Автор: Ribatti Название: History of Research on Tumor Angiogenesis ISBN: 9048181569 ISBN-13(EAN): 9789048181568 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In 1971, J. Folkman hypothesized that tumor growth is angiogenesis-dependent. In 2004, the FDA approved the first angiogenesis inhibitor. This book compiles the relevant literature of that history and emphasizes the antiangiogenic approach to treat tumors.
5. Therapeutic strategies, the concept of "normalization" and the role of VEGF inhibition
Index
Автор: Ribatti Название: Tumor Angiogenesis Assays ISBN: 1493939971 ISBN-13(EAN): 9781493939978 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume aims to provide a range of methods and protocols for studying tumor angiogenesis in vitro and in vivo to reflect advances in the field. The chapters in this book cover topics such as: morphological aspects of tumor angiogenesis, aortic ring assay and its use for the study of tumor angiogenesis, ex vivo tissue culture model for anti-angiogenic drug testing, transgenic zebrafish, orthotopic models of ovarian cancer, and uncovering metabolic effects of anti-angiogenic therapy in tumors by induced metabolic bioluminescence imaging. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting edge and thorough, Tumor Angiogenesis Assays: Methods and Protocols is a valuable resource for anyone interested in tumor angiogenesis assay research.
Описание: This book reviews and discusses knowledge gathered on Metabolic Syndrome and analyzes the interplay between oxidative stress, chronic inflammation and angiogenesis features. It focuses on recent discoveries and progress toward possible therapeutic strategies.
Автор: Shaker A. Mousa; Paul J. Davis Название: Angiogenesis Modulations in Health and Disease ISBN: 9400764669 ISBN-13(EAN): 9789400764668 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book offers in-depth explanations of pro-angiogenesis and anti-angiogenesis targets and their evaluation methods. Coverage includes preclinical and clinical methods and models, investigational status, and clinical applications.
Автор: Steiner; Weisz; Langer Название: Angiogenesis ISBN: 3034870035 ISBN-13(EAN): 9783034870030 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Exploring the critical role of angiogenesis in tumor progression and metastasis, this book features the latest and most promising anti-angiogenesis molecules now being deployed in the battle against hematological malignancies such as leukemia and lymphoma.
Автор: Reza Forough Название: New Frontiers in Angiogenesis ISBN: 9401782296 ISBN-13(EAN): 9789401782296 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
New Frontiers in Angiogenesis is a fresh and unconventional look at the field of angiogenesis. It focuses on provocative and cutting-edge topics in the field of angiogenesis. Each chapter will take the reader along on a journey into uncharted territories of angiogenesis. The volume starts with a comprehensive overview of the field and continues with topics that have been minimally explored. The topics deal with dynamics of vasculogenesis using imaging techniques, bone marrow-derived endothelial cell precursors as potential therapeutic tools, regulation of post-angiogenic vessel regression, vascular mimicry, design and construction of artificial vessels, bioengineering of angiogenesis, and lymphangiogenesis recapitulating angiogenesis in health and disease states. Each chapter is written by leading experts of the subjects. It is hoped that this volume will challenge all of us interested in the field of angiogenesis and cardiovascular biology, in particular those in academia and industries, to think "outside the box" and explore angiogenesis from a fresh angle. It is hoped that New Frontiers in Angiogenesis is thought provoking and serve as a road map for discovering new findings to help betterments of human health.
Автор: Jean-Jacques Feige; Gilles Pag?s; Fabrice Soncin Название: Molecular Mechanisms of Angiogenesis ISBN: 2817805623 ISBN-13(EAN): 9782817805627 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Angiogenesis is a multi-stage process that drives the generation of new blood and lymphatic vessels from pre-existing ones. It is highly active during embryogenesis, largely inactive during adulthood but reactivated during wound healing and under a number of pathological conditions including cancer and ocular diseases. In addition to endothelial cells, which line the walls of the vessels, several other cell types (pericytes, macrophages, progenitor cells…) also contribute to angiogenesis. A number of signaling pathways are activated and very finely tune the delicate morphogenetic events that ultimately lead to the formation of stable blood proof neovessels. This book reviews recent advances in our understanding of the molecular and cellular mechanisms of angiogenesis, with a focus on how to integrate these observations into the context of developmental, post-natal and pathological neovascularization. The book was published under the auspices of the French Angiogenesis Society. Most contributors are prominent members of this Society or international researchers who have actively contributed to the Annual Meetings of the Society.
Автор: Michael E. Maragoudakis Название: Molecular, Cellular, and Clinical Aspects of Angiogenesis ISBN: 1461380308 ISBN-13(EAN): 9781461380306 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of a NATO ASI held in Porto Carras, Halkidiki, Greece, June 16-27, 1995.
Автор: Ali Salajegheh Название: Angiogenesis in Health, Disease and Malignancy ISBN: 3319281380 ISBN-13(EAN): 9783319281384 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This book is about "Angiogenesis". A process in which new vasculature is formed from pre-existing capillaries. Angiogenesis process is associated with the proliferation and growth of both physiologically normal and neoplastic tissues, through the formation of vascular supply, essential for delivering growth requirements such as oxygen and nutrients.
The book describes more than 100 genes and their key regulatory functions in the context of normal healthy condition, disease and malignancy, cancer proliferation and progression. New insights into the role of angiogenesis and the therapeutic inhibition of its regulators are investigated, due to the great potential for exploitation in the development of a novel treatment for cancer.
New scientists, junior researchers and biomedical science students will find this book an invaluable introductory reference to their insight about angiogenesis and angiogenic role of more than 100 angiogenes and their role in healthy, disease and malignant conditions.
Автор: Dieter Marm?; Norbert Fusenig Название: Tumor Angiogenesis ISBN: 3662517981 ISBN-13(EAN): 9783662517987 Издательство: Springer Рейтинг: Цена: 50172.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With contributions by numerous experts
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