Epigenetics, Development, Ecology and Evolution, Vaschetto
Автор: Ferguson, Bradley Название: Ferguson-NUTRITIONAL EPIGENOMICS ISBN: 0128168439 ISBN-13(EAN): 9780128168431 Издательство: Elsevier Science Рейтинг: Цена: 26444.00 р. Наличие на складе: Поставка под заказ.
Описание:
Nutritional Epigenomics offers a comprehensive overview of nutritional epigenomics as a mode of study, along with nutrition's role in the epigenomic regulation of disease, health and developmental processes. Here, an expert team of international contributors introduces readers to nutritional epigenomic regulators of gene expression, our diet's role in epigenomic regulation of disease and disease inheritance, caloric restriction and exercise as they relate to recent epigenomic findings, and the influence of nutritional epigenomics over circadian rhythms, aging and longevity, and fetal health and development, among other processes. Disease specific chapters address metabolic disease (obesity and diabetes), cancer, and neurodegeneration, among other disorders.
Diet-gut microbiome interactions in the epigenomic regulation of disease are also discussed, as is the role of micronutrients and milk miRNAs in epigenetic regulation. Finally, chapter authors examine ongoing discussions of race and ethnicity in the social-epigenomic regulation of health and disease.
Empowers the reader to employ nutritional epigenomics approaches in their own research
Discusses the latest topics in nutritional epigenomics in the regulation of aging, circadian rhythm, inheritance and fetal development, as well as metabolism and disease
Offers a full grounding in epigenetic reprogramming and nutritional intervention in the treatment and prevention of disease, as informed by population-based studies
Автор: Francis Richard C. Название: Epigenetics: How Environment Shapes Our Genes ISBN: 039334228X ISBN-13(EAN): 9780393342284 Издательство: Wiley Рейтинг: Цена: 2058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Goodbye, genetic blueprint. . . . The first book for general readers on the game-changing field of epigenetics.
Автор: Vaschetto Название: Epigenetics, Development, Ecology and Evolution ISBN: 3031137701 ISBN-13(EAN): 9783031137709 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Epigenetic modifications comprise heritable gene expression changes that occur without alteration of the DNA sequence and 'co-act' with genetic factors to shape development processes and evolutionary trajectories. Multicellular organisms receive different types of environmental stimuli/stresses that trigger epigenetic modifications during development. These environmentally driven mechanisms represent an underlying cause of phenotypic diversity, especially in metazoans. This book aims to present some of the latest epigenetic insights into the development of metazoans (including humans) as an intersection between their ecology and evolution.
Автор: Moskalev, Alexey Название: Epigenetics of Aging and Longevity ISBN: 0128110600 ISBN-13(EAN): 9780128110607 Издательство: Elsevier Science Рейтинг: Цена: 19875.00 р. Наличие на складе: Поставка под заказ.
Описание:
Epigenetics of Aging and Longevity provides an in-depth analysis of the epigenetic nature of aging and the role of epigenetic factors in mediating the link between early-life experiences and life-course health and aging. Chapters from leading international contributors explore the effect of adverse conditions in early-life that may result in disrupted epigenetic pathways, as well as the potential to correct these disrupted pathways via targeted therapeutic interventions. Intergenerational epigenetic inheritance, epigenetic drug discovery, and the role of epigenetic mechanisms in regulating specific age-associated illnesses--including cancer and cardiovascular, metabolic, and neurodegenerative diseases--are explored in detail.
This book will help researchers in genomic medicine, epigenetics, and biogerontology better understand the epigenetic determinants of aging and longevity, and ultimately aid in developing therapeutics to extend the human life-span and treat age-related disease.
Автор: Oldroyd, Benjamin Название: Beyond dna ISBN: 0522878865 ISBN-13(EAN): 9780522878868 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 1880.00 р. Наличие на складе: Нет в наличии.
Описание: Beyond DNA is a journey through uncharted territory, advancing new ways of thinking about evolution and adaptation. For nearly a hundred years evolutionary biologists have understood that evolution proceeds by substituting better genes for less good ones. But consensus is growing that this is not the whole story: geneticists are now revealing that spores, sperm, pollen and ova are packed with personalised genetic information that plays an important role in offspring development and has lifelong effects. This epigenetic - or 'extra-genetic '- inheritance therefore makes significant contributions to evolutionary processes. In this highly accessible book, packed with instructive examples, Benjamin Oldroyd explains how a greater appreciation of the role of epigenetics is helping to solve a multitude of previously intractable problems in evolutionary biology - puzzles as varied as why invasive plants and animals can rapidly adapt to changes in their environment, how worker bees and queen bees can develop from the same egg, and why cancer becomes more common as we age. Beyond DNA concisely explains the mechanisms that underlie epigenetics, shows how epigenetic processes can lead to adaptation, and speculates on meaty issues such as the role that epigenetics plays in human health and happiness.
Автор: Trygve Tollefsbol Название: Medical Epigenetics ISBN: 0128032391 ISBN-13(EAN): 9780128032398 Издательство: Elsevier Science Рейтинг: Цена: 22696.00 р. Наличие на складе: Поставка под заказ.
Описание: "
Medical Epigenetics" is an inclusive volume on the medical aspects of epigenetics with a focus on human systems, epigenetic disease that affect these systems, and modes of treating epigenetic-based disorders and diseases. This book provides stand-alone coverage of all human systems relevant to epigenetic maladies and all major aspects of medical epigenetics. It is useful not only to physicians, nurses, medical students, and many others directly involved with healthcare, but also investigators in life sciences, biotech companies, graduate students, and all others who are interested in more applied aspects of epigenetics.
The expansion of the field of epigenetics has brought a wealth of information with respect to variations in phenotypes that are heritable. In addition, many advances have emerged that have shown epigenetic aberrations as central to a number of diseases and disorders that were previously thought to be manifested primarily through genetic factors. Along with the remarkable studies that have been made in our understanding of epigenetic-based diseases and disorders has come new information that allows treatments that target these many epigenetic aberrations. "Medical Epigenetics" brings all of this knowledge together to comprehensively review the state of medical epigenetics in one defining volume.
The basic design of "Medical Epigenetics" is to lead the reader from the fundamental mechanisms of epigenetics as they apply to humans through approaches for treating epigenetic-based diseases. This book begins with the basic tenets of epigenetics in human systems and progresses through general medical aspects of epigenetics, epigenetics or system disorders, multi-system medical epigenetics, pharmacology of epigenetics, and therapeutic epigenetics. "Medical Epigenetics" closes with a chapter on future prospects in medical epigenetics. This book is by far the most complete book in the area of applied epigenetics. Focuses on practical and applied aspects of medical epigeneticsIncludes peer-reviewed chapters with up-to-date coverage of emerging topics in medical epigenetics by leading expertsAppeals to those interested in fundamental epigenetics and inheritance, as well as those with more clinical interests including practicing physicians and other health care professionalsCovers the basic tenets of epigenetics in human systems and progresses through general medical aspects of epigenetics, epigenetics or system disorders, multi-system medical epigenetics, pharmacology of epigenetics, and therapeutic epigenetics
You Are About To Develop A Comprehensive Understanding Of The Concept Of Epigenetics, Its Place In Modern Day Medicine, And Health Optimization And Why It Is Literally Changing How We Approach The Treatment Of Various Health Problems
Here is a bit of what you'll learn from this 2 in 1 book:
- What epigenetics are, why they're important and how they work
- How epigenetics relate with our experiences
- How cells divide, and how genes control the growth and division of cells
- The difference between the DNA, gene and chromosomes
- The existing evidence of epigenetic changes, including in transgenerational epigenetic inheritance
- The ins and outs of epigenetics mechanisms
- The types of epigenetic therapies available today, including their risks, benefits and research on them
- The effect of epigenetic control in transcriptional regulation in pluripotency and early differentiation, DNA methylation and Demethylation, nucleosome remodeling and chromatin looping
- How epigenetics work at the molecular level and the effect of DNA damage in epigenetic change
- The functions of epigenetics, and how they boost mindfulness training, healthy eating and exercise
- How epigenetic therapy and modifications affects diabetic retinopathy, emotional disorders, cardiac dysfunction, cancer and schizophrenia, mesothelioma and many more
- How epigenetic modifications are used in understanding plant and animal evolution
- How epigenetic mechanisms are used in understanding human adaptation, boosting memory formation, growth and reinforcing infant neurobehavior.
- The role of epigenetic mechanisms in maternal care
- The role of environmental chemicals in epigenetics
- How epigenetics are involved in neurodegenerative diseases, drug formation, human development, the development of Hox genes and many more.
- The role of environmental exposures in pathophysiology of IPF
- Modulation of epigenetic marks by environmental exposures
- How epigenetic regulation affects the immune system
...And so much more
Whether you are a beginner or an intermediate in epigenetics, you will find this book educative, as you learn the A-Z of factors that are quickly changing our understanding of the structure of life.
Don't wait....
Автор: Pandey, Rajesh Название: Rna-Based Regulation In Human Health And Disease,16 ISBN: 0128171936 ISBN-13(EAN): 9780128171936 Издательство: Elsevier Science Рейтинг: Цена: 26444.00 р. Наличие на складе: Поставка под заказ.
Описание:
RNA-based Regulation in Human Health and Disease offers an in-depth exploration of RNA mediated genome regulation at different hierarchies. Beginning with multitude of canonical and non-canonical RNA populations, especially noncoding RNA in human physiology and evolution, further sections examine the various classes of RNAs (from small to large noncoding and extracellular RNAs), functional categories of RNA regulation (RNA-binding proteins, alternative splicing, RNA editing, antisense transcripts and RNA G-quadruplexes), dynamic aspects of RNA regulation modulating physiological homeostasis (aging), role of RNA beyond humans, tools and technologies for RNA research (wet lab and computational) and future prospects for RNA-based diagnostics and therapeutics. One of the core strengths of the book includes spectrum of disease-specific chapters from experts in the field highlighting RNA-based regulation in metabolic & neurodegenerative disorders, cancer, inflammatory disease, viral and bacterial infections. We hope the book helps researchers, students and clinicians appreciate the role of RNA-based regulation in genome regulation, aiding the development of useful biomarkers for prognosis, diagnosis, and novel RNA-based therapeutics.
Автор: Cheryl Natividad Название: Epigenetics: Beyond Genetics ISBN: 1774690675 ISBN-13(EAN): 9781774690673 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 25502.00 р. Наличие на складе: Нет в наличии.
Описание: DNA is touted as containing the blueprint of life. Therefore, changes in the blueprint will have an impact on the living organism. While this has been proven to be usually true, it has also been established that heritable changes in gene function can occur even if the DNA remains unchanged. Epigenetics: Beyond Genetics introduces the field of epigenetics that aims to understand the mechanisms, outside the DNA sequence, that influence gene function and regulation and the various factors that affect these mechanisms. It provides an in-depth look at how two of the epigenetic mechanisms, namely DNA methylation and histone modification, are at work, especially in the human or mammalian milieu.
Описание: This timely book critically examines the capabilities and limitations of new areas of biology, especially epigenetics and neuroscience, that are used as powerful arguments for developing social policy in a particular direction, exploring their implications for policy and practice.
Автор: Burdge Graham, Lillycrop Karen Название: Nutrition, Epigenetics and Health ISBN: 9813143304 ISBN-13(EAN): 9789813143302 Издательство: World Scientific Publishing Цена: 13781.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Epigenetics is emerging as an important factor in risk of diseases of global importance including obesity, cardiovascular disease and cancer. Unlike gene polymorphisms which have been the focus of understanding the role of inherited disease susceptibility for some time, epigenetic can be modified by environmental factors, in particular nutrition. Thus research into the role of epigenetics in disease has substantial potential for explaining the impact of the environmental factors such as diet on disease risk. Since epigenetic processes can be modified by nutrition, it may be possible to modify inappropriate epigenetic marks by nutritional interventions to reduce disease risk. This book will explore current understanding of the interaction between nutrition, epigenetics and disease risk, will place this knowledge in the context of global health and discuss the ethical implications of this research.
Автор: Kalkan Название: Cancer Epigenetics ISBN: 303142364X ISBN-13(EAN): 9783031423642 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Epigenetic alterations are heritable changes that play a key role in human development and tissue-specific gene expression patterns. These changes can lead to alterations involved in tumor formation, imprinting, and metabolic disorders. Recent advances can help us understand the importance of epigenetic changes in both cancer development and tumor progression. In addition, epigenetic alterations may also be useful diagnostic and prognostic markers for the analysis of tumor progression. Split into two parts, the book opens with a comprehensive overview of the identification and analysis of epigenetic changes in cancer and the consequences of such changes during tumor development. The second part focusses on cancer specific epigenetic alterations and discusses the potential use of epigenetic markers as biomarkers in diagnosis, early cancer progression, and prognosis. Moreover, it reviews the therapeutic potential of epigenetic drugs. Given its scope, Cancer Epigenetics is an indispensable resource not only for researchers working in the field of human epigenetics and cancer research but also for advanced students seeking for an introduction into epigenetic mechanisms.
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