for medical professionals engaged in day-to-day patient care and therapy, as well as researchers, academics, and physiotherapists.
Автор: Damelin Marc Название: Innovations for Next-Generation Antibody-Drug Conjugates ISBN: 3319781537 ISBN-13(EAN): 9783319781532 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Antibody-drug conjugates (ADCs) stand at the verge of a transformation. Scores of clinical programs have yielded only a few regulatory approvals, but a wave of technological innovation now empowers us to overcome past technical challenges. This volume focuses on the next generation of ADCs and the innovations that will enable them. The book inspires the future by integrating the field’s history with novel strategies and cutting-edge technologies. While the book primarily addresses ADCs for solid tumors, the last chapter explores the emerging interest in using ADCs to treat other diseases. The therapeutic rationale of ADCs is strong: to direct small molecules to the desired site of action (and away from normal tissues) by conjugation to antibodies or other targeting moieties. However, the combination of small and large molecules imposes deep complexity to lead optimization, pharmacokinetics, toxicology, analytics and manufacturing. The field has made significant advances in all of these areas by improving target selection, ADC design, manufacturing methods and clinical strategies. These innovations will inspire and educate scientists who are designing next-generation ADCs with the potential to transform the lives of patients.
Handbook of Innovations in CNS Regenerative Medicine provides a comprehensive overview of the CNS regenerative medicine field. The book describes the basic biology and anatomy of the CNS and how injury and disease affect its balance and the limitations of the present therapies used in the clinics. It also introduces recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies. Finally, the book presents successful cases of translation of basic research to first-in-human trials and the steps needed to follow this path.
Areas such as cell transplantation approaches, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies are key in regenerative medicine are covered in the book, along with regulatory and ethical issues.
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