Amines and Their Metabolites, Alan A. Boulton; Glen B. Baker; Judith M. Baker
Автор: Abel Lajtha Название: Alterations of Metabolites in the Nervous System ISBN: 1475767420 ISBN-13(EAN): 9781475767421 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In neurosciences one may say, 'All roads lead to Rome. It seems as though wherever one starts, the course of investigation leads to the same major ques- tions about nervous system function and dysfunction. In thinking about what to write in this preface, it occurred to me that it might be best to deal with that with which I am most familiar and to trace to some extent my own 'road to Rome. '' As I look over my work of the last 37 years, it becomes clear to me that it can be epitomized as a search for patterns. What usually began as a single- minded devotion to in-depth analysis of one or a small number of variables always has led to questions of how the results might relate to the whole living unit, whether it is cell, tissue, or organism. For a number of years after my discovery in the vertebrate central nervous system of -y-aminobutyric acid (GABA) and the enzyme which forms it, L- glutamate decarboxylase (GAD), and the identification of GABA as a major inhibitory neurotransmitter by others, I felt that my laboratory, largely bio- chemical, was wandering in the wilderness of the complexities of the vertebrate CNS without definitively coming to terms with problems related to GABAergic transmitter functions and the roles of GABA neurons in information processing.
Описание: In response to the field's need for an introductory text, the authors have distilled the vast and scattered literature relating to the biotechnology of microbial secondary metabolites. General biology, biosynthesis, the search for novel metabolites, and techniques for strain improvement are all discussed to provide undergraduate and graduate students with a concise, readable overview of the field.
Автор: Alan A. Boulton; Peter R. Bieck; L. Maitre; P. Rie Название: Neuropsychopharmacology of the Trace Amines ISBN: 0896030997 ISBN-13(EAN): 9780896030992 Издательство: Springer Рейтинг: Цена: 30606.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A probable neurobiological role for the trace amines began to emerge as soon as techniques sufficiently sophisticated to detect them were developed.
Автор: Alan A. Boulton; Glen B. Baker; William G. Dewhurs Название: Neurobiology of the Trace Amines ISBN: 0896030636 ISBN-13(EAN): 9780896030633 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Many of the trace amines-more correctly called biogenic amines- have been known for decades, but because of their tiny concentra- tions (0. 01-100 ng/g) in brain, it was only after the development of sophisticated analytical techniques (such as mass spectrometry) that they could be identified and quantitated in nervous tissue. There are now more than 20 of them and most are related to the catecholamines and 5-hydroxytryptamine both structurally and metabolically. Their pharmacological and physiological properties make them prime candidates for a transmitter or neuromodulator role and many of them elicit profound behavioral syndromes after injection--one of them, phenylethylamine, has even been referred to as nature's amphetamine. In the clinical sphere several have been shown to be involved in: Parkinsonism, schizophrenia, depression, agoraphobia, aggression, hyperkinesis, migraine, hypertensive crises, hypertyrosinemia, he- patic encephalopathy, epilepsy, and cystic fibrosis. Thus the research reported here on these intriguing "new" substances will be of great interest to psychiatrists, neurologists, biochemists, pharmacologists, physiologists, psychologists, behaviorists and indeed to all those working in the neurosciences and related fields today. ACKNOWLEDGMENTS This book is based on the proceedings of Trace Amines and the Neurosciences, a meeting held at the University of Alberta, Edmonton, July 19-21, 1983. This meeting was organized as a Satellite Meeting of the Ninth Meeting of the International Society for Neurochemistry, held in Vancouver, July 10-15, 1983. International organizers of the satellite meeting were Drs. A. A. Boulton (Saskatoon), W. G. Dewhurst (Edmonton), G. B. Baker (Edmonton), and M. Sandler (London).
Автор: Alan A. Boulton; Glen B. Baker; William G. Dewhurs Название: Neurobiology of the Trace Amines ISBN: 1461297818 ISBN-13(EAN): 9781461297819 Издательство: Springer Рейтинг: Цена: 20896.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Alan A. Boulton; Glen B. Baker; Judith M. Baker Название: Amines and Their Metabolites ISBN: 1489941258 ISBN-13(EAN): 9781489941251 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Ajit Varma; Ram Prasad; Narendra Tuteja Название: Mycorrhiza - Eco-Physiology, Secondary Metabolites, Nanomaterials ISBN: 3319578480 ISBN-13(EAN): 9783319578484 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This is the fourth updated and revised edition of a well-received book that emphasises on fungal diversity, plant productivity and sustainability. It contains new chapters written by leading experts in the field.
This book is an up-to-date overview of current progress in mycorrhiza and association with plant productivity and environmental sustainability. The result is a must hands-on guide, ideally suited for agri-biotechnology, soil biology, fungal biology including mycorrhiza and stress management, academia and researchers.
The topic of this book is particularly relevant to researchers involved in mycorrhiza, especially to food security and environmental protection.
Mycorrhizas are symbioses between fungi and the roots of higher plants. As more than 90% of all known species of plants have the potential to form mycorrhizal associations, the productivity and species composition and the diversity of natural ecosystems are frequently dependent upon the presence and activity of mycorrhizas. The biotechnological application of mycorrhizas is expected to promote the production of food while maintaining ecologically and economically sustainable production systems.
Автор: Alan A. Boulton; A. V. Juorio; R. G. H. Downer Название: Trace Amines ISBN: 0896031446 ISBN-13(EAN): 9780896031449 Издательство: Springer Рейтинг: Цена: 34799.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume reflects the progress that has been made in the field of trace amines.
Автор: Farooqui, Tahira Название: Trace Amines and Neurological Disorders ISBN: 0128036036 ISBN-13(EAN): 9780128036037 Издательство: Elsevier Science Рейтинг: Цена: 17517.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Trace Amines and Neurological Disorders: Potential Mechanisms and Risk Factors explores trace amines which, under normal conditions, are present in the mammalian brain and peripheral nervous tissues at very low (nanomolar) concentrations. However, in a diverse array of human pathologies ranging from substance abuse, depression, attention deficit hyperactivity disorder, eating disorders, schizophrenia, and other neurological and neuropsychiatric diseases, the levels of trace amines are unusually high with an imbalance in their functions. Furthermore, the rapid turnover of trace amines is evidenced by their dramatic increases following treatment with monoamine oxidase inhibitors (MAOI) or deletion of the MAO genes. This suggests that the concentration of trace amines may be considerably higher at neuronal synapses than predicted by steady-state measures, implicating some pathophysiological role. Therefore, understanding molecular mechanisms and developing selective agonists and antagonists for trace amine-associated receptors (TAARs) has become a good approach for treating these diseases. Although the effects of trace amines at low physiological concentrations in mammalian species have been difficult to demonstrate, they may serve to maintain the neuronal activity of other monoamine neurotransmitters by possessing postsynaptic modulatory effects, particularly dopamine and serotonin, within defined physiological limits. Such an effect of trace amines makes them ideal candidates for the development of novel therapeutics for a wide range of human disorders. This book presents up-to-date, cutting-edge, and comprehensive information on the link between trace amines and neurological disorders.
Автор: Peter Riederer; Moussa B.H. Youdim Название: Amine Oxidases and Their Impact on Neurobiology ISBN: 3211822399 ISBN-13(EAN): 9783211822395 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Describes the most recent research in the field of monoamine oxidase (MAO), diamine oxidase and semicarbazide-sensitive amine oxidase. The roles of catechol-O-methyltransferase, sulfation and up-take processes are also discussed in detail.
Автор: Dinesh K. Maheshwari Название: Bacterial Metabolites in Sustainable Agroecosystem ISBN: 3319373315 ISBN-13(EAN): 9783319373317 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Plant growth promoting rhizobacteria are the soil bacteria inhabiting around/on the root surface and are directly or indirectly involved in promoting plant growth and development via production and secretion of various regulatory chemicals in the vicinity of rhizosphere.
Автор: Alan A. Boulton; Peter R. Bieck; L. Maitre; P. Rie Название: Neuropsychopharmacology of the Trace Amines ISBN: 1461293979 ISBN-13(EAN): 9781461293972 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A probable neurobiological role for the trace amines began to emerge as soon as techniques sufficiently sophisticated to detect them were developed.
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