Computational Modeling of Drugs Against Alzheimer`s Disease, Kunal Roy
Автор: Rudolph Название: Alzheimer`s Disease ISBN: 1439827087 ISBN-13(EAN): 9781439827086 Издательство: Taylor&Francis Рейтинг: Цена: 17149.00 р. 24499.00-30% Наличие на складе: Есть (1 шт.) Описание:
In recent years, a tremendous amount of effort has been focused on better understanding the fundamentals of Alzheimer's disease (AD) to facilitate early and accurate diagnosis and appropriately targeted therapeutic treatments. Alzheimer's Disease: Targets for New Clinical, Diagnostic, and Therapeutic Strategies provides a detailed synopsis of the current state of the art of diagnostics and therapeutics and identifies emerging technologies and molecules that show promise in the management and treatment of AD.
With contributions from experts drawn from academia, clinical practice, and the biotechnology and pharmaceutical industries, the book explores:
The basis of AD and the role of Aβ oligomers in development of disease
Existing and emerging in vitro biomarker-based methodologies for the diagnosis of AD, focusing on genetic, biochemical, and conformational strategies
In vivo imaging diagnostic approaches
Evolving diagnostic criteria, health regulatory guidelines, biomarkers in clinical trials, and available and emerging therapies
Recent progress in small-molecule disease-modifier drug discovery efforts for AD, specifically in the areas of Aβ, tau, and emerging neuroprotective/neurorepair approaches
How a case study of AD raises issues regarding clinical and pathologic criteria, risk factors, and the amyloid hypothesis
The molecular conformational factors that govern the pathogenicity of aggregating proteins, and how these factors could represent new targets for disease-modifying therapies
The latest epidemiological, pathological, biochemical, and behavioral studies that may shed some light on the risk of developing AD and similar dementias after traumatic brain injury
Examining current hypotheses and suggesting possible new approaches to therapeutic clinical applications, this volume paves the way for a robust pipeline of therapeutics to combat not only AD, but a whole host of other neurodegenerative diseases.
Автор: Yoshikuni Mizuno; Abraham Fisher; Israel Hanin Название: Mapping the Progress of Alzheimer`s and Parkinson`s Disease ISBN: 1475709730 ISBN-13(EAN): 9781475709735 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: 1h The 5 International Conference on the Progress in Alzheimer`s Disease and Parkinson`s 51 1 Disease took place from March 31 to April 5 \ 2001 in Kroto, Japan. This international 1 conference was organized as a joint Congress with the 9 International Catecholamine Symposium.
Автор: Bradley T. Hyman; Charles Duyckaerts Название: Connections, Cognition and Alzheimer`s Disease ISBN: 3642645046 ISBN-13(EAN): 9783642645044 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Verna Benner Carson; Katherine Johnson Vanderhorst Название: Care Giving for Alzheimer`s Disease ISBN: 1493945270 ISBN-13(EAN): 9781493945276 Издательство: Springer Рейтинг: Цена: 8384.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Veteran clinicians offer a unique framework for understanding the psychological origins of behaviors typical of Alzheimer's and other dementias, and for providing appropriate care for patients as they decline. Guidelines are rooted in the theory of retrogenesis in dementia--that those with the condition regress in stages toward infancy--as well as knowledge of associated brain damage. The objective is to meet patients where they are developmentally to best be able to address the tasks of their daily lives, from eating and toileting to preventing falls and wandering. This accessible information gives readers a platform for creating strategies that are respectful, sensitive, and tailored to individual needs, thus avoiding problems that result when care is ineffective or counterproductive. Featured in the coverage: * Abilities and disabilities during the different stages of Alzheimer's disease. * Strategies for keeping the patient's finances safe. * Pain in those with dementia, and why it is frequently ignored. * "Help! I've lost my mother and can't find her!" * Sexuality and intimacy in persons with dementia. * Instructive vignettes of successful caring interventions. Given the projected numbers of individuals expected to develop dementing conditions, Care Giving for Alzheimer’s Disease will find immediate interest among clinical psychologists, health psychologists, psychiatrists, social workers, and primary care physicians.
Автор: Budson Название: The Handbook of Alzheimer`s Disease and Other Dementias ISBN: 1118672852 ISBN-13(EAN): 9781118672853 Издательство: Wiley Рейтинг: Цена: 4744.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This is a broad-ranging review of the current research on Alzheimer`s disease and other dementias from both basic neuroscience and clinical perspectives. It provides scientists and medical professionals with an extensive introduction and an up-to-date review of cutting-edge scientific advances in a single volume.
Описание: Due to rapidly aging populations, the number of people worldwide experiencing dementia is increasing, and the projections are grim. Despite billions of dollars invested in medical research, no effective treatment has been discovered for Alzheimer`s disease, the most common form of dementia. The Alzheimer Conundrum exposes the predicaments embedded
Автор: Davis Название: Alzheimer Talk, Text and Context ISBN: 1403935327 ISBN-13(EAN): 9781403935328 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This collection augments clinical inventories of Alzheimer`s studies with an emphasis on the ways caregivers and researchers can focus on communication enhancement and person-centered care. The contributors examine discourse boundaries and social relationships, gender-cued interaction and life-course analysis, online text by and about Alzheimer`s
Описание: Proceedings of the Second International Conference held in Kyoto, Japan, November 6-10, 1989
Автор: Martina Zimmermann Название: The Poetics and Politics of Alzheimer`s Disease Life-Writing ISBN: 3319443879 ISBN-13(EAN): 9783319443874 Издательство: Springer Рейтинг: Цена: 3913.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: and second, committed alleviation of caregiver burden through social support systems and altered healthcare policies requires significantly altered views about aging, dementia, and Alzheimer`s patients.
Описание: Cerebral amyloid angiopathy (CAA) is a distinctive abnormality of small cerebral blood vessels, one that has intrigued neuroscientists for decades.
Автор: G?rard Emilien; C?cile Durlach; Kenneth L. Minaker Название: Alzheimer Disease ISBN: 3034895917 ISBN-13(EAN): 9783034895910 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Alzheimer disease (AD) has become the most common form of dementia in industrialized countries and represents an increasing burden at the economic, social and medical level.
Автор: Christian Alzheimer Название: Molecular and Cellular Biology of Neuroprotection in the CNS ISBN: 1461349346 ISBN-13(EAN): 9781461349341 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Given the very limited capacity of regeneration in the brain, protecting neurons that are on the brink of death is a major challenge for basic and clinical neuroscience, with implications for a broad spectrum of acute and chronic neurological and psychiatric diseases.
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