Автор: Magnani Mauro Название: Erythrocyte Engineering for Drug Delivery and Targeting ISBN: 0306476916 ISBN-13(EAN): 9780306476914 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Includes topics such as electrochemical nuclear magnetic resonance (EC-NMR), the advances in the use of ab initio quantum chemical calculations in electrochemistry, the macroscopic and statistical thermodynamic models developed to describe adsorption phenomena on electrodes, and electrochemical promotion. This volume contains research results on plant lipids,including their structure, analysis, biosynthesis, regulation, physiological function, environmental aspects, and biotechnology, obtained world-wide during 2000-2002.
Автор: Gregory Gregoriadis; Brenda McCormack; George Post Название: Targeting of Drugs 4 ISBN: 1489912096 ISBN-13(EAN): 9781489912091 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of a NATO ASI held in Cape Sounion, Greece, June 24-July 5, 1993
Автор: Eric B. Kmiec Название: Gene Targeting Protocols ISBN: 1489941584 ISBN-13(EAN): 9781489941589 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The potential now exists in many experimental systems to transfer a cloned, modified gene back into the genome of the host organism. In the ideal situation, the cloned gene is returned to its homologous location in the genome and becomes inserted at the target locus. This process is a controlled means for the repair of DNA damage and ensures accurate chromosome disjunction during meiosis. The paradigm for thinking about the mechanism of this p- cess has emerged primarily from two sources: (1) The principles of reaction mechanics have come from detailed biochemical analyses of the RecA protein purified from Escherichia coli; and (2) the principles of information transfer have been derived from genetic studies carried out in bacteriophage and fungi. A compelling picture of the process of homologous pairing and DNA strand exchange has been influential in directing investigators interested in gene t- geting experiments. The ability to find and pair homologous DNA molecules enables ac- rate gene targeting and is the central phenomenon underlying genetic recombi- tion. Biochemically, the overall process can be thought of as a series of steps in a reaction pathway whereby DNA molecules are brought into homologous register, the four-stranded Holliday structure intermediate is formed, hete- duplex DNA is extended, and DNA strands are exchanged. Not much is known about the biochemical pathway leading to homologous recombination in euka- otes.
Автор: Dalbey/von Heijne Название: PROTEIN TARGETING, TRANSPORT & TRANSLOC ISBN: 012200731X ISBN-13(EAN): 9780122007316 Издательство: Elsevier Science Рейтинг: Цена: 12632.00 р. Наличие на складе: Поставка под заказ.
Описание: Presents an in-depth overview on the topic of protein synthesis and covers various areas of protein science, including protein targeting, secretion, folding, assembly, structure, localization, quality control, degradation, and antigen presentation. This book also includes sections on the history of the field and summary panels for quick reference.
Автор: Hurtley Название: Protein Targeting.1996 ISBN: 0199635617 ISBN-13(EAN): 9780199635610 Издательство: Oxford Academ Рейтинг: Цена: 13464.00 р. Наличие на складе: Поставка под заказ.
Описание: Protein targeting is the study of how proteins synthesized in one part of the cell reach their ultimate destination. This book is a preview of the latest research, which has applications for understanding cancer, studying diseases due to faulty targeting, and genetic manipulation of microorganisms.
Автор: Alistair J.P. Brown; Mick F. Tuite; John E.G. McCa Название: Protein Synthesis and Targeting in Yeast ISBN: 3642849237 ISBN-13(EAN): 9783642849237 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the NATO Advanced Research Workshop on Protein Synthesis and Targeting in Yeast, held at Canterbury, Kent, UK, July 4-8, 1992
Описание: Proteins act as macromolecular machinery that mediate many diverse biological processes - the molecular mechanisms of this machinery has fascinated biologists for decades. Analysis of the kinetic and thermodynamic features of these mechanisms could reveal unprecedented aspects of how the machinery function and will eventually lead to a novel understanding of various biological processes. This dissertation comprehensively demonstrates how two universally conserved guanosine triphosphatases in the signal recognition particle and its membrane receptor maintain the efficiency and fidelity of the co-translational protein targeting process essential to all cells. A series of quantitative experiments reveal that the highly ordered and coordinated conformational states of the machinery are the key to their regulatory function. This dissertation also offers a mechanistic view of another fascinating system in which multistate protein machinery closely control critical biological processes. Written while completing graduate work at California Institute of Technology.
Автор: Gregory Gregoriadis; Brenda McCormack Название: Targeting of Drugs 5 ISBN: 1461379431 ISBN-13(EAN): 9781461379430 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of a NATO ASI held in Cape Sounion, Greece, June 24-July 5, 1995
Автор: Phoenix D. A. Название: Protein Targeting and Translocation ISBN: 0691607397 ISBN-13(EAN): 9780691607399 Издательство: Wiley Рейтинг: Цена: 8237.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Protein targeting is a fast-moving field that has encompassed areas from biophysics to molecular biology to try to gain insight into how proteins are directed to their final functional location and how such macromolecules are able to cross semi-permeable membrane barriers during their journey. This text reviews our current state of knowledge regarding the interaction of proteins at the membrane interface and the assembly of proteins into biological membranes, before proceeding to look at targeting pathways in both prokaryotic and eukaryotic systems. The reviews have been written by some of the leading researchers in the field, with contributions from around the world and with more than 1,800 references. The text is aimed at graduate students and at researchers with an interest in protein targeting, but may also be of use to final-year undergraduates.
Originally published in 1999.
The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These paperback editions preserve the original texts of these important books while presenting them in durable paperback editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.
Автор: G. Gregoriadis Название: Receptor-Mediated Targeting of Drugs ISBN: 1468448641 ISBN-13(EAN): 9781468448641 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book, containing the proceedings of the 2nd NATO ASI "Receptor-Mediated Targeting of Drugs" held again at Cape Sounion, Greece during 20 June-l July 1983, deals with drug delivery through systems possessing ligands which can recognize and interact with receptors on the target`s surface.
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