Stress-Induced Mutagenesis, David Mittelman

Автор: Mittelman David
Название: Stress-Induced Mutagenesis
ISBN: 1461462797 ISBN-13(EAN): 9781461462798
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Описание: This book covers pathways of stress-induced mutagenesis, which may yield models for genome instability underlying some cancers and genetic diseases, resistance to chemotherapeutic and antibiotic drugs, pathogenicity of microbes, and other important processes.

Автор: Robert Feil; Daniel Metzger
Название: Conditional Mutagenesis: An Approach to Disease Models
ISBN: 364207121X ISBN-13(EAN): 9783642071218
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Описание: With contributions by numerous experts

Автор: Adam J. Dupuy; David A. Largaespada
Название: Insertional Mutagenesis Strategies in Cancer Genetics
ISBN: 1489981349 ISBN-13(EAN): 9781489981349
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Описание: The goal of this work is summarize the contribution that insertional mutagenesis has made to our understanding of cancer. A variety of insertional mutagens are presented that have been used to study a variety of tumor types in several model organisms. In addition, the impact of insertional mutagenesis in several gene therapy trials is discussed along with strategies to avoid such complications in future clinical trials.

Автор: Y.F. Bogdanov; E. Dikomey; N.A. Liapunova; W.-U. M
Название: Advances in Mutagenesis Research
ISBN: 3642781950 ISBN-13(EAN): 9783642781957
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Описание: Applied genetic research, genetic toxicology and mutation research investigate the mutagenicity of chemicals and other agents. Permanent mutation in genes and chromosomes can be induced by a plethora of agents, including ionizing and nonionizing radiations, chemicals, and viruses.

Автор: A. Kappas
Название: Mechanisms of Environmental Mutagenesis-Carcinogenesis
ISBN: 1461366984 ISBN-13(EAN): 9781461366980
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Описание: Recent findings, techniques and methodologies in the area of biomonitoring of humans exposed to environmental mutagens-carcinogens were presented and considerable attention was also paid to the aspects and issues of collaborative environmental policy.

Автор: Frederick De Serres
Название: Comparative Chemical Mutagenesis
ISBN: 146133411X ISBN-13(EAN): 9781461334118
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Описание: ) 27709 The Workshop on Comparative Chemical Mutagenesis was orga- nized to begin the process of problem identification and resolution concerning our needs to evaluate the data on test chemicals arising from assays for mutagenic activity on laboratory organisms.

Автор: Shondra M. Pruett-Miller
Название: Chromosomal Mutagenesis
ISBN: 1493955411 ISBN-13(EAN): 9781493955411
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Описание: This new edition explores current and emerging mutagenesis methods focusing specifically on mammalian systems and commonly used model organisms through comprehensive coverage and detailed protocols.

Автор: F. Vogel; G. R?hrborn
Название: Chemical Mutagenesis in Mammals and Man
ISBN: 3642858767 ISBN-13(EAN): 9783642858765
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Описание: Encouraged by the results with radiation genetics, the editors of this volume have tried since 1963 to organize a team of scientists in Heidelberg who would examine the problem of chemical mutagenesis in mammals with a variety of methods. Meanwhile, other organizations have also become interested in this problem and various teams, particularly in the U.S.A., but also in West Germany, are working in this field. This development is very auspicious; the spectrum of our methods does permit limited conclusions as to the mutagenic effects of chemical substances in mammals, but we are still far away from a thorough determination of all the genetically relevant effects. New methods must be developed. This volume is the result of a request by the Chairman of the "Gesellschaft fUr Anthropologie und Humangenetik", Frau Professor Dr. I. SCHWIDETZKY (Mainz), that one of us (F.V.) organize a symposium concerning mutation research in the framework of its annual meeting on October 7, 1969. The most sensible approach seemed to be one of centering the discussion on the test methods employed in mutagenicity research with mammals. With the aid of the Deutsche Forschungsgemeinschaft and the pharma- ceutical industry it was possible to invite scientists from the U.S.A. We wish to thank Firma Thomae, Biberach, Firma Bayer, Leverkusen, and Firma Boehringer, Mannheim, for their contributions. We wish to thank Dr. HAsso SCHROEDER especially for his efforts on our behalf.

Автор: Burnet MacFarlane
Название: Intrinsic mutagenesis
ISBN: 9401166080 ISBN-13(EAN): 9789401166089
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Описание: The working hypothesis, which halfway through its writing became the new central theme of the book, arose when I was a member of a committee appointed by the Australian Academy of Science at the request of the Australian Government to advise on the danger from French nuclear tests in the South Pacific.

Автор: F.A. Beland; L.G. Cain; J.S. Felton; J.D. Groopman
Название: Chemical Carcinogenesis and Mutagenesis I
ISBN: 3642747779 ISBN-13(EAN): 9783642747779
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Описание: I have been privileged to witness and participate in the great growth of knowledge on chemical carcinogenesis and mutagenesis since 1939 when I entered graduate school in biochemistry at the University of Wisconsin- Madison.

Автор: Greg Davis; Kevin J. Kayser
Название: Chromosomal Mutagenesis
ISBN: 161737833X ISBN-13(EAN): 9781617378331
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Описание: In Chromosomal Mutagenesis, a team of experts provide a variety of chromosomal manipulation techniques, including insertional gene disruptions, gene knockouts, stimulated homologous recombination techniques and other novel tools, for both prokaryotic and eukaryotic organisms, and attempt to expand the genetic toolbox beyond model organisms.

Автор: W. Generoso
Название: DNA Repair and Mutagenesis in Eukaryotes
ISBN: 1468438441 ISBN-13(EAN): 9781468438444
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Описание: Not many years ago most discussion of mutation induction by physical and chemical agents concentrated on the initial lesions induced in the DNA with the implicit assumption that once the lesions were made they were converted almost automatically to mutations by relatively simple processes associated with DNA replication.