Автор: Figg Название: Angiogenesis ISBN: 0387715177 ISBN-13(EAN): 9780387715179 Издательство: Springer Рейтинг: Цена: 33428.00 р. Наличие на складе: Поставка под заказ.
Описание: Dr Judah Folkman (1933-2008) was considered the `father of angiogenesis`. Because of Folkman`s discovery and research, the possibilities of angiogenic therapy have broadened beyond cancer to many noncancerous diseases. This book presents a summary of tumor angiogenesis.
Автор: Michael E. Maragoudakis Название: Angiogenesis ISBN: 1475791879 ISBN-13(EAN): 9781475791877 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of a NATO ASI held in Rhodes, Greece, June 20-30, 1997
Автор: Shaker A. Mousa; Paul J. Davis Название: Angiogenesis Modulations in Health and Disease ISBN: 9401785155 ISBN-13(EAN): 9789401785150 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book offers in-depth explanations of pro-angiogenesis and anti-angiogenesis targets and their evaluation methods. Coverage includes preclinical and clinical methods and models, investigational status, and clinical applications.
Автор: Ribatti Название: History of Research on Tumor Angiogenesis ISBN: 9048181569 ISBN-13(EAN): 9789048181568 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In 1971, J. Folkman hypothesized that tumor growth is angiogenesis-dependent. In 2004, the FDA approved the first angiogenesis inhibitor. This book compiles the relevant literature of that history and emphasizes the antiangiogenic approach to treat tumors.
Автор: Dieter Marm? Название: Tumor Angiogenesis ISBN: 3319336711 ISBN-13(EAN): 9783319336718 Издательство: Springer Рейтинг: Цена: 76864.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This exhaustive work shows that new therapies using anti-angiogenic drugs are of particular importance because they can be used against many different types of cancer, as tumor angiogenesis seems to be involved in most if not all solid metastasizing malignancies. The first part of this book summarizes the knowledge acquired on the molecular entities that play a role in tumor angiogenesis and their mechanisms of action. Furthermore, the identification of molecular markers and their validation as predictive and/or prognostic tools is reviewed. In the second and most important part, the clinical applications of anti-angiogenic treatments are documented for a wide variety of tumors. In particular, the modes of combination with other targeted and/or cytotoxic cancer therapies are presented.
Автор: Ribatti Название: Tumor Angiogenesis Assays ISBN: 1493939971 ISBN-13(EAN): 9781493939978 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume aims to provide a range of methods and protocols for studying tumor angiogenesis in vitro and in vivo to reflect advances in the field. The chapters in this book cover topics such as: morphological aspects of tumor angiogenesis, aortic ring assay and its use for the study of tumor angiogenesis, ex vivo tissue culture model for anti-angiogenic drug testing, transgenic zebrafish, orthotopic models of ovarian cancer, and uncovering metabolic effects of anti-angiogenic therapy in tumors by induced metabolic bioluminescence imaging. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting edge and thorough, Tumor Angiogenesis Assays: Methods and Protocols is a valuable resource for anyone interested in tumor angiogenesis assay research.
5. Therapeutic strategies, the concept of "normalization" and the role of VEGF inhibition
Index
Автор: I.D. Goldberg; E.R. Rosen Название: Regulation of Angiogenesis ISBN: 3034898649 ISBN-13(EAN): 9783034898645 Издательство: Springer Рейтинг: Цена: 14673.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Michael E. Maragoudakis Название: Angiogenesis ISBN: 1461368952 ISBN-13(EAN): 9781461368953 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the 5th Biannual International Meeting on Angiogenesis: From the Molecular to Integrative Pharmacology, held July 1-7, 1999, in Crete, Greece.
Описание: Convertases are widely expressed activating enzymes involved in various physiological and pathological processes. The purpose of this book is to provide detailed and updated information on the role of these molecules in cancer. This book is the first to summarize current knowledge about the importance of protein precursors maturation by the convertases in tumor progression, angiogenesis and metastasis. In each chapter, the importance of the convertases in the activation of various cancer-related molecules including growth factors, adhesion molecules and proteases is discussed. Also this book covers the role of some convertases in the clinical setting. The book will be of interest to basic researchers as well as clinicians. It will also interest those working in the cancer research area and the pharmaceutical industry, who are looking for new strategies in cancer therapy. Finally, this book is also a useful reference for researchers and clinicians pursuing research on growth factors, adhesion molecules, proteases and their implications in the processes of tumor progression, angiogenesis and metastasis.
Автор: William D. Figg; Judah Folkman Название: Angiogenesis ISBN: 1489996680 ISBN-13(EAN): 9781489996688 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Dr. Judah Folkman, “father of angiogenesis”, (1933-2008) was the Director of the Vascular Biology Program, Andrus Professor of Pediatric Surgery, and Professor of Cell Biology at Harvard University's Boston Children's Hospital. In the 1971 issue of The New England Journal of Medicine, he proposed the theory that tumor growth is angiogenesis dependent. This premise was the basis of this field of research and has become the focus of scientists worldwide. Because of Folkman's discovery and research, the possibilities of antiangiogenic and angiogenic therapy have broadened beyond cancer to many noncancerous diseases. This book represents the first collection in a volume of which Dr. Folkman is co-editor. Dr. Folkman authored nearly 400 original papers and more than 100 book chapters. Dr. William Figg is the chief of the Molecular and Clinical Pharmacology Program at the National Cancer Institute, National Institutes of Health. Over the past 15 years, his laboratory and clinic at the NCI have focused on the development of angiogenesis inhibitors. Dr. Figg has published more than 380 publications.
Автор: Shaker A. Mousa; Paul J. Davis Название: Angiogenesis Modulations in Health and Disease ISBN: 9400764669 ISBN-13(EAN): 9789400764668 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book offers in-depth explanations of pro-angiogenesis and anti-angiogenesis targets and their evaluation methods. Coverage includes preclinical and clinical methods and models, investigational status, and clinical applications.
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