Small Molecule Therapeutics for Schizophrenia, Sylvain Celanire; Sonia Poli
Автор: Alexander E. Knight Название: Single Molecule Biology, ISBN: 0123742277 ISBN-13(EAN): 9780123742278 Издательство: Elsevier Science Рейтинг: Цена: 11789.00 р. Наличие на складе: Поставка под заказ.
Описание: Describes such single molecule techniques (that allow for manipulation and measurement of single biological molecules within a live cell) as single molecule fluorescence, optical tweezers, and scanning probe microscopy. This book is organized by biological system or molecule. It discusses applications in molecular diagnostics and drug discovery.
Автор: Mahesh Uttamchandani; Shao Q. Yao Название: Small Molecule Microarrays ISBN: 1493965824 ISBN-13(EAN): 9781493965823 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Small molecule microarrays (SMM) were introduced in 1999 and within just a short span of time, have established themselves as a vibrant next generation platform for high-throughput screening. Small Molecule Microarrays: Methods and Protocols consolidates a significant collection of examples, which serve to guide researchers toward ways in which SMM technology may be effectively deployed for multiplexed screening, drug discovery and ligand identification. The volume is organized into three sections covering microarray fabrication, imaging modes, and discovery approaches. The chapters cover a range of small molecule library types, ranging from synthetic combinatorial libraries to peptide and carbohydrate libraries, with lessons and techniques that can be widely applied. Written in the highly successful Methods in Molecular Biology series, format, chapters include introductions of their respective topics, lists of the requisite materials and reagents, step-by-step and readily reproducible laboratory protocols as well as vital tips on troubleshooting and advice on avoiding known pitfalls. Authoritative and cutting-edge, Small Molecule Microarrays: Methods and Protocols provides meticulous insights into the successful applications of SMM, by experts in the field. Building on this collection of knowledge, the volume seeks to inspire a future generation of microarray practitioners to propel this significant technology to even greater heights
Автор: Andrea C. Gore Название: GnRH: The Master Molecule of Reproduction ISBN: 1441949518 ISBN-13(EAN): 9781441949516 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book describes recent developments concerning structural, functional and possible therapeutic aspects of one particular CAM, the neural cell adhesion molecule (NCAM).
Автор: Sylvain Celanire; Sonia Poli Название: Small Molecule Therapeutics for Schizophrenia ISBN: 3319115014 ISBN-13(EAN): 9783319115016 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Antipsychotics and the Dopamine-Serotonin Connection.- GLYT1 Inhibitors: From Hits to Clinical Candidates.- Metabotropic Glutamate Receptor 2 Activators.- Activation of the mGlu5 Receptor for the Treatment of Schizophrenia and Cognitive-Deficit-Associated Disorders.- Muscarinic Acetylcholine Receptor Activators.- Nicotinic Acetylcholine Receptor Modulators.- The Use of PDE10A and PDE9 Inhibitors for Treating Schizophrenia.
Автор: Herbert Waldmann; Marcus Koppitz Название: Small Molecule — Protein Interactions ISBN: 3662053160 ISBN-13(EAN): 9783662053164 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Based on the international workshop on `Small Molecule - Protein Interactions` held in Berlin, April 24-26, 2002, researchers from industry and academic laboratories describe novel and efficient ways selecting promising new drug targets and developing small molecule inhibitors against them.
Автор: Mahesh Uttamchandani; Shao Q. Yao Название: Small Molecule Microarrays ISBN: 1493958151 ISBN-13(EAN): 9781493958153 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Small molecule microarrays (SMM) were introduced just a decade ago in 1999 and, within a short space of time, have already established themselves as a vibrant, next generation platform for high-throughput screening. Small Molecule Microarrays: Methods and Protocols showcases a collection of contributions guiding researchers toward ways in which small molecule microarray technology may be deployed for multiplexed screening and profiling. Organized by the categories of small molecules presented on the microarrays, this detailed volume describes in-depth techniques for chemical libraries, peptide libraries, and carbohydrate microarrays. Written in the highly successful Methods in Molecular Biology™ series, chapters contain brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, vital tips on troubleshooting this often difficult technology, and advice on avoiding known pitfalls. Authoritative and cutting-edge, Small Molecule Microarrays: Methods and Protocols provides meticulous depictions of key hands-on experience and seeks to inspire a future generation of microarray practitioners to take this significant technology forward.
Автор: Lane Название: Oxygen: The molecule that made the world ISBN: 0198607830 ISBN-13(EAN): 9780198607830 Издательство: Oxford Academ Рейтинг: Цена: 1582.00 р. Наличие на складе: Поставка под заказ.
Описание: Oxygen is the engine of life and evolution. This book explores the impact that oxygen has had on Earth, tracing the history of life from the very beginning. It explains the rise of animals and plants, the origin of two sexes, and the evolution of ageing and death.
Автор: Galizia, C. Giovanni; Lledo, Pierre-Marie (Eds.) Название: Neurosciences - From Molecule to Behavior: a university textbook ISBN: 3642107680 ISBN-13(EAN): 9783642107689 Издательство: Springer Рейтинг: Цена: 13080.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Neurosciences - a comprehensive approach This textbook covers neuroscience from cellular and molecular mechanisms to behavior and cognitive processing.
Автор: Gregory I. Mashanov; Christopher Batters Название: Single Molecule Enzymology ISBN: 149396190X ISBN-13(EAN): 9781493961900 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This an ideal guide for the diverse community of molecular biologists, biochemists, and biophysicists studying enzymes in detail. Experts in the field provide procedures which enable the extraction of detailed information about enzyme work cycles.
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