Handbook of Research on Medicinal Chemistry, Mahapatra, Debarshi Kar
Автор: Peacock, Janet L. Название: Oxford handbook of medical statistics - 2e. ISBN: 0198743580 ISBN-13(EAN): 9780198743583 Издательство: Oxford Academ Рейтинг: Цена: 5384.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This new edition of the Oxford Handbook of Medical Statistics provides doctors and medical students with a clear and concise explanation of statistical methods. It is an accessible and thorough account of a complex subject, and the previous edition has been described by readers as a `statistical Bible`.
Автор: Patrick Название: An Introduction to Medicinal Chemistry ISBN: 0199697396 ISBN-13(EAN): 9780199697397 Издательство: Oxford Academ Цена: 6176.00 р. Наличие на складе: Нет в наличии.
Описание: An Introduction to Medicinal Chemistry is the leading text for university courses on this subject. Renowned for being a textbook loved equally by both students and lecturers, it presents complete coverage in an accessible and engaging style. The text begins with the essential biochemistry on which an understanding of medicinal chemistry is built, introducing the structure and function of important drug targets. It then explores how drugs interact with the body and the consequences of those reactions. There is a section on general principles and strategies involved in discovering and designing new drugs, and another on useful 'tools of the trade'. The text ends with a contemporary look at specific topics within medicinal chemistry, for example, antiviral and anticancer agents; cholinergics and anticholinesterases; and antiulcer agents. Learning features throughout An Introduction to Medicinal Chemistry help to unlock this fascinating subject. A glossary helps to familiarise the language of medicinal chemistry. Boxes present in- depth material and explore how concepts are applied in practice. Key points summarise sections within chapters, providing a basis for revision, and questions at the end of chapters and on the accompanying Online Resource Centre allow the reader to test their understanding and develop molecular modelling skills.
Автор: Geoff Lawton Название: Progress in Medicinal Chemistry,55 ISBN: 044463715X ISBN-13(EAN): 9780444637154 Издательство: Elsevier Science Рейтинг: Цена: 23412.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
"Progress in Medicinal Chemistry" provides a review of eclectic developments in medicinal chemistry. This volume includes chapters covering recent advances in cancer therapeutics, "f"luorine in medicinal chemistry, a perspective on the next generation of antibacterial agents derived by manipulation of natural products, a new era for Chagas Disease drug discovery? and imaging in drug development. Extended timely reviews of topics in medicinal chemistryTargets and technologies relevant to the discovery of tomorrow s drugs.Analyses of successful drug discovery programmes"
This fourth volume in a four-volume set rounds out the set by offering new theories and applications for the diagnosis and treatment of physical disorders. Having laid the groundwork in the first three volumes, the authors now embark on significant, real-life scenarios that apply their philosophy to physical disorder treatments, after covering mental disorders in volume three. The goal of the project is to take the industry toward sustainability, not just in terms of the chemical engineering used to create medicines, but also environmentally, economically, and personally. Their unique approach uses a more holistic and philosophically cohesive method for treating mental disorders, making the industry "greener" and the patient healthier.
The four volumes in "The Greening of Pharmaceutical Engineering" are:
- Volume 1: Practice, Analysis, and Methodology
- Volume 2: Theories and Solutions
- Volume 3: Applications for Mental Disorder Treatments
- Volume 4: Applications for Physical Disorder Treatments
This ground-breaking set of books is a unique and state-of-the-art study that only appears here, within these pages. A fascinating study for the engineer, scientist, and pharmacist working in the pharmaceutical industry and interested in sustainability, it is also a valuable textbook for students and faculty studying these subjects.
Автор: Gert Fricker; Melanie Ott; Anne Mahringer Название: The Blood Brain Barrier (BBB) ISBN: 3662437864 ISBN-13(EAN): 9783662437865 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.
Автор: Peter H. Seeberger; Christoph Rademacher Название: Carbohydrates as Drugs ISBN: 331908674X ISBN-13(EAN): 9783319086743 Издательство: Springer Рейтинг: Цена: 36570.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Carbohydrate-Based Synthetic Chemistry in the Context of Drug Design.- Iminosugars: Therapeutic Applications and Synthetic Considerations.- Computational Docking as a Tool for the Rational Design of Carbohydrate-Based Drugs.- Discovery and Development of Selective Renal Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Dapagliflozin for the Treatment of Type 2 Diabetes.- Design, Synthesis, and Applications of Galectin Modulators in Human Health.- Discovery and Application of FimH Antagonists.- Carbohydrate-Based Anti-Virulence Compounds Against Chronic Pseudomonas aeruginosa Infections with a Focus on Small Molecules.- The Evolution of a Glycoconjugate Vaccinefor Candidaalbicans.
Автор: Qing-Ping Zeng Название: Artemisinin and Nitric Oxide ISBN: 3662476878 ISBN-13(EAN): 9783662476871 Издательство: Springer Рейтинг: Цена: 7685.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book discusses both the beneficial and harmful aspects of NO in biology and medicine, and also introduces the emerging discovery of artemisinin in antitumor, antibacterial infection, anti-inflammation, and antiaging contexts. In 1992 nitric oxide (NO) was voted “Molecule of the Year” by Science magazine, and the discovery of its physiological roles has led to Nobel Prize-winning work in neuroscience, physiology and immunology. The book explains why we should maintain a steady-state NO level that is derived from neuronal or epithelial NO synthase, and avoid the extremely high NO level resulting from inducible NO synthase. The book offers a valuable resource for medical chemists, clinicians, biologists and all those interested in health and disease.
Автор: Dietmar Krautwurst Название: Taste and Smell ISBN: 3319489259 ISBN-13(EAN): 9783319489254 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Taste receptor gene expression outside the gustatory system.- Medicinal Chemistry of Plant Naturals as Agonists/Antagonists for Taste Receptors.- Chemical activation of TRP channels in taste and smell.- Olfactory transduction channels and their modulation by varieties of volatile substances.- Chemosensory G protein-coupled receptors (GPCR) in blood leukocytes.- Neuronal functions and emerging pharmacology of TAAR1.
Описание: A comprehensive introduction to inorganic chemistry and, specifically, the science of metal-based drugs, Essentials of Inorganic Chemistry describes the basics of inorganic chemistry, including organometallic chemistry and radiochemistry, from a pharmaceutical perspective.
Описание: Intends to define the area of pharmaceutical chemistry as distinct from medicinal chemistry. This book emphasizes on the physicochemical properties of drug molecules and, in so far as they are known, the way that these properties govern the interaction of the drug with its target.
Описание: This book comprehensively describes the development and practice of DNA-encoded library synthesis technology.
Название: Handbook of Synthetic Antioxidants ISBN: 0367455854 ISBN-13(EAN): 9780367455859 Издательство: Taylor&Francis Рейтинг: Цена: 6736.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Emphasizes the efficacy of synthetically occurring compounds in the management of free radical-mediated illnesses. The text details the design, development and delivery of therapeutic antioxidants used in the treatment of pathophysiological disorders, from amylotrophic lateral sclerosis (ALS) and multiple sclerosis (MS) to Alzheimer`s disease.
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