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Tumorviruses, Neoplastic Transformation and Differentiation, T. Graf; R. Jaenisch


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Автор: T. Graf; R. Jaenisch
Название:  Tumorviruses, Neoplastic Transformation and Differentiation
ISBN: 9783642686566
Издательство: Springer
Классификация:



ISBN-10: 3642686567
Обложка/Формат: Paperback
Страницы: 200
Вес: 0.35 кг.
Дата издания: 10.12.2011
Серия: Current Topics in Microbiology and Immunology
Язык: English
Размер: 244 x 170 x 11
Основная тема: Biomedicine
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: If tumor viruses did not exist in nature they might have been created by scientists interested in basic mechanisms of develop- ment, differentiation, and tumorigenesis. In contemporary euka- ryotic cell biology tumor viruses playa similar role to that which bacteriophages once had for the molecular biology of prokary- otes. Tumor viruses provide extremely useful probes for the above cellular processes since their life cycle is genetically pro- grammed and can be followed at DNA, RNA, and protein levels. The experimental systems reviewed in this volume utilize a wide variety of viruses. A comprehensive introduction to this field has recently been published in the volumes of Molecular Biology o/Tumor Viruses: DNA Tumor Viruses, 2nd edition, edited by J. Tooze; and Molecular Biology o/Thmor Viruses: RNA Tumor Viruses, 2nd edition, edited by R. Weiss, N. Teich, H. Varmus, and J. Coffm, by Cold Spring Harbor Laboratories in 1980 and 1982. Polyoma and SV40 viruses (see the chapter by A. Levine) and adenoviruses (see the chapter by W. Doerfler) are double- stranded DNA-containing viruses. Polyoma and SV40 are struc- turally related viruses which contain a genome of approximately 5 kilo basepairs, while the DNA of adenovirus is about 7 times more complex. These DNA tumor viruses are understood at a genetic and molecular level which is comparable to our know- ledge of A and T4 bacteriophages. Retroviruses, the subject of the remaining four chapters, con- tain a single-stranded RNA genome of 5-8 kilobases.


Apoptosis: Biology and Mechanisms (Results and Problems in Cell Differentiation)

Автор: Sharad Kumar
Название: Apoptosis: Biology and Mechanisms (Results and Problems in Cell Differentiation)
ISBN: 366221623X ISBN-13(EAN): 9783662216231
Издательство: Springer
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Цена: 12157.00 р.
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Описание: Apoptosis is currently one of the fastest moving fields in biology with spectacular progress made over the past few years in delineating the molecular It is now indisputable that apoptosis mechanisms which underlie this process.

Tumor Cell Differentiation

Автор: Jarle Aarbakke; Peter K. Chiang; H. Phillip Koeffl
Название: Tumor Cell Differentiation
ISBN: 1461289416 ISBN-13(EAN): 9781461289418
Издательство: Springer
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Цена: 21661.00 р.
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Описание: This volume contains the proceedings of an International Sympo- sium on the Biology and Pharmacology of Tumor Cell Differentiation- held on June 29-July I, 1986 at the University of Tromso, Norway. The objective of this meeting was to bring together scientists from various disciplines to discuss recent advances in the understanding of tumor cell differentiation and to bridge the gap between experimental findings and clinical application of new knowledge. Thus the infor- mation will be of value not only to basic scientists involved in mol- ecular and cell biology, but also to pharmacologists and clinicians trying to develop the concept of tumor cell differentiation as a thera- peutic modality. Each plenary speaker and selected poster presenters were requested to submit a comprehensive, up-to-date review of recent contributions to their disciplines related to differentiation and: hematopoietic factors and leukemic cells in culture vitamin deriva- tives and polyamines; nucleosides and methylation; and cell interac- tions.

Adhesion in Leukocyte Homing and Differentiation

Автор: Dominique Dunon; Charles R. Mackay; Beat A. Imhof
Название: Adhesion in Leukocyte Homing and Differentiation
ISBN: 3642782558 ISBN-13(EAN): 9783642782558
Издательство: Springer
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Цена: 18167.00 р.
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Описание: Cell adhesion is one of the most dynamic fields of biological research and presented in this book is the current knowledge on the structure and function of the major families of cell adhesion molecules-the integrins, the selectins, the immunoglobulin superfamily, and CD44.

Growth Factors, Differentiation Factors, and Cytokines

Автор: Andreas Habenicht
Название: Growth Factors, Differentiation Factors, and Cytokines
ISBN: 3642748589 ISBN-13(EAN): 9783642748585
Издательство: Springer
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Цена: 15372.00 р.
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Описание: Leading international experts contribute to this selection of reviews covering the merging fields of growth factors, differentiation factors, and cytokines.

Transcriptional Control of Lineage Differentiation in Immune Cells

Автор: Wilfried Ellmeier; Ichiro Taniuchi
Название: Transcriptional Control of Lineage Differentiation in Immune Cells
ISBN: 331907394X ISBN-13(EAN): 9783319073941
Издательство: Springer
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Цена: 22203.00 р.
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Описание:

Genetic and epigenetic control of early lymphocyte development

Tomokatsu Ikawa

The role of BTB-zinc finger transcription factors during T cell development and in the regulation of T cell-mediated immunity

Wilfried Ellmeier and Ichiro Taniuchi

Transcriptional control of the development and function of Vα14i NKT cells

Isaac Engel and Mitchell Kronenberg

Transcriptional Control of Regulatory T cells

Michael Delacher, Lisa Schreiber, David D. Richards, Carla Farah, Markus Feuerer, Jochen Huehn

Transcriptional regulatory networks for CD4 T cell differentiation

Darah Christie and Jinfang Zhu

Transcriptional control of NK cell differentiation and function

Victoria Male and Hugh J.M. Brady

Transcriptional control of pre-B cell development and leukemia prevention

Swee Heng Milon Pang, Sebastian Carotta and Stephen L Nutt

Transcription factors controlling innate lymphoid cell fate decisions

Christoph S.N. Klose and Andreas Diefenbach

Transcriptional control of dendritic cell differentiation

Izumi Sasaki, Tsuneyasu Kaisho

Helper T cell plasticity: Impact of Extrinsic and Intrinsic Signals On Transcriptomes and Epigenomes

Michael Bonelli, Han-Yu Shih, Kiyoshi Hirahara, Kentner Singelton, Arian Laurence, Amanda Poholek, Tim Hand, Yohei Mikami, Golnaz Vahedi, Yuka Kanno and John J. O'Shea

Asymmetric Cell Division in Development, Differentiation and Cancer

Автор: Jean-Pierre Tassan; Jacek Z. Kubiak
Название: Asymmetric Cell Division in Development, Differentiation and Cancer
ISBN: 3319531492 ISBN-13(EAN): 9783319531496
Издательство: Springer
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Цена: 23757.00 р.
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Описание: Employing a broad range of examples, it highlights how this mode of cell division constitutes the basis of multicellular organism development and how its misregulation can lead to cancer.To underline such developmental correlations, readers will for example gain insights into stem cell fate and tumor growth.

Transcriptional Control of Lineage Differentiation in Immune Cells

Автор: Wilfried Ellmeier; Ichiro Taniuchi
Название: Transcriptional Control of Lineage Differentiation in Immune Cells
ISBN: 3319376519 ISBN-13(EAN): 9783319376516
Издательство: Springer
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Цена: 19589.00 р.
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Описание:

Genetic and epigenetic control of early lymphocyte development

Tomokatsu Ikawa

The role of BTB-zinc finger transcription factors during T cell development and in the regulation of T cell-mediated immunity

Wilfried Ellmeier and Ichiro Taniuchi

Transcriptional control of the development and function of Vα14i NKT cells

Isaac Engel and Mitchell Kronenberg

Transcriptional Control of Regulatory T cells

Michael Delacher, Lisa Schreiber, David D. Richards, Carla Farah, Markus Feuerer, Jochen Huehn

Transcriptional regulatory networks for CD4 T cell differentiation

Darah Christie and Jinfang Zhu

Transcriptional control of NK cell differentiation and function

Victoria Male and Hugh J.M. Brady

Transcriptional control of pre-B cell development and leukemia prevention

Swee Heng Milon Pang, Sebastian Carotta and Stephen L Nutt

Transcription factors controlling innate lymphoid cell fate decisions

Christoph S.N. Klose and Andreas Diefenbach

Transcriptional control of dendritic cell differentiation

Izumi Sasaki, Tsuneyasu Kaisho

Helper T cell plasticity: Impact of Extrinsic and Intrinsic Signals On Transcriptomes and Epigenomes

Michael Bonelli, Han-Yu Shih, Kiyoshi Hirahara, Kentner Singelton, Arian Laurence, Amanda Poholek, Tim Hand, Yohei Mikami, Golnaz Vahedi, Yuka Kanno and John J. O'Shea

T-Cell Differentiation

Автор: Lugli
Название: T-Cell Differentiation
ISBN: 1493965468 ISBN-13(EAN): 9781493965465
Издательство: Springer
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Цена: 19564.00 р.
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Описание: This volume provides protocols to successfully apply cutting-edge technologies to characterize the biology of T cells at an unprecedented level of complexity. Chapters guide readers through flow cytometry and fluorescence-activated cell sorting, the behaviour of single T cells after adoptive cell transfer (ACT), single cell gene expression by multiplex PCR, lentiviral transduction approaches, protocols to derive large numbers of early-differentiated memory T cells by using dedicated cytokines cocktails, approaches to measure telomerase activity in terminally differentiated T cells, and approaches to define Treg cells at the phenotypic and functional level. The final part of the book is dedicated to the analysis of the differentiation and effector functions of innate T cells, namely the well-known ?/? T cells, and the recently identified CD8+ mucosal associated invariant T (MAIT) cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, T-Cell Differentiation: Methods and Protocols aims to provide protocols that are fundamental to monitor the T cell compartment at the level of single cells in pathological and immunotherapy conditions.

T Helper Cell Differentiation and Their Function

Автор: Bing Sun
Название: T Helper Cell Differentiation and Their Function
ISBN: 9401794863 ISBN-13(EAN): 9789401794862
Издательство: Springer
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Цена: 20962.00 р.
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Описание: This book will focus on the differentiation and regulation of subsets of CD4+ T cells. It will also cover other aspects of research on these cells, which has made great advances in recent years, such as subsets’ plasticity and their role in healthy and disease conditions. The book provides researchers and graduate students with a cutting-edge and comprehensive overview of essential research on CD4+ T cells.

T Helper Cell Differentiation and Their Function

Автор: Bing Sun
Название: T Helper Cell Differentiation and Their Function
ISBN: 9402403191 ISBN-13(EAN): 9789402403190
Издательство: Springer
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Цена: 18284.00 р.
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Описание: This book will focus on the differentiation and regulation of subsets of CD4+ T cells. The book provides researchers and graduate students with a cutting-edge and comprehensive overview of essential research on CD4+ T cells.

Mammary Tumor Cell Cycle, Differentiation, and Metastasis

Автор: Robert B. Dickson; Marc E. Lippman
Название: Mammary Tumor Cell Cycle, Differentiation, and Metastasis
ISBN: 0792339053 ISBN-13(EAN): 9780792339052
Издательство: Springer
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Цена: 72533.00 р.
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Описание: This work is the fifth volume in a series designed to examine advances in the cellular and molecular biology of breast cancer. It looks at mouse models of mammary development and tumorigenesis, as well as studying human breast cancer, focusing on receptors, signalling, and the cell cycle.

Mammary Tumor Cell Cycle, Differentiation, and Metastasis

Автор: Robert B. Dickson; Marc E. Lippman
Название: Mammary Tumor Cell Cycle, Differentiation, and Metastasis
ISBN: 1461285364 ISBN-13(EAN): 9781461285366
Издательство: Springer
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Цена: 72533.00 р.
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Описание: Mammary Tumor Cell Cycle, Differentiation and Metastasis is the fifth volume since 1988 in a series designed to broadly examine current advances in the cellular and molecular biology of breast cancer.


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