Автор: John F. Atkins; Raymond F. Gesteland Название: Recoding: Expansion of Decoding Rules Enriches Gene Expression ISBN: 146142531X ISBN-13(EAN): 9781461425311 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Knowledge of recoding is essential for understanding the organization and expression of genes in viruses and all organisms. This volume details specific recoding examples to assist the reader with understanding the mechanisms and the mRNA signals.
Описание: This book explores the major cytokines, such as IL-1 and IFN-?, with respect to the regulation of their gene expression and protein production in specific immune cell types. It discusses both healthy physiological settings and in pathological situations in which the expression of some cytokines could be dysregulated, resulting in either immunodeficiency or exacerbated inflammatory sequelae in animal models as well as in human patients. Cytokines are important regulators of immune responses that require the highly coordinated participation and communication of multiple cell types. The expression of cytokines by various producer cell types is therefore carefully regulated in response to environmental cues at multiple levels: transcription, translation and posttranslational modification. Presenting cutting-edge advances in our understanding of the regulation of cytokine expression, this book is a valuable resource for anyone involved or interested in immune regulation.
Автор: Rodrick Wallace; Deborah Wallace Название: Gene Expression and Its Discontents ISBN: 3319480774 ISBN-13(EAN): 9783319480770 Издательство: Springer Рейтинг: Цена: 21661.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book describes how epigenetic context, in a large sense, affects gene expression and the development of an organism, using the asymptotic limit theorems of information theory to construct statistical models useful in data analysis. The approach allows deep understanding of how embedding context affects development. We find that epigenetic information sources act as tunable catalysts, directing ontogeny into characteristic pathways, a perspective having important implications for epigenetic epidemiology. In sum, environmental stressors can induce a broad spectrum of developmental dysfunctions, and the book explores a number of pandemic chronic diseases, using U.S. data at different scales and levels of organization. In particular, we find the legacy of slavery has been grossly compounded by accelerating industrial decline and urban decay. Individual chapters are dedicated to obesity and its sequelae, coronary heart disease, cancer, mental disorders, autoimmune dysfunction, Alzheimer’s disease, and other conditions. Developmental disorders are driven by environmental factors channeled by historical trajectory and are unlikely to respond to medical interventions at the population level in the face of persistent individual and community stress. Drugs powerful enough to affect deleterious epigenetic programming will likely have side effects leading to shortened lifespan. Addressing chronic conditions and developmental disorders requires significant large-scale changes in public policy and resource allocation.
Автор: Johnston, James Fauber, Terri L. Название: Essentials of Radiographic Physics and Imaging ISBN: 0323339662 ISBN-13(EAN): 9780323339667 Издательство: Elsevier Science Рейтинг: Цена: 15915.00 р. Наличие на складе: Поставка под заказ.
Описание:
Written by radiographers for radiographers, Essentials of Radiographic Physics and Imaging, 2nd Edition follows the ASRT recommended curriculum and focuses on what the radiographer needs to understand to safely and competently perform radiographic examinations. This comprehensive radiologic physics and imaging text links the two subjects together so that you understand how they relate to each other - and to clinical practice. Prepare for success on the ARRT exam and the job with just the right amount of information on radiation production and characteristics, imaging equipment, film screen image acquisition and processing, digital image acquisition and display, image analysis, and the basic principles of computed tomography.
345 photos and line drawings
encourage you to visualize important concepts.
Strong pedagogy, including chapter objectives, key terms, outlines, bulleted chapter summaries, and specialty boxes, help you organize information and focus on what is most important in each chapter.
Make the Physics Connection and Make the Imaging Connection boxes link physics and imaging concepts so you fully appreciate the importance of both subjects.
Educator resources on Evolve, including lesson plans, an image collection, PowerPointpresentations, and a test bank, provide additional resources for instructors to teach the topics presented in the text.
Theory to Practice boxes succinctly explain the application of concepts and describe how to use the information in clinical practice.
Critical Concept boxes further explain and emphasize key points in the chapters.
Math Application boxes use examples to show how mathematical concepts and formulas are applied in the clinical setting.
An emphasis on the practical information highlights just what you need to know to ace the ARRT exam and become a competent practitioner.
Numerous critique exercises teach you how to evaluate the quality of radiographic images and determine which factors produce poor images.
A glossary of key terms serves as a handy reference.
NEW Updated content reflects the newest curriculum standards outlined by the ARRT and ASRT
, providing you with the information you need to pass the boards.
NEW Critical Thinking Questions at the end of every chapter offer opportunity for review and greater challenge.
NEW Chapter Review Questions at the end of every chapter allow you to evaluate how well you have mastered the material in each chapter.
NEW Increased coverage of radiation protection principles helps you understand the ethical obligations to minimize radiation dosages, shielding, time and distance, how to limit the field of exposure and what that does to minimize dose, and technical factors and how they represent the quantity and quality of radiation.
NEW Conversion examples and sample math problems give you the practice needed to understand complex concepts.
NEW More images highlighting key concepts help you visualize the material.
NEW Expansion of digital image coverage and ample discussion on differentiating between digital and film ensures you are prepared to succeed on your exams.
NEW All-new section on manual vs. AEC use in Chapter 13 keeps you in the know.
NEW and UPDATED Expanded digital fluoroscopy section, including up-to-date information on LCD and Plasma displays, familiarizes you with the equipment you will encounter.
NEW Online chapter quizzes on Evolve feature 5-10 questions each and reinforce key concepts.
NEW PowerPoint presentations with new lecture notes on Evolve and in-depth information in the notes section of ea
Автор: Spyros Papageorgiou Название: HOX Gene Expression ISBN: 1441923977 ISBN-13(EAN): 9781441923974 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Hox Gene Expression starts with the amazing discovery of the homeobox twenty-three years ago and follows the exciting path thereafter of a series of breakthroughs in Genetics, Development and Evolution. Researchers and graduate students in biology and medicine will benefit from this integrated overview of Hox gene activities.
Описание: This volume describes a variety of protocols that will allow the readers to study different aspects of transcriptional and posttranscriptional gene expression regulation in eukaryotic cells. Chapters focus on the latest use of CRISPRi and RNAi technologies for studying various aspects of transcriptional and posttranscriptional regulation and tools to navigate protocols on key bioinformatics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfallsAuthoritative and cutting-edge, Eukaryotic Transcription and Post-Transcription Gene Expression Regulation aims to ensure successful results in the further study of this vital field.
Автор: Edward J. Murray Название: Gene Transfer and Expression Protocols ISBN: 1489944036 ISBN-13(EAN): 9781489944030 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Biology is the study of living things. The classical approach might be described as holistic and descriptive, whereas the modern molecular - proach aims to be investigative, reductionist, and mechanistic . Genes contain all the information for the structure of all living things ; thus, the understanding of how genes are regulated is an important step toward understanding the nature of living things. The study of gene regulation has been made more tractable by the design of simple expe- mental models in which a single gene can be isolated from the milieu of the organism. The new science of molecular biology has introduced techniques that permit the design of such experimental models. In - sence, the genome of the organism is dissected in such a manner that specific genes may now be introduced into an appropriate cell line . Subsequent analysis of the proteins expressed from the genes under study results in the identification of the regulatory DNA sequences .
Автор: Rodrick Wallace; Deborah Wallace Название: Gene Expression and Its Discontents ISBN: 148998531X ISBN-13(EAN): 9781489985316 Издательство: Springer Рейтинг: Цена: 30606.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume examines a class of probability models describing how epigenetic context affects gene expression and organismal development, using the asymptotic limit theorems of information theory in a highly formal manner.
Автор: Gary H. Perdew; Jack P. Vanden Heuvel; Jeffrey M. Название: Regulation of Gene Expression ISBN: 1627038086 ISBN-13(EAN): 9781627038089 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The use of molecular biology and biochemistry to study the regulation of gene expression has become a major feature of research in the biological sciences. Many excellent books and reviews exist that examine the experimental methodology employed in specific areas of molecular biology and regulation of gene expression. However, we have noticed a lack of books, especially textbooks, that provide an overview of the rationale and general experimental approaches used to examine chemically or disease-mediated alterations in gene expression in mammalian systems. For example, it has been difficult to find appropriate texts that examine specific experimental goals, such as proving that an increased level of mRNA for a given gene is attributable to an increase in transcription rates. Regulation of Gene Expression: Molecular Mechanisms is intended to serve as either a textbook for graduate students or as a basic reference for laboratory personnel. Indeed, we are using this book to teach a graduate-level class at The Pennsylvania State University. For more details about this class, please visit http://moltox. cas. psu. edu and select “Courses. ” The goal for our work is to provide an overview of the various methods and approaches to characterize possible mechanisms of gene regulation. Further, we have attempted to provide a framework for students to develop an understanding of how to determine the various mechanisms that lead to altered activity of a specific protein within a cell.
Автор: Lorraine O`Driscoll Название: Gene Expression Profiling ISBN: 149396173X ISBN-13(EAN): 9781493961733 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this book, experts present a broad range of available and developing techniques for the analysis of gene expression at the DNA, RNA, and protein levels. A collection of clearly described and illustrated chapters includes tips and implementation advice.
Автор: Argelia Lorence Название: Recombinant Gene Expression ISBN: 1493962213 ISBN-13(EAN): 9781493962211 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Recombinant gene expression research has brought new advances such as the birth of the `omics` technologies. Here, expert researchers detail many RGE methods now used, including those for bacteria, fungi, plants and plant cells, and animals and animal cells.
Автор: Thomas C. Evans, Jr.; Ming-Qun Xu Название: Heterologous Gene Expression in E.coli ISBN: 1493957252 ISBN-13(EAN): 9781493957255 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Practical and cutting-edge, Heterologous Gene Expression in E. coli: Methods and Protocols seeks to familiarize the researcher with the myriad of E. coli expression strains available and move E. coli closer to that ideal of the perfect host.
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