Quantitative Aspects of Risk Assessment in Chemical Carcinogenesis, J. Clemmesen; A. Waring; D.M. Conning; D. Henschle

Автор: C.F. Arlett; Colin S. Cooper; Philip L. Grover; D.
Название: Chemical Carcinogenesis and Mutagenesis II
ISBN: 3642747809 ISBN-13(EAN): 9783642747809
Издательство: Springer
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Описание: I have been privileged to witness and participate in the great growth of knowledge on chemical carcinogenesis and mutagenesis since 1939 when I entered graduate school in biochemistry at the University of Wisconsin- Madison.

Автор: Max Costa
Название: Metal Carcinogenesis Testing
ISBN: 148994091X ISBN-13(EAN): 9781489940919
Издательство: Springer
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Цена: 13974.00 р.
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Описание: Metal Carcinogenesis Testing explains fundamental principles of metal carcinogenesis as they are currently understood, and provides detailed practical descriptions of rapid and inexpensive in vitro assay methodology presently in use for the detection of potentially carci- nogenic metals and their compounds.

Автор: Stavridis
Название: Oxidation: The Cornerstone of Carcinogenesis
ISBN: 9048177022 ISBN-13(EAN): 9789048177028
Издательство: Springer
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Цена: 20896.00 р.
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Описание: This book is unique due to its collective approach to the key aspects of the interdependency between three entities: oxidative stress, tobacco smoke and carcinogenesis, operating in a cause-effect sequence, in a concise and to the point manner.

Автор: F.A. Beland; L.G. Cain; J.S. Felton; J.D. Groopman
Название: Chemical Carcinogenesis and Mutagenesis I
ISBN: 3642747779 ISBN-13(EAN): 9783642747779
Издательство: Springer
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Цена: 16979.00 р.
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Описание: I have been privileged to witness and participate in the great growth of knowledge on chemical carcinogenesis and mutagenesis since 1939 when I entered graduate school in biochemistry at the University of Wisconsin- Madison.

Автор: George G. Chen; Paul B.S. Lai
Название: Novel Apoptotic Regulators in Carcinogenesis
ISBN: 9400794932 ISBN-13(EAN): 9789400794931
Издательство: Springer
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Цена: 25155.00 р.
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Описание: Our recent understanding of the cellular and molecular defects and the regulation of the apoptotic signalling pathways has resulted in rationally designed anticancer strategies and the development of novel agents that regulates apoptosis. A comprehensive review of all apoptotic-related anticancer therapies is not the purpose of this book. However, in the volume of this book with 11 chapters, we have described a number of novel apoptotic regulators that have shown promising value and also great feasibility for cancer treatment. These novel agents either occur naturally or are chemically synthesized. While we are excited about the discovery and development of these novel apoptotic regulators as potential anticancer agents, a degree of caution should be always borne in mind when interpreting the success of preclinical pro-apoptotic candidates since potential problems inevitably lie ahead. These problems usually include target specificity, unanticipated toxicity, compound stability, formulation issues, pharmacokinetic and pharmacodynamic profiles. Nevertheless, we believe that this collection of 11 chapters by established leaders in the area of apoptosis will be of great interest to not only academics working in the field of cancer research and apoptosis but also pharmaceutical and pharmacological industries that . We are looking forward to the further development to push these potential agents toward clinical stage.

Автор: Harri U. Vainio; Eino K. Hietanen
Название: Mechanisms in Carcinogenesis and Cancer Prevention
ISBN: 3642078591 ISBN-13(EAN): 9783642078590
Издательство: Springer
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Цена: 49631.00 р.
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Описание: This volume describes the present state of the art in carcinogenesis, possibilities for cancer prevention, and gives genetic background in cancer development. Attention is given to the host-environment interaction, considering how this interaction may lead to cancer formation and how it can be utilised in cancer prevention.

Автор: A. Cockburn; L. Smith
Название: Nongenotoxic Carcinogenesis
ISBN: 3662030241 ISBN-13(EAN): 9783662030240
Издательство: Springer
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Цена: 6986.00 р.
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Описание: The clarity of the view that all carcinogens act by mutating DNA, origin- ally advocated by Bruce Ames nearly 20 years ago, has been clouded by the increasing numbers of compounds which are not genotoxic but which nevertheless can cause cancer.

Автор: R.B. Barlow
Название: Quantitative Aspects of Chemical Pharmacology
ISBN: 0709903006 ISBN-13(EAN): 9780709903000
Издательство: Springer
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Цена: 12157.00 р.
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