Автор: Ribatti Название: History of Research on Tumor Angiogenesis ISBN: 9048181569 ISBN-13(EAN): 9789048181568 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In 1971, J. Folkman hypothesized that tumor growth is angiogenesis-dependent. In 2004, the FDA approved the first angiogenesis inhibitor. This book compiles the relevant literature of that history and emphasizes the antiangiogenic approach to treat tumors.
Автор: Jawahar L. Mehta; Pankaj Mathur; Naranjan S. Dhall Название: Biochemical Basis and Therapeutic Implications of Angiogenesis ISBN: 3319611143 ISBN-13(EAN): 9783319611143 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Leading authorities on the biochemistry of this complex physiological process explain its critical role in human growth and development as well as the pathogenesis of cancer, heart disease, and other morbidities. The book fully updates the current literature.
Автор: Matthias Kirsch; Peter McL. Black Название: Angiogenesis in Brain Tumors ISBN: 1461346991 ISBN-13(EAN): 9781461346999 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: - Volume is divided into four sections, allowing easy navagation for researchers and practicing physicians- Text includes clinical trials- Written by leaders in the field
Автор: Steiner; Weisz; Langer Название: Angiogenesis ISBN: 3034870035 ISBN-13(EAN): 9783034870030 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Mark Slevin Название: Therapeutic Angiogenesis for Vascular Diseases ISBN: 9400789793 ISBN-13(EAN): 9789400789791 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Angiogenesis is the growth of new blood vessels and is a key process which occurs during pathological disease progression. Excessive and damaging angiogenesis occurs in diseases such as cancer, diabetic retinopathies, age-related macular degeneration and atherosclerosis. In other diseases such as stroke and myocardial infarction, insufficient or improper angiogenesis results in tissue loss and ultimately higher morbidity and mortality. In this book we will begin by providing the reader with an overview of the process of angiogenesis including normal embryological development of blood vessels. The following chapters will each focus on a key angiogenic disease incorporating current scientific knowledge concerning the causes of activation of the “angiogenic switch”, pathological consequences, current treatment options and future perspectives. Where appropriate, results from pre-clinical trials, novel imaging modalities and nanotechnological approaches will be incorporated into these sections. Finally, since it is now believed that the process of angiogenesis operated via different signalling mechanisms in different vascular beds, we will discuss our current understanding of this phenomenon. The target audience for this book would include researchers in all the basic sciences; post-graduate students at Universities and Institutes; pharmaceutical industries; clinicians working in vascular biology or tissue imaging; pathologists; neurologists; tumour biologists; ophthalmologists and cardiologists.
Автор: Ali Salajegheh Название: Angiogenesis in Health, Disease and Malignancy ISBN: 3319281380 ISBN-13(EAN): 9783319281384 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This book is about "Angiogenesis". A process in which new vasculature is formed from pre-existing capillaries. Angiogenesis process is associated with the proliferation and growth of both physiologically normal and neoplastic tissues, through the formation of vascular supply, essential for delivering growth requirements such as oxygen and nutrients.
The book describes more than 100 genes and their key regulatory functions in the context of normal healthy condition, disease and malignancy, cancer proliferation and progression. New insights into the role of angiogenesis and the therapeutic inhibition of its regulators are investigated, due to the great potential for exploitation in the development of a novel treatment for cancer.
New scientists, junior researchers and biomedical science students will find this book an invaluable introductory reference to their insight about angiogenesis and angiogenic role of more than 100 angiogenes and their role in healthy, disease and malignant conditions.
Описание: This book reviews and discusses knowledge gathered on Metabolic Syndrome and analyzes the interplay between oxidative stress, chronic inflammation and angiogenesis features. It focuses on recent discoveries and progress toward possible therapeutic strategies.
Автор: Dieter Marm?; Norbert Fusenig Название: Tumor Angiogenesis ISBN: 3662517981 ISBN-13(EAN): 9783662517987 Издательство: Springer Рейтинг: Цена: 50172.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
5. Therapeutic strategies, the concept of "normalization" and the role of VEGF inhibition
Index
Автор: Ribatti Название: Tumor Angiogenesis Assays ISBN: 1493939971 ISBN-13(EAN): 9781493939978 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume aims to provide a range of methods and protocols for studying tumor angiogenesis in vitro and in vivo to reflect advances in the field. The chapters in this book cover topics such as: morphological aspects of tumor angiogenesis, aortic ring assay and its use for the study of tumor angiogenesis, ex vivo tissue culture model for anti-angiogenic drug testing, transgenic zebrafish, orthotopic models of ovarian cancer, and uncovering metabolic effects of anti-angiogenic therapy in tumors by induced metabolic bioluminescence imaging. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting edge and thorough, Tumor Angiogenesis Assays: Methods and Protocols is a valuable resource for anyone interested in tumor angiogenesis assay research.
Автор: Shaker A. Mousa; Paul J. Davis Название: Angiogenesis Modulations in Health and Disease ISBN: 9400764669 ISBN-13(EAN): 9789400764668 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book offers in-depth explanations of pro-angiogenesis and anti-angiogenesis targets and their evaluation methods. Coverage includes preclinical and clinical methods and models, investigational status, and clinical applications.
Автор: Michael E. Maragoudakis Название: Molecular, Cellular, and Clinical Aspects of Angiogenesis ISBN: 1461380308 ISBN-13(EAN): 9781461380306 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of a NATO ASI held in Porto Carras, Halkidiki, Greece, June 16-27, 1995.
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