Автор: Pecorino, Lauren Название: Molecular Biology of Cancer ISBN: 0198833024 ISBN-13(EAN): 9780198833024 Издательство: Oxford Academ Рейтинг: Цена: 11191.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers an accessible, engaging, and optimistic account of cancer biology for undergraduate and graduate students.
Автор: Pecorino Lauren Название: Molecular Biology of Cancer ISBN: 0198717342 ISBN-13(EAN): 9780198717348 Издательство: Oxford Academ Рейтинг: Цена: 7126.00 р. Наличие на складе: Поставка под заказ.
Описание: Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers the most engaging and accessible account of cancer biology that makes the link between our understanding of cancer and the development of new therapeutics crystal clear.
Автор: Daniele Focosi Название: Resistance to Tyrosine Kinase Inhibitors ISBN: 3319460900 ISBN-13(EAN): 9783319460901 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The volume will serve as a primer on tyrosine kinase signaling and its importance in cancer. The volume will first introduce the common denominators of small-molecule and antibody-derived inhibitors, as well as the general phenomenon of resistance. The volume will then detail resistance to the most commonly used classes of tyrosine kinase inhibitors, and will focus specific chapters on resistance to BCR-ABL1, FLT3, angiokinase family members, and ALK inhibitors.
Автор: Cristina Maccalli; Matilde Todaro; Soldano Ferrone Название: Cancer Stem Cell Resistance to Targeted Therapy ISBN: 3030166236 ISBN-13(EAN): 9783030166236 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book represents an up-dated summary of the state of the art of the characterization of cancer stem cell/ cancer initiating cell (CSC/CIC) properties. An overview of the definition and biological properties of CSCs/CICs as well as the role of these cells in determining the resistance to standard and immune-based therapies is provided. It also discusses limitations in the achievement of a definitive biological characterization of CSCs/CICs due to their high extent of plasticity and heterogeneity that is also mutually driven by the interaction of these cells with the tumor microenvironment. The limitations in targeting CSCs/CICs with immunotherapy are also explained together with explorative combination approaches that could increase the susceptibility of these cells to the recognition by immune cells. This book is conceived for a broad audience, including students, teachers, scientific experts. The critical revision of available results in terms of immunological profile of CSCs/CICs and the efficacy in targeting these cells by immunological approaches, results in a comprehensive and up to date recapitulation of the field and provides interesting suggestions on how to focus future investigations in order to assess the role of CSCs/CICs as prognostic and predictive biomarkers of responsiveness to therapies for cancer patients.
Автор: Maccalli Cristina, Todaro Matilde, Ferrone Soldano Название: Cancer Stem Cell Resistance to Targeted Therapy ISBN: 3030166260 ISBN-13(EAN): 9783030166267 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book represents an up-dated summary of the state of the art of the characterization of cancer stem cell/ cancer initiating cell (CSC/CIC) properties.
Автор: Benjamin Bonavida Название: Molecular Mechanisms of Tumor Cell Resistance to Chemotherapy ISBN: 1461470692 ISBN-13(EAN): 9781461470694 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book surveys current advances in understanding the mechanisms of cancer cell resistance to apoptotic stimuli, which eventually result in cancer progression and metastasis. Developments presented here may help improve clinical response to resistant tumors.
Автор: Benjamin Bonavida Название: Molecular Mechanisms of Tumor Cell Resistance to Chemotherapy ISBN: 1489988416 ISBN-13(EAN): 9781489988416 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book surveys current advances in understanding the mechanisms of cancer cell resistance to apoptotic stimuli, which eventually result in cancer progression and metastasis. Developments presented here may help improve clinical response to resistant tumors.
Описание: This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers.
Автор: Yanhong Shi; Dennis Clegg Название: Stem Cell Research and Therapeutics ISBN: 9048178940 ISBN-13(EAN): 9789048178940 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This updated reference covers current knowledge in stem cell research and integrates basic stem cell biology with regenerative medicine applications for many human diseases including cardiovascular diseases, neurological disorders and liver degeneration.
Автор: L. Harivardhan Reddy; Patrick Couvreur Название: Macromolecular Anticancer Therapeutics ISBN: 1461424925 ISBN-13(EAN): 9781461424925 Издательство: Springer Рейтинг: Цена: 36570.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book details the macromolecular therapeutics for cancer therapy. It also covers the classification of these anticancer drugs based on therapeutic targets and elaborates on different classes of anticancer therapeutics.
Автор: Amanda Tivnan Название: Resistance to Targeted Therapies Against Adult Brain Cancers ISBN: 331946504X ISBN-13(EAN): 9783319465043 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume will bring together a review of research being carried out by international experts in this field, detailing treatment and research approaches in several forms of malignant brain tumors. These include glioblastoma (GBM), a highly aggressive and fatal form of astrocytoma which accounts for 80% of newly diagnosed brain tumor patients per year, and meningioma, of which 10% are malignant and extremely resistant to targeted therapies. The volume will also include a discussion of methods to overcome blood-brain barrier exclusion for more efficient targeted drug delivery in all forms of brain cancer treatment. The volume will include information on the repurposing of drugs in an attempt to circumvent drug resistance, use of small molecule inhibitors in GBM treatment, mechanisms of secondary brain metastasis, drug resistance, and state-of-the-art imaging of targeted therapies.
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